Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris (difficult to focus), hyaloid present,,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris (difficult to focus), hyaloid present,,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris (difficult to focus), hyaloid present,,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia; RIGHT EYE: Some rd8, slight hemorrhage, slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes slight dysplasia; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; RIGHT EYE:

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia; RIGHT EYE: Some rd8, slight hemorrhage, slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes slight dysplasia; LEFT EYE:

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris (difficult to focus), hyaloid present,,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; RIGHT EYE:

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris (difficult to focus), hyaloid present,,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris (difficult to focus), hyaloid present,,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia; RIGHT EYE: Some rd8, slight hemorrhage, slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes slight dysplasia; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris (difficult to focus), hyaloid present,,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia; RIGHT EYE: Some rd8, slight hemorrhage, slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes slight dysplasia; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE:

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, difficult to focus and image,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid and crystallized debris present, difficult to focus and image. Slight hemorrhaging

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Blood vessel crossing, slight hemorrhage, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Crystallized debris, some dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Hyaloid present; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Moderate dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, some crystallized debris difficult to focus, slight dysplasia

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; RIGHT EYE:

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia; RIGHT EYE: Some rd8, slight hemorrhage, slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes slight dysplasia; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; LEFT EYE:,
Ophthalmoscope Observation: Both eyes hyaloid present and some dysplasia; RIGHT EYE:

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; LEFT EYE:

15 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia; RIGHT EYE: Some rd8, slight hemorrhage, slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes slight dysplasia; LEFT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes molten patches, some rd8, slight dysplasia; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; LEFT EYE: Slight lens opacity, moderate rd8, slight molten patches,
Ophthalmoscope Observation: Both eyes slight hemorrhaging; RIGHT EYE: Some rd8, slight dysplasia, very slight molten patches

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Dymem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia and some hemorrhaging; RIGHT EYE:

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