Ppp3ca | protein phosphatase 3, catalytic subunit, alpha isoform
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Growth/size/body region Hematopoietic system Behavior/neurological
13 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
5Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
increased body weight | 2 supporting datasets | Ppp3catm2e(EUCOMM)Wtsi | homozygote | Early adult | 2.12x10-6 | ||
increased blood urea nitrogen level | 1 supporting dataset | Ppp3catm2e(EUCOMM)Wtsi | homozygote | Early adult | 1.67x10-6 | ||
abnormal tail movements | 1 supporting dataset | Ppp3catm2e(EUCOMM)Wtsi | homozygote | Early adult | 5.6x10-6 | ||
decreased circulating magnesium level | 1 supporting dataset | Ppp3catm2e(EUCOMM)Wtsi | homozygote | Early adult | 3.4x10-5 | ||
decreased mean corpuscular volume | 1 supporting dataset | Ppp3catm2e(EUCOMM)Wtsi | homozygote | Early adult | 3.84x10-5 | ||
abnormal coat/hair pigmentation | 1 supporting dataset | Ppp3catm2e(EUCOMM)Wtsi | homozygote | Early adult | 2.34x10-6 | ||
decreased circulating amylase level | 1 supporting dataset | Ppp3catm2e(EUCOMM)Wtsi | homozygote | Early adult | 6.22x10-5 |
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External links
No external links available for Ppp3ca.
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Ppp3catm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Ppp3catm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
Ppp3catm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Ppp3catm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell mouse |
Ppp3catm3e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
Ppp3catm42411(L1L2_Pgk_PM) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
Ppp3catm42411(L1L2_st1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |