Ifng | interferon gamma

GeneMGI:107656Synonyms: Ifg, IFN-gamma

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Nervous system Respiratory system Hematopoietic system Mortality/aging

16 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
8Associated diseases
Expression examined in:73Adult tissues
29Embryo tissues

Phenotypes

abnormal lung morphology1 supporting datasetIfngtm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
decreased prepulse inhibition2 supporting datasetsIfngtm1.1(KOMP)VlcgheterozygoteEarly adult4.59x10-9 
increased hematocrit1 supporting datasetIfngtm1.1(KOMP)VlcgheterozygoteEarly adult4.83x10-5 
embryonic lethality prior to organogenesis1 supporting datasetIfngtm1.1(KOMP)VlcghomozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsIfngtm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetIfngtm1.1(KOMP)VlcghomozygoteE12.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ifngtm1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell
Ifngtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Ifngtm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Ifngtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ifngtm2(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell

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