Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

15 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present ; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage ; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching ; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; RIGHT EYE: Black spot on retina,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; LEFT EYE:

15 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present ; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage ; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage ; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching ; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching

15 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present ; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching ; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina ; LEFT EYE: Some lens opacity, crystallized debris, blood vessel crossing and slightly branching, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, crystallized debris, blood vessel crossing and slightly branching, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage ; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

15 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present ; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; RIGHT EYE: Black spot on retina,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; LEFT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina ; LEFT EYE: Some lens opacity, crystallized debris, blood vessel crossing and slightly branching, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, crystallized debris, blood vessel crossing and slightly branching, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage ; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; LEFT EYE: Blood vessel slightly early branching, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, abnormal retinal pigmentation; RIGHT EYE: Blood vessel early branching and crossing, some hemorrhage

15 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present ; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina ; LEFT EYE: Some lens opacity, crystallized debris, blood vessel crossing and slightly branching, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, crystallized debris, blood vessel crossing and slightly branching, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; LEFT EYE: Blood vessel early branching. Some rd8,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid (obstructing part of optic disc), slight dysplasia; RIGHT EYE: Blood vessel crossing. Slight rd8

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; RIGHT EYE: Black spot on retina,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; LEFT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage ; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching ; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina ; LEFT EYE: Some lens opacity, crystallized debris, blood vessel crossing and slightly branching, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity, crystallized debris, blood vessel crossing and slightly branching, some rd8, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Severe corneal opacity, no data retina

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching ; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching

15 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present ; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, some rd8; RIGHT EYE: Blood vessel slightly early branching. Some hemorrhage,

15 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present ; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight rd8, moderate hemorrhaging, some lens opacity and slight dysplasia.; RIGHT EYE: Hyaloid present

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage ; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching. Abnormal pigmentation surround optic disc,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; LEFT EYE: Tiny hyaloid. Some hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity. Some rd8; RIGHT EYE: Hyaloid. Slight hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; RIGHT EYE: Black spot on retina,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; LEFT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing the optic disc, blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Hyaloid (obstructing part of retina). Some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation

15 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Hyaloid present, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Large hyaloid obstructing part of retina and optic disc (difficult to focus), blood vessel early branching and crossing

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; LEFT EYE: Blood vessel early branching, slight dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), hyaloid present, slight rd8; RIGHT EYE: Blood vessel slightly early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), blood vessel slightly early branching, slight rd8, slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, hyaloid present, blood vessel early branching, some rd8, some hemorrhage

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching ; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; RIGHT EYE: Black spot on retina,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; LEFT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; LEFT EYE: Some lens opacity. Hyaloid present. Blood vessel crossing. Abnormal pigmentation around optic disc,
Ophthalmoscope Observation: Both eyes difficult to focus. Blood vessel early branching. Some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Slight lens opacity. Small crystallized debris. Blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp hemizygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching ; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; LEFT EYE: Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus). Some rd8; RIGHT EYE: Big hyaloid (obstructing part of retina and optic disc), blood vessel early branching

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; RIGHT EYE: Black spot on retina,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus), slight rd8, slight hemorrhage, very slight dysplasia; LEFT EYE:

14 weeks old

Bcorl1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; LEFT EYE: Some lens opacity (difficult to focus), hyaloid present,
Ophthalmoscope Observation: Both eyes crystallized debris, slight rd8, slight hemorrhage; RIGHT EYE: Slight lens opacity (difficult to focus), crystallized debris connecting to optic disc, blood vessel early branching, abnormal retinal pigmentation

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