Eye Morphology: Images Ophthalmoscopy

WT Images

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: LEFT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia ; LEFT EYE: A little bit of Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia; LEFT EYE: Slight opacity on lens, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Severe Rd8; LEFT EYE: Slight lens opacity, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

Mutant Images

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; LEFT EYE: Slight rd8, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia; LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract; retina no data.; LEFT EYE: Some lens opacity (difficult to focus). Hyaloid present. Severe rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus). Hyaloid present. Severe rd8.,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract; retina no data.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present; LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia; LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia; LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia; LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; LEFT EYE: Slight rd8, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; RIGHT EYE:

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia; LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity ; LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; LEFT EYE: Slight rd8, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract; retina no data.; LEFT EYE: Some lens opacity (difficult to focus). Hyaloid present. Severe rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus). Hyaloid present. Severe rd8.,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract; retina no data.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity ; LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; RIGHT EYE:

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia; LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract; retina no data.; LEFT EYE: Some lens opacity (difficult to focus). Hyaloid present. Severe rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus). Hyaloid present. Severe rd8.,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract; retina no data.

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present; LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present; LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present; LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity ; LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; LEFT EYE: Slight rd8, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia; LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity ; LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; LEFT EYE: Slight rd8, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present; LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract; retina no data.; LEFT EYE: Some lens opacity (difficult to focus). Hyaloid present. Severe rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus). Hyaloid present. Severe rd8.,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract; retina no data.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; RIGHT EYE:

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; LEFT EYE: Slight lens opacity. Hyaloid present. Some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, very slight hemorrhage; RIGHT EYE: Some lens opacity, crystallized debris. Blood vessel early branching. Slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present; LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; LEFT EYE: Slight corneal opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8, some dysplasia.; RIGHT EYE: Blood vessel early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present; LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Severe rd8, small hyaloid present

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe cataract; retina no data.; LEFT EYE: Some lens opacity (difficult to focus). Hyaloid present. Severe rd8.,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus). Hyaloid present. Severe rd8.,
Ophthalmoscope Observation: RIGHT EYE: Severe cataract; retina no data.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight rd8, hemorrhaging and lens opacity.; RIGHT EYE: Some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity ; LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; LEFT EYE: Slight rd8 and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes slight hemorrhaging.; RIGHT EYE: Small hyaloid present. Some debris (difficult to focus). Some rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Slight rd8, some dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Some rd8, some dysplasia,

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and some lens opacity (difficult to image and focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Very slight rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; LEFT EYE: Slight rd8, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia ; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some dysplasia, slight rd8, hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8

58 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia; LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Some corneal and lens opacity (difficult to focus), bright cotton patches, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (restless mouse-difficult to image and focus).; RIGHT EYE:

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, blood vessel slightly early branching, some rd8; RIGHT EYE: Bright cotton debris, some dysplasia

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Very slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Slight dysplasia. Blood vessel slightly early branching

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; LEFT EYE: slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging and very slight rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; LEFT EYE: Slight rd8. White ring/bright spots around optic nerve and mid top.,
Ophthalmoscope Observation: Both eyes some lens opacity/debris (difficult to image and focus). Slight hemorrhaging ; RIGHT EYE: Hyaloid present. Retina ?pixelated texture??

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity ; LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some rd8, white cotton debris and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Slight rd8 and lens opacity

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; LEFT EYE: Some rd8 and dysplasia. Slight debris.,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus).; RIGHT EYE: Hyaloid present. Moderate rd8 and slight dysplasia.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.; LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and lens opacity (difficult to focus). Blood vessel early branching,
Ophthalmoscope Observation: RIGHT EYE: Small hyaloid present and some debris (difficult to image and focus). Blood vessel slightly early branching. Very slight rd8.

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; LEFT EYE: Slight rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia; RIGHT EYE: Slight corneal opacity, moderate rd8

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Some lens opacity (difficult to focus).

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity. Slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity. Some dysplasia, slight hemorrhage

57 weeks old

Polr3dem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to image and focus). Blood vessel slightly early branching; RIGHT EYE: Some rd8 and slight hemorrhaging.

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