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Genes Phenotypes Help, News, Blog

Gene: Ppp3ca

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Name
protein phosphatase 3, catalytic subunit, alpha isoform
MGI ID
MGI:107164
Synonyms
PP2B alpha 1 PP2BA alpha CnA Caln Calna 2900074D19Rik CN
Viability
No data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (134) All data table (242)
Expression & images (45) Disease models (0) Order (5)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal coat/hair pigmentation Ppp3catm2e(EUCOMM)Wtsi HOM   Early adult 2.36×10-06
decreased circulating amylase level Ppp3catm2e(EUCOMM)Wtsi HOM Early adult 4.64×10-07
abnormal tail movements Ppp3catm2e(EUCOMM)Wtsi HOM   Early adult 5.59×10-06
decreased circulating magnesium level Ppp3catm2e(EUCOMM)Wtsi HOM Early adult 5.61×10-05

Download data as:  TSV  XLS

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (4/583) N/A
Aorta 1 No  (1/583) N/A
Blood vessel 1 No N/A
Bone 1 No N/A
Brain 1 No  (4/583) N/A
Brainstem 1 No  (2/583) N/A
Brown adipose tissue 1 No N/A
Cartilage tissue 1 No  (1/583) N/A
Cerebellum 1 No  (3/583) N/A
Cerebral cortex 1 No  (2/583) N/A
Eye 1 No N/A
Gall bladder 1 No N/A
Heart 1 No  (2/583) N/A
Hippocampus 1 No  (3/583) N/A
Hypothalamus 1 No  (2/583) N/A
Kidney 1 No  (21/583) N/A
Large intestine 1 No  (10/583) N/A
Liver 1 No N/A
Lower urinary tract 1 No  (1/583) N/A
Lung 1 No  (2/583) N/A
Lymph node 1 No  (1/583) N/A
Mammary gland 1 No N/A
Esophagus 1 No N/A
Olfactory lobe 1 No  (2/583) N/A
Ovary 1 No  (1/583) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/583) N/A
Parathyroid gland 1 No  (1/563) N/A
Peripheral nervous system 1 No  (2/583) N/A
Peyer's patch 1 No  (1/176) N/A
Pituitary gland 1 No  (1/583) N/A
Prostate gland 1 No  (12/583) N/A
Skeletal muscle tissue 1 No N/A
Skin 1 No  (1/583) N/A
Small intestine 1 No  (9/583) N/A
Spinal cord 1 No  (3/583) N/A
Spleen 1 No  (3/583) N/A
Stomach 1 No  (13/583) N/A
Striatum 1 No  (3/583) N/A
Testis 1 No  (6/583) N/A
Thymus 1 No  (1/583) N/A
Thyroid gland 1 No  (17/583) N/A
Trachea 1 No  (3/583) N/A
Uterus 1 No N/A
White adipose tissue 1 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Ppp3catm2e(EUCOMM)Wtsi
testis, HET, Male, WTSI
Ppp3catm2e(EUCOMM)Wtsi
testis, HET, Male, WTSI
Ppp3catm2e(EUCOMM)Wtsi
testis, HET, Male, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Ppp3catm2e(EUCOMM)Wtsi
body, HOM, Male, WTSI
Ppp3catm2e(EUCOMM)Wtsi
body, HOM, Male, WTSI
Ppp3catm2e(EUCOMM)Wtsi
head, HOM, Male, WTSI
Ppp3catm2e(EUCOMM)Wtsi
head, HOM, Male, WTSI
Ppp3catm2e(EUCOMM)Wtsi
body, HOM, Female, WTSI

View all 65 images

Ppp3catm2e(EUCOMM)Wtsi
abnormal epidermis stratum basale morphology, HOM, Female, WTSI
Ppp3catm2e(EUCOMM)Wtsi
abnormal epidermis stratum basale morphology, HOM, Female, WTSI
Ppp3catm2e(EUCOMM)Wtsi
abnormal epidermis stratum basale morphology, HOM, Female, WTSI
Ppp3catm2e(EUCOMM)Wtsi
abnormal epidermis stratum basale morphology, HOM, Female, WTSI
Ppp3catm2e(EUCOMM)Wtsi
back skin, HOM, Female, WTSI
Ppp3catm2e(EUCOMM)Wtsi
back skin, HOM, Female, WTSI
Ppp3catm2e(EUCOMM)Wtsi
eye, abnormal retinal pigmentation, HOM, Male, WTSI

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ppp3catm42411(L1L2_Pgk_PM) Targeting vectors
Ppp3catm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Ppp3catm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Ppp3catm2e(EUCOMM)Wtsi Targeted, non-conditional allele Mice
Ppp3catm42411(L1L2_st1) Targeting vectors

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