Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8; LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; RIGHT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; LEFT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Hard to focus,
Ophthalmoscope Observation: Hard to focus ; LEFT EYE:,
Ophthalmoscope Observation: Hard to focus ; RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: some rd8; LEFT EYE: some rd8,
Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE: some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8; LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; RIGHT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; LEFT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous; LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous; LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Hard to focus,
Ophthalmoscope Observation: Hard to focus ; LEFT EYE:,
Ophthalmoscope Observation: Hard to focus ; RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8; LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; RIGHT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; LEFT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: some rd8; LEFT EYE: some rd8,
Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE: some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Hard to focus,
Ophthalmoscope Observation: Hard to focus ; LEFT EYE:,
Ophthalmoscope Observation: Hard to focus ; RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous; LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous; LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8; LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; RIGHT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; LEFT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Hard to focus,
Ophthalmoscope Observation: Hard to focus ; LEFT EYE:,
Ophthalmoscope Observation: Hard to focus ; RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; RIGHT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; LEFT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; RIGHT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhage ; LEFT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Hard to focus,
Ophthalmoscope Observation: Hard to focus ; LEFT EYE:,
Ophthalmoscope Observation: Hard to focus ; RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight dysplasia and hemorrhaging.; RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE: Two black spots.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE: Two bright white large spots/lesions?

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous; LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small lesion near optic nerve, slight hemorrhaging

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Hard to focus,
Ophthalmoscope Observation: Hard to focus ; LEFT EYE:,
Ophthalmoscope Observation: Hard to focus ; RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, some lens opacity, difficult to focus; RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some rd8, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8; LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: some rd8; LEFT EYE: some rd8,
Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE: some rd8

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: some rd8; LEFT EYE: some rd8,
Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE: some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: some rd8; LEFT EYE: some rd8,
Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE: some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: some rd8; LEFT EYE: some rd8,
Ophthalmoscope Observation: LEFT EYE: some rd8,
Ophthalmoscope Observation: RIGHT EYE: some rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8; LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

14 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8; LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: LEFT EYE: Hyaloid present and some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

15 weeks old

Zc3h12cem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous; LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: LEFT EYE: Some hemorrhage, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight white crystalline in vitreous

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