Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8; LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.; LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus); LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus)

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus); LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus)

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.; LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8; LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; RIGHT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.; LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus); LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus)

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; RIGHT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8; LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8; LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (difficult to focus). Some rd8; RIGHT EYE: Slight lens opacity. Slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; RIGHT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus); LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus)

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE: Hyaloid present, some debris (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus); LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus)

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; RIGHT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus); LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus)

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8; LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus); LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; LEFT EYE: Blood vessel early branching and crossing,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, very slight hemorrhage; RIGHT EYE: Small hyaloid and multiple crystallized debris present (obstructing part of retina, difficult to focus)

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE: Hyaloid present, some debris (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes crystallized debris (obstructing the retina, difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel slightly early branching, slight dysplasia

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; RIGHT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.; LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8; LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes slight rd8, slight dysplasia; RIGHT EYE: Slight lens opacity

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE: Hyaloid present, some debris (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Small crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple small hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE: Hyaloid present, some debris (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8; LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, slight rd8, slight dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Very slight lens opacity, tiny hyaloid, some rd8

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE: Hyaloid present, some debris (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; LEFT EYE: Blood vessel crossing near optic disc and slightly early branching. Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris (difficult to focus). Some rd8, slight hemorrhage, very slight molten patches; RIGHT EYE: Hyaloid present

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris present. Some rd8; RIGHT EYE: Hyaloid present. Blood vessel slightly early branching

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE: Hyaloid present, some debris (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Multiple tiny hyaloid, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, very slight hemorrhage; RIGHT EYE: Tiny hyaloid present, blood vessel early branching and crossing near optic disc

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus). Blood vessel slightly early branching.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Hyaloid present.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; RIGHT EYE: Hyaloid present, some debris (difficult to focus). Slight dysplasia.,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity.; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.; LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight dysplasia ; RIGHT EYE: Slight rd8, slight hemorrhage

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.; LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8 and dysplasia; RIGHT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; RIGHT EYE: Blood vessel early branching. Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity. Crystallized debris. Some rd8; LEFT EYE:

14 weeks old

Kctd3em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.; LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity and debris. Some rd8, slight dysplasia.,
Ophthalmoscope Observation: RIGHT EYE: Some corneal opacity/cataract. Very large hyaloid present, crystallized debris (retinal obstruction, limited data). Blood vessel crossing.

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