Progress in biomedical research depends on more than innovation — it relies on reproducibility, transparency, and shared access to reliable research tools and methods. The Mutant Mouse Resource and Research Centers (MMRRC) were established to meet that need, serving as a national network dedicated to preserving, characterizing, and distributing scientifically valuable mouse models for the global research community.
Funded by the National Institutes of Health (NIH), the MMRRC acts as a vital bridge between discovery and dissemination. Investigators contribute new genetically engineered and mutant mouse lines to the repository, where they are archived, validated, and maintained under standardized conditions to ensure consistency across studies. This rigorous stewardship enables researchers everywhere to reproduce findings, explore disease mechanisms, and accelerate the development of new therapies with confidence in the quality and integrity of the models they use.
The MMRRC collection supports investigations across nearly every area of biomedical science — from neurodegeneration and immunology to metabolism and developmental biology. Each newly added strain expands the possibilities for insight, representing years of collaborative effort within the scientific community.
To help investigators stay informed, the MMRRC provides a regularly updated newsletter highlighting newly available lines, featured research, and ongoing developments across the consortium. Researchers can subscribe directly on the front page of MMRRC.org to receive updates and ensure access to emerging tools that can advance their work.
By maintaining open access to these critical resources, the MMRRC continues to uphold one of the central principles of science — that discovery grows stronger when knowledge and tools are shared.