Genes Phenotypes Help, News, Blog

Please enable javascript if you want to log in to follow or stop following this gene.

Gene: Cox7c MGI:103226

Gene Summary

Name:

cytochrome c oxidase subunit 7C

Synonyms:

Cox7c1, COXVIIc

Order Alleles

IMPC Data Collections

IMPC Phenotype Summary

Significant

Not Significant

Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype	Allele	Zyg	Life Stage	P Value
abnormal placenta size	Cox7c^{tm1b(KOMP)Mbp}	HOM	E15.5	0.00
embryonic growth retardation	Cox7c^{tm1b(KOMP)Mbp}	HOM	E12.5	0.00
abnormal embryo size	Cox7c^{tm1b(KOMP)Mbp}	HOM	E12.5	0.00
abnormal placenta development	Cox7c^{tm1b(KOMP)Mbp}	HOM	E12.5	0.00
abnormal limb bud morphology	Cox7c^{tm1b(KOMP)Mbp}	HOM	E12.5	0.00
abnormal embryo size	Cox7c^{tm1b(KOMP)Mbp}	HOM	E15.5	0.00
pallor	Cox7c^{tm1b(KOMP)Mbp}	HOM	E12.5	0.00
increased fasting circulating glucose level	Cox7c^{tm1b(KOMP)Mbp}	HET	Early adult	1.04×10^-05
preweaning lethality, complete penetrance	Cox7c^{tm1b(KOMP)Mbp}	HOM	Early adult	0.00
prenatal lethality	Cox7c^{tm1b(KOMP)Mbp}	HOM	E18.5	0.00
abnormal skin coloration	Cox7c^{tm1b(KOMP)Mbp}	HOM	E15.5	0.00
abnormal placenta size	Cox7c^{tm1b(KOMP)Mbp}	HOM	E12.5	0.00
abnormal placenta morphology	Cox7c^{tm1b(KOMP)Mbp}	HOM	E12.5	0.00

Download data as: TSV XLS

Select physiological systems to view:

Viewing: all phenotypes

Select physiological systems to view:

Viewing: all phenotypes

lacZ Expression

An assay measuring the expression of lacZ shows the tissue where the gene is expressed.

Anatomy	Images	Zygosity	Mutant Expr
Adrenal gland	Section images	heterozygote	100% (2 of 2)
Aorta	Section images	heterozygote	100% (2 of 2)
Brain	Section images	heterozygote	100% (2 of 2)
Brainstem	Section images	heterozygote	100% (2 of 2)
Cartilage tissue	Section images	heterozygote	100% (2 of 2)
Cerebellum	Section images	heterozygote	100% (2 of 2)
Cerebral cortex	Section images	heterozygote	100% (2 of 2)
Epididymis	Section images	heterozygote	50% (1 of 2)
Esophagus	Section images	heterozygote	100% (2 of 2)
Eye	Section images	heterozygote	100% (2 of 2)
Heart	Section images	heterozygote	100% (2 of 2)
Hippocampus	Section images	heterozygote	100% (2 of 2)
Hypothalamus	Section images	heterozygote	100% (2 of 2)
Kidney	Section images	heterozygote	100% (2 of 2)
Large intestine	Section images	heterozygote	100% (2 of 2)
Liver	Section images	heterozygote	100% (2 of 2)
Lung	Section images	heterozygote	100% (2 of 2)
Midbrain	Section images	heterozygote	100% (2 of 2)
Olfactory lobe	Section images	heterozygote	100% (2 of 2)
Ovary	Section images	heterozygote	50% (1 of 2)
Oviduct	Section images	heterozygote	50% (1 of 2)
Pancreas	Section images	heterozygote	100% (2 of 2)
Peripheral nervous system	Section images	heterozygote	100% (2 of 2)
Pituitary gland	Section images	heterozygote	50% (1 of 2)
Skin	Section images	heterozygote	100% (2 of 2)
Small intestine	Section images	heterozygote	100% (2 of 2)
Spinal cord	Section images	heterozygote	100% (2 of 2)
Stomach	Section images	heterozygote	100% (2 of 2)
Submandibular gland	Section images	heterozygote	100% (2 of 2)
Testis	Section images	heterozygote	50% (1 of 2)
Thalamus	Section images	heterozygote	100% (2 of 2)
Thymus	Section images	heterozygote	100% (2 of 2)
Thyroid gland	Section images	heterozygote	50% (1 of 2)
Trachea	Section images	heterozygote	100% (2 of 2)
Urinary bladder	Section images	heterozygote	100% (2 of 2)
Uterus	Section images	heterozygote	50% (1 of 2)
Brown adipose tissue	N/A	heterozygote	0.0% (0 of 2)
Lower urinary tract	N/A	heterozygote	Not available
Lymph node	N/A	heterozygote	0.0% (0 of 2)
Mammary gland	N/A	heterozygote	0.0% (0 of 2)
Peyer's patch	N/A	heterozygote	Not available
Prostate gland	N/A	heterozygote	Not available
Skeletal muscle	N/A	heterozygote	0.0% (0 of 2)
Spleen	N/A	heterozygote	0.0% (0 of 2)
Striatum	N/A	heterozygote	Not available
Vascular system	N/A	heterozygote	100% (2 of 2)
Vesicular gland	N/A	heterozygote	Not available
White adipose tissue	N/A	heterozygote	0.0% (0 of 2)

An assay measuring the expression of lacZ shows the tissue where the gene is expressed.

Anatomy	Images	Zygosity	Mutant Expr
Embryo	N/A	heterozygote	100% (2 of 2)
Embryo	N/A	homozygote	Ambiguous
Brain	N/A	heterozygote	100% (2 of 2)
Brain	N/A	homozygote	Ambiguous
Dorsal root ganglion	N/A	heterozygote	Ambiguous
	N/A		Ambiguous
Ear	N/A	heterozygote	Ambiguous
Ear	N/A	homozygote	Ambiguous
Eye	N/A	heterozygote	100% (2 of 2)
Eye	N/A	homozygote	Ambiguous
Footplate	N/A	heterozygote	50% (1 of 2)
Footplate	N/A	homozygote	Ambiguous
Forebrain	N/A	heterozygote	100% (2 of 2)
Forebrain	N/A	homozygote	Ambiguous
Forelimb	N/A	heterozygote	100% (2 of 2)
Forelimb	N/A	homozygote	Ambiguous
Fronto-nasal process	N/A	heterozygote	Ambiguous
	N/A		Ambiguous
Handplate	N/A	heterozygote	50% (1 of 2)
Handplate	N/A	homozygote	Ambiguous
Head	N/A	heterozygote	100% (2 of 2)
Head	N/A	homozygote	Ambiguous
Heart	N/A	heterozygote	100% (2 of 2)
Heart	N/A	homozygote	Ambiguous
Hindbrain	N/A	heterozygote	100% (2 of 2)
Hindbrain	N/A	homozygote	Ambiguous
Hindlimb	N/A	heterozygote	100% (2 of 2)
Hindlimb	N/A	homozygote	Ambiguous
Liver	N/A	heterozygote	0.0% (0 of 2)
Liver	N/A	homozygote	Ambiguous
Lung	N/A	heterozygote	Ambiguous
Lung	N/A	homozygote	Ambiguous
Mandibular process	N/A	heterozygote	100% (2 of 2)
Mandibular process	N/A	homozygote	Ambiguous
Maxillary process	N/A	heterozygote	100% (2 of 2)
Maxillary process	N/A	homozygote	Ambiguous
Midbrain	N/A	heterozygote	100% (2 of 2)
Midbrain	N/A	homozygote	Ambiguous
Nose	N/A	heterozygote	100% (1 of 1)
	N/A		Ambiguous
Oral cavity	N/A	heterozygote	50% (1 of 2)
Oral cavity	N/A	homozygote	Ambiguous
Skin	N/A	heterozygote	100% (2 of 2)
Skin	N/A	homozygote	Ambiguous
Spinal cord	N/A	heterozygote	100% (1 of 1)
	N/A		Ambiguous
Tail somite	N/A	heterozygote	50% (1 of 2)
Tail somite	N/A	homozygote	Ambiguous
Tail	N/A	heterozygote	50% (1 of 2)
Tail	N/A	homozygote	Ambiguous

Background staining occurs in wild type mice and embryos at an incidental rate.

Anatomy	Background staining in controls (WT)
adrenal gland	0.67% (4 of 598)
aorta	0.17% (1 of 598)
brain	0.84% (5 of 598)
brainstem	0.33% (2 of 598)
brown adipose tissue	0.0%
cartilage tissue	0.17% (1 of 598)
cerebellum	0.5% (3 of 598)
cerebral cortex	0.33% (2 of 598)
epididymis	14.29% (21 of 147)
esophagus	1.66% (7 of 422)
eye	0.0%
heart	0.33% (2 of 598)
hippocampus	0.5% (3 of 598)
hypothalamus	0.33% (2 of 598)
kidney	4.52% (27 of 598)
large intestine	5.35% (32 of 598)
liver	0.0%
lower urinary tract	0.17% (1 of 598)
lung	0.33% (2 of 598)
lymph node	0.17% (1 of 598)
mammary gland	0.0%
midbrain	0.0%
olfactory lobe	0.33% (2 of 598)
ovary	0.17% (1 of 598)
oviduct	0.0%
pancreas	0.84% (5 of 598)
peripheral nervous system	0.33% (2 of 598)
peyers patch	0.0%
pituitary gland	0.17% (1 of 598)
prostate gland	2.17% (13 of 598)
skeletal muscle	0.0%
skin	0.17% (1 of 598)
small intestine	5.35% (32 of 598)
spinal cord	0.5% (3 of 598)
spleen	0.5% (3 of 598)
stomach	3.68% (22 of 598)
striatum	0.5% (3 of 598)
submandibular gland	1.38% (2 of 145)
testis	1% (6 of 598)
thalamus	0.0%
thymus	0.17% (1 of 598)
thyroid gland	3.01% (18 of 598)
trachea	0.5% (3 of 598)
urinary bladder	0.0%
uterus	0.33% (2 of 598)
vascular system	0.0%
vesicular gland	0.0%
white adipose tissue	0.0%

Background staining occurs in wild type mice and embryos at an incidental rate.

Background staining occurs in wild type embryos at a measurable rate.

Anatomy	Background staining in controls(WT)
brain	1.17% (6 of 511)
dorsal root ganglion	1.67% (1 of 60)
ear	0.2% (1 of 511)
embryo	0.39% (2 of 512)
eye	0.2% (1 of 511)
footplate	0.2% (1 of 511)
forebrain	0.2% (1 of 511)
forelimb	0.2% (1 of 511)
fronto-nasal process	1.64% (1 of 61)
handplate	0.2% (1 of 511)
head	0.98% (5 of 511)
heart	0.2% (1 of 511)
hindbrain	1.17% (6 of 511)
hindlimb	0.2% (1 of 511)
liver	0.2% (1 of 506)
lung	0.2% (1 of 506)
mandibular process	0.2% (1 of 511)
maxillary process	0.2% (1 of 511)
midbrain	0.2% (1 of 511)
nose	1.28% (1 of 78)
oral cavity	0.2% (1 of 506)
skin	0.2% (1 of 511)
spinal cord	1.39% (1 of 72)
tail	0.2% (1 of 511)
tail somite group	0.2% (1 of 511)

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Adult LacZ

LacZ Images Section

37 Images

View images

X-ray

XRay Images Skull Lateral Orientation

10 Images

View images

Sleep Wake

Wake state (bmp file)

13 Images

View images

Gross Morphology Embryo E12.5

6 Images

View images

Gross Morphology Embryo E18.5

Images

2 Images

View images

Electroretinography

Rod waveform (pdf format)

4 Images

View images

Auditory Brain Stem Response

Click-evoked + 6 to 30kHz tone waveforms (pdf format)

7 Images

View images

Electroretinography

Cone waveform (pdf format)

4 Images

View images

Human diseases caused by Cox7c mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

Human diseases associated with Cox7c (0 diseases)
Human diseases predicted to be associated with Cox7c (143 diseases)

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Cox7c by phenotypic similarity.

Disease	Matching phenotypes	Source
Maturity-Onset Diabetes Of The Young, Type 3	Hyperglycemia, Type II diabetes mellitus, Maturity-onset diabetes of the young	OMIM:600496
Hyperproinsulinemia	Hyperglycemia, Hyperinsulinemia	OMIM:616214
Maturity-Onset Diabetes Of The Young, Type 10	Diabetes mellitus, Hyperglycemia, Diabetic ketoacidosis, Maturity-onset diabetes of the young	OMIM:613370
Glycogen Storage Disease 0, Liver	Fasting hypoglycemia, Neonatal hypoglycemia, Postprandial hyperglycemia	OMIM:240600
Osteoporosis-Oculocutaneous Hypopigmentation Syndrome	Short stature, Hypopigmentation of the skin, Albinism, Pallor	ORPHA:2786
Diabetes Mellitus, Transient Neonatal, 1	Hyperglycemia, Transient neonatal diabetes mellitus	OMIM:601410
Hypogonadism, Male, With Mental Retardation And Skeletal Anomalies	Hyperglycemia, Glucose intolerance	OMIM:307500
Hereditary Persistence Of Fetal Hemoglobin-Beta-Thalassemia Syndrome	Pallor	ORPHA:46532
Methylmalonic Acidemia With Homocystinuria, Type Cbld	Pallor	ORPHA:79283
Peripheral Cone Dystrophy	Pallor	OMIM:609021
Cone-Rod Dystrophy 11	Pallor	OMIM:610381
Diabetes Mellitus, Permanent Neonatal, 4	Hyperglycemia, Type I diabetes mellitus, Diabetic ketoacidosis	OMIM:618858
X-Linked Sideroblastic Anemia	Hyperpigmentation of the skin, Pallor	ORPHA:75563
Diabetes Mellitus, Transient Neonatal, 3	Hyperglycemia, Maternal diabetes, Transient neonatal diabetes mellitus	OMIM:610582
Essential Fructosuria	Hyperglycemia	ORPHA:2056
Maturity-Onset Diabetes Of The Young, Type 13	Diabetes mellitus, Maternal diabetes, Hyperglycemia, Maturity-onset diabetes of the young	OMIM:616329
Acute Peripheral Arterial Occlusion	Pallor	ORPHA:90064
Optic Atrophy 1	Pallor	OMIM:165500
Dermatitis, Atopic	Dry skin, Facial erythema, Pallor	OMIM:603165
Benign Paroxysmal Torticollis Of Infancy	Pallor	ORPHA:71518
Autoimmune Hemolytic Anemia, Cold Type	Pallor	ORPHA:228312
Breath-Holding Spells	Pallor	OMIM:607578
Diabetes Mellitus, Permanent Neonatal, 1	Diabetes mellitus, Hyperglycemia, Type I diabetes mellitus	OMIM:606176
Leber Congenital Amaurosis 14	Pallor	OMIM:613341
Maturity-Onset Diabetes Of The Young, Type 8, With Exocrine Dysfunction	Hyperglycemia, Maturity-onset diabetes of the young	OMIM:609812
Myopathy, Lactic Acidosis, And Sideroblastic Anemia 2	Pallor, Growth delay	OMIM:613561
Transient Neonatal Diabetes Mellitus	Maternal diabetes, Hyperglycemia, Transient neonatal diabetes mellitus, Hypoinsulinemia, Maturity...	ORPHA:99886
Optic Atrophy 7 With Or Without Auditory Neuropathy	Pallor	OMIM:612989
Acute Myelomonocytic Leukemia	Pallor	ORPHA:517
Hemoglobin D Disease	Pallor	ORPHA:90039
Primary Lateral Sclerosis, Juvenile	Pallor	OMIM:606353
Familial Focal Epilepsy With Variable Foci	Pallor	ORPHA:98820
Anemia, Congenital Dyserythropoietic, Type Ib	Short stature, Pallor, Growth delay	OMIM:615631
Cyclic Vomiting Syndrome	Pallor, Growth delay	OMIM:500007
Thiamine-Responsive Megaloblastic Anemia Syndrome	Short stature, Pallor	ORPHA:49827
Type 1 Diabetes Mellitus	Diabetes mellitus, Hyperglycemia	OMIM:222100
Cone-Rod Synaptic Disorder Syndrome, Congenital Nonprogressive	Hyperglycemia	OMIM:618970
Anemia, Hypochromic Microcytic, With Iron Overload 2	Cafe-au-lait spot, Pallor, Growth delay	OMIM:615234
Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities	Fasting hypoglycemia, Postprandial hyperglycemia, Hyperinsulinemia, Hyperglycemia, Diabetic ketoa...	OMIM:262190
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome	Pallor	ORPHA:276608
Spontaneous Periodic Hypothermia	Pallor	ORPHA:29822
Severe Early-Onset Obesity-Insulin Resistance Syndrome Due To Sh2B1 Deficiency	Hyperglycemia, Hyperinsulinemia	ORPHA:329249
Fanconi Anemia, Complementation Group I	Short stature, Cafe-au-lait spot, Intrauterine growth retardation, Pallor	OMIM:609053
Retinitis Pigmentosa 51	Pallor	OMIM:613464
Hyperinsulinism Due To Ucp2 Deficiency	Pallor	ORPHA:276556
Diabetes Mellitus, Permanent Neonatal, 3	Hyperglycemia, Type I diabetes mellitus, Glycosuria	OMIM:618857
Autosomal Dominant Hyperinsulinism Due To Sur1 Deficiency	Pallor	ORPHA:276575
Autosomal Dominant Hyperinsulinism Due To Kir6.2 Deficiency	Pallor	ORPHA:276580
Hyperinsulinism Due To Hnf1A Deficiency	Pallor	ORPHA:324575
Renal Tubular Acidosis, Distal, 4, With Hemolytic Anemia	Short stature, Pallor	OMIM:611590
Evans Syndrome	Pallor, Petechiae	ORPHA:1959
Myopathic Ehlers-Danlos Syndrome	Pallor	ORPHA:536516
Leishmaniasis	Pallor, Skin ulcer	ORPHA:507
Beta-Thalassemia	Pallor, Skin ulcer	ORPHA:848
Myopathy, Lactic Acidosis, And Sideroblastic Anemia 1	Delayed puberty, Pallor, Growth delay	OMIM:600462
Pyruvate Kinase Deficiency Of Red Cells	Intrauterine growth retardation, Pallor	OMIM:266200
Dravet Syndrome	Pallor	ORPHA:33069
Irida Syndrome	Pallor	ORPHA:209981
Myelofibrosis	Purpura, Pallor	OMIM:254450
Primary Myelofibrosis	Purpura, Pallor, Petechiae, Ecchymosis	ORPHA:824
Hb Bart'S Hydrops Fetalis	Pallor	ORPHA:163596
Non-Functioning Paraganglioma	Pallor	ORPHA:94080
Kcnq2-Related Epileptic Encephalopathy	Facial erythema, Pallor	ORPHA:439218
Megaloblastic Anemia Due To Dihydrofolate Reductase Deficiency	Pallor	OMIM:613839
Severe Congenital Hypochromic Anemia With Ringed Sideroblasts	Cafe-au-lait spot, Pallor, Growth delay	ORPHA:300298
Lipodystrophy, Familial Partial, Type 3	Maternal diabetes, Hyperinsulinemia, Hyperglycemia, Type II diabetes mellitus, Insulin resistance...	OMIM:604367
Familial Renal Glucosuria	Abnormal oral glucose tolerance, Insulin resistance, Hyperglycemia, Glycosuria	ORPHA:69076
Drug-Induced Autoimmune Hemolytic Anemia	Pallor	ORPHA:90037
Mody	Neonatal hypoglycemia, Glycosuria, Abnormal oral glucose tolerance, Hyperglycemia, Transient neon...	ORPHA:552
Deafness-Lymphedema-Leukemia Syndrome	Pallor	ORPHA:3226
Cold Agglutinin Disease	Pallor	ORPHA:56425
Acquired Idiopathic Sideroblastic Anemia	Pallor	ORPHA:75564
Autoimmune Hemolytic Anemia	Pallor	ORPHA:98375
3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency	Pallor	OMIM:246450
Mixed-Type Autoimmune Hemolytic Anemia	Pallor	ORPHA:90036
Dominant Beta-Thalassemia	Delayed puberty, Hyperpigmentation of the skin, Growth delay, Pallor, Skin ulcer	ORPHA:231226
Retinitis Pigmentosa 75	Pallor	OMIM:617023
Anemia, Sideroblastic, 1	Anemic pallor	OMIM:300751
6-Pyruvoyl-Tetrahydropterin Synthase Deficiency	Pallor	ORPHA:13
Congenital Dyserythropoietic Anemia Type Iii	Short stature, Pallor	ORPHA:98870
Myopathy, Mitochondrial, And Ataxia	Short stature, Pallor, Growth delay	OMIM:617675
Rheumatic Fever	Erythema, Pallor	ORPHA:3099
Idiopathic Pulmonary Hemosiderosis	Pallor	ORPHA:99931
Congenital Hyperinsulinism Due To Hnf4A Deficiency	Pallor	ORPHA:263455
American Trypanosomiasis	Pallor	ORPHA:3386
Beta-Thalassemia Major	Delayed puberty, Hyperpigmentation of the skin, Growth delay, Pallor, Skin ulcer	ORPHA:231214
Cone-Rod Dystrophy 8	Pallor	OMIM:605549
Tay-Sachs Disease	Pallor	OMIM:272800
Elliptocytosis 1	Pallor	OMIM:611804
Autoimmune Hemolytic Anemia, Warm Type	Pallor	ORPHA:90033
Hereditary Spherocytosis	Pallor, Skin ulcer, Growth delay	ORPHA:822
Fanconi Anemia, Complementation Group C	Anemic pallor, Cafe-au-lait spot, Short stature, Intrauterine growth retardation, Hyperpigmentati...	OMIM:227645
Senior-Loken Syndrome 8	Pallor	OMIM:616307
Incontinentia Pigmenti	Short stature, Erythema, Pallor, Abnormality of skin pigmentation	OMIM:308300
Fanconi Anemia, Complementation Group E	Cafe-au-lait spot, Hyperpigmentation of the skin, Anemic pallor, Short stature	OMIM:600901
Beta-Thalassemia Intermedia	Pallor, Skin ulcer	ORPHA:231222
Plummer-Vinson Syndrome	Pallor	ORPHA:54028
Letterer-Siwe Disease	Pallor	OMIM:246400
Sepsis In Premature Infants	Purpura, Pallor, Petechiae	ORPHA:90051
Fanconi Anemia, Complementation Group A	Cafe-au-lait spot, Anemic pallor, Short stature, Abnormality of skin pigmentation	OMIM:227650
Childhood Absence Epilepsy	Pallor	ORPHA:64280
Fructose-1,6-Bisphosphatase Deficiency	Pallor	ORPHA:348
Hereditary Folate Malabsorption	Pallor	ORPHA:90045
Rare Circulatory System Disease	Pallor	ORPHA:98028
Sporadic Pheochromocytoma/Secreting Paraganglioma	Pallor	ORPHA:276621
Beta-Ketothiolase Deficiency	Pallor	ORPHA:134
Waldenström Macroglobulinemia	Purpura, Pallor	ORPHA:33226
Severe Combined Immunodeficiency Due To Complete Rag1/2 Deficiency	Pallor	ORPHA:331206
Prolactinoma	Delayed puberty, Pallor	ORPHA:2965
Non-Functioning Pituitary Adenoma	Pallor	ORPHA:91349
Imerslund-Gräsbeck Syndrome	Pallor	ORPHA:35858
Diamond-Blackfan Anemia 1	Short stature, Spina bifida occulta, Pallor, Intrauterine growth retardation	OMIM:105650
Aregenerative Anemia	Pallor	ORPHA:101096
Adenohypophysitis	Pallor	ORPHA:95512
Dehydrated Hereditary Stomatocytosis 1 With Or Without Pseudohyperkalemia And/Or Perinatal Edema	Pallor	OMIM:194380
3-Hydroxy-3-Methylglutaric Aciduria	Pallor	ORPHA:20
Pituitary Apoplexy	Pallor	ORPHA:95613
Panhypophysitis	Pallor	ORPHA:95513
Generalized Juvenile Polyposis/Juvenile Polyposis Coli	Anemic pallor, Growth delay	ORPHA:329971
Anemia, Nonspherocytic Hemolytic, Due To G6Pd Deficiency	Pallor	OMIM:300908
Sheehan Syndrome	Dry skin, Pallor	ORPHA:91355
Systemic Mastocytosis With Associated Hematologic Neoplasm	Pallor	ORPHA:98849
Retinitis Pigmentosa And Erythrocytic Microcytosis	Pallor	OMIM:616959
Hereditary Pheochromocytoma-Paraganglioma	Pallor	ORPHA:29072
Fumarase Deficiency	Pallor	OMIM:606812
Refractory Anemia With Excess Blasts	Anemic pallor	ORPHA:86839
Fanconi Anemia, Complementation Group D2	Cafe-au-lait spot, Anemic pallor, Short stature, Abnormality of skin pigmentation	OMIM:227646
Alternating Hemiplegia Of Childhood	Pallor	ORPHA:2131
Degcags Syndrome	Hypopigmentation of the skin, Intrauterine growth retardation, Pallor, Abnormality of skin pigmen...	OMIM:619488
Pearson Marrow-Pancreas Syndrome	Erythema, Pallor	OMIM:557000
Esophageal Atresia	Pallor, Growth delay	ORPHA:1199
Abdominal Obesity-Metabolic Syndrome 3	Hyperglycemia, Type II diabetes mellitus	OMIM:615812
Histiocytoid Cardiomyopathy	Pallor	ORPHA:137675
Tsh-Secreting Pituitary Adenoma	Delayed puberty, Pallor	ORPHA:91347
Idiopathic Hypereosinophilic Syndrome	Pallor	ORPHA:3260
Diamond-Blackfan Anemia	Short stature, Pallor, Growth delay	ORPHA:124
Autosomal Recessive Malignant Osteopetrosis	Pallor, Growth delay	ORPHA:667
Multiple Endocrine Neoplasia Type 2	Pallor	ORPHA:653
Infection-Related Hemolytic Uremic Syndrome	Pallor	ORPHA:544482
Von Hippel-Lindau Disease	Pallor	ORPHA:892
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain And Eye Anomalies), Type A, 3	Pallor	OMIM:253280
Goodpasture Syndrome	Pallor	OMIM:233450
Congenital Total Pulmonary Venous Return Anomaly	Pallor	ORPHA:99125

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Cox7c

This gene doesn't have any significant Histopathology hits. Please click here to see the raw data.

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Cox7c.

There are 1 publication which use IMPC produced mice or data.

Title	Journal	IMPC Allele	PubMed ID
Pitx2 maintains mitochondrial function during regeneration to prevent myocardial fat deposition.	Development (Cambridge, England) (September 2018)	Cox7c^{tm1b(KOMP)Mbp}	30143541

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele	Allele Type	Produced
Cox7c^{tm1a(KOMP)Mbp}	KO first allele (reporter-tagged insertion with conditional potential)	Mice, Targeting vectors, ES Cells
Cox7c^{tm1b(KOMP)Mbp}	Reporter-tagged deletion allele (with selection cassette)	Mice

Sequence

Guides

Sequence	Guide sequence	pam	chr	start	stop	strand	Genome build	gRNA Concentration	Truncated Guide	Reversed	Sanger service	Guide format	Guide source

Nucleases

Nuclease type	Nuclease class

Genotype primers

Sequence	Name

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter