Gene: Slc8a3

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Name
solute carrier family 8 (sodium/calcium exchanger), member 3
MGI ID
MGI:107976
Synonyms
Ncx3
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating sodium level Slc8a3tm1.1(KOMP)Vlcg HOM Early adult 2.16×10-08
increased hemoglobin content Slc8a3tm1.1(KOMP)Vlcg HOM Early adult 3.87×10-05
increased hematocrit Slc8a3tm1.1(KOMP)Vlcg HOM Early adult 6.71×10-06
shortened ST segment Slc8a3tm1.1(KOMP)Vlcg HOM Early adult 2.14×10-05
increased erythrocyte cell number Slc8a3tm1.1(KOMP)Vlcg HOM Early adult 2.34×10-06
shortened QT interval Slc8a3tm1.1(KOMP)Vlcg HOM Early adult 6.60×10-06
increased circulating alkaline phosphatase level Slc8a3tm1.1(KOMP)Vlcg HOM Early adult 3.50×10-05
increased startle reflex Slc8a3tm1.1(KOMP)Vlcg HOM Early adult 4.08×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Brain 2 No  (3/590)  (2/2)  Section images
Brainstem 2 No  (2/590)  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (3/590)  (2/2)  Section images
Cerebral cortex 2 No  (2/590)  (2/2)  Section images
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590)  (2/2)  Section images
Hypothalamus 2 No  (2/590)  (2/2)  Section images
Kidney 2 No  (20/590)  (2/2)  Section images
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/590)  (2/2)  Section images
Ovary 2 No  (1/590)  (1/2)  Section images
Oviduct 2 No  Section images
Pancreas 2 No  (5/590) N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590)  (2/2)  Section images
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590) N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (5/590)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590)  (1/2)  Section images
Trachea 2 No  (2/590)  (2/2)  Section images
Urinary bladder 2 No N/A
Uterus 2 No  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/506) N/A
Ear 1  (1/506) N/A
Embryo 1  (1/507)  (1/2)  Wholemount images
Eye 1  (1/506) N/A
Foot 1  (1/506) N/A
Forebrain 1  (1/506) N/A
Forelimb 1  (1/506)  (1/2) N/A
Hand 1  (1/506) N/A
Head 1  (5/506)  (1/2) N/A
Heart 1  (1/506) N/A
Hindbrain 1  (6/506) N/A
Hindlimb 1  (1/506)  (1/2) N/A
Liver 1  (1/504) N/A
Lung 1  (1/504) N/A
Mandibular process 1  (1/506)  (1/2) N/A
Maxillary process 1  (1/506)  (1/2) N/A
Midbrain 1  (1/506) N/A
Nose 1  (1/76)  (1/1) N/A
Oral cavity 1  (1/504) N/A
Rib pre-cartilage condensation 1  (1/58)  (1/1) N/A
Skin 1  (1/506) N/A
Tail 1  (1/506) N/A
Tail somite 1  (1/506) N/A

 Associated Images

X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Original Image
Adult LacZ: LacZ Images Section
20 Images
Combined SHIRPA and Dysmorphology
5 Images
Eye Morphology: Images Ophthalmoscopy
6 Images
Sleep Wake: Wake state (bmp file)
16 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Embryo LacZ: LacZ images wholemount
8 Images
Eye Morphology: Images Slit Lamp
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Slc8a3tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Slc8a3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Slc8a3tm464123(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo) Targeting vectors

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