Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some bright white patches on retina; RIGHT EYE: Slight lens opacity, slight hemorrhage ; LEFT EYE: Some lens opacity, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes some bright white patches on retina

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage; RIGHT EYE: Slight corneal opacity, some lens opacity, crystallized debris, early blood vessel branching; LEFT EYE: Slight lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8 ; RIGHT EYE: Tiny hyaloid, very slight hemorrhage ; LEFT EYE: Some opacity (difficult to focus), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching, slight lens opacity. ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8 ; RIGHT EYE: Tiny hyaloid, very slight hemorrhage ; LEFT EYE: Some opacity (difficult to focus), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE: Some crystallized debris (difficult to focus), slightly early blood vessel branching; LEFT EYE: Vessel connecting to crystal debris, slight hemorrhage, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Small lesions, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching; LEFT EYE: Slight dysplasia, crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight corneal opacity, hyaloid present, large crystallized debris (difficult to focus), some lens opacity; LEFT EYE: Slight lens opacity, slight dysplasia, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some bright white patches on retina; RIGHT EYE: Slight lens opacity, slight hemorrhage ; LEFT EYE: Some lens opacity, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes some bright white patches on retina

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity; RIGHT EYE: Small hyaloid present, some dysplasia, slight hemorrhage; LEFT EYE: Multiple hyaloid different lens layer, slight dysplasia, slight molten patches,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, some rd8, slight dysplasia; LEFT EYE: Multiple bright dysplasia patches, bright crystallized, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity; RIGHT EYE: Small hyaloid present, some dysplasia, slight hemorrhage; LEFT EYE: Multiple hyaloid different lens layer, slight dysplasia, slight molten patches,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching, slight lens opacity. ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, slight lens opacity, very slight hemorrhage ; LEFT EYE: Small hyaloid present, some lens opacity,
Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching; LEFT EYE: Slight dysplasia, crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity; RIGHT EYE: Small hyaloid present, some dysplasia, slight hemorrhage; LEFT EYE: Multiple hyaloid different lens layer, slight dysplasia, slight molten patches,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight corneal opacity, hyaloid present, large crystallized debris (difficult to focus), some lens opacity; LEFT EYE: Slight lens opacity, slight dysplasia, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE: Some crystallized debris (difficult to focus), slightly early blood vessel branching; LEFT EYE: Vessel connecting to crystal debris, slight hemorrhage, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches ; RIGHT EYE: Early blood vessel branching, lesion present; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, some rd8, slight dysplasia; LEFT EYE: Multiple bright dysplasia patches, bright crystallized, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE: Some crystallized debris (difficult to focus), slightly early blood vessel branching; LEFT EYE: Vessel connecting to crystal debris, slight hemorrhage, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches ; RIGHT EYE: Early blood vessel branching, lesion present; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity; RIGHT EYE: Small hyaloid present, some dysplasia, slight hemorrhage; LEFT EYE: Multiple hyaloid different lens layer, slight dysplasia, slight molten patches,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, slight lens opacity, very slight hemorrhage ; LEFT EYE: Small hyaloid present, some lens opacity,
Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some bright white patches on retina; RIGHT EYE: Slight lens opacity, slight hemorrhage ; LEFT EYE: Some lens opacity, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes some bright white patches on retina

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity; RIGHT EYE: Small hyaloid present, some dysplasia, slight hemorrhage; LEFT EYE: Multiple hyaloid different lens layer, slight dysplasia, slight molten patches,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage; RIGHT EYE: Slight corneal opacity, some lens opacity, crystallized debris, early blood vessel branching; LEFT EYE: Slight lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some bright white patches on retina; RIGHT EYE: Slight lens opacity, slight hemorrhage ; LEFT EYE: Some lens opacity, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes some bright white patches on retina

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, some rd8, slight dysplasia; LEFT EYE: Multiple bright dysplasia patches, bright crystallized, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Small lesions, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight corneal opacity, hyaloid present, large crystallized debris (difficult to focus), some lens opacity; LEFT EYE: Slight lens opacity, slight dysplasia, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight corneal opacity, hyaloid present, large crystallized debris (difficult to focus), some lens opacity; LEFT EYE: Slight lens opacity, slight dysplasia, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching; LEFT EYE: Slight dysplasia, crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches ; RIGHT EYE: Early blood vessel branching, lesion present; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight hemorrhage, small lesions on retina; LEFT EYE: Some lens opacity, white lesions on retina, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight corneal opacity, hyaloid present, large crystallized debris (difficult to focus), some lens opacity; LEFT EYE: Slight lens opacity, slight dysplasia, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches ; RIGHT EYE: Early blood vessel branching, lesion present; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight corneal opacity, hyaloid present, large crystallized debris (difficult to focus), some lens opacity; LEFT EYE: Slight lens opacity, slight dysplasia, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8 ; RIGHT EYE: Tiny hyaloid, slight lens opacity, some hemorrhage; LEFT EYE: Some lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some bright white patches on retina; RIGHT EYE: Slight lens opacity, slight hemorrhage ; LEFT EYE: Some lens opacity, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes some bright white patches on retina

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight hemorrhage, small lesions on retina; LEFT EYE: Some lens opacity, white lesions on retina, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching; LEFT EYE: Slight dysplasia, crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8 ; RIGHT EYE: Tiny hyaloid, slight lens opacity, some hemorrhage; LEFT EYE: Some lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching; LEFT EYE: Slight dysplasia, crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Small lesions, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8 ; RIGHT EYE: Tiny hyaloid, very slight hemorrhage ; LEFT EYE: Some opacity (difficult to focus), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8 ; RIGHT EYE: Tiny hyaloid, very slight hemorrhage ; LEFT EYE: Some opacity (difficult to focus), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage; RIGHT EYE: Slight corneal opacity, some lens opacity, crystallized debris, early blood vessel branching; LEFT EYE: Slight lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight hemorrhage, small lesions on retina; LEFT EYE: Some lens opacity, white lesions on retina, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity; RIGHT EYE: Small hyaloid present, some dysplasia, slight hemorrhage; LEFT EYE: Multiple hyaloid different lens layer, slight dysplasia, slight molten patches,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching, slight lens opacity. ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight hemorrhage, small lesions on retina; LEFT EYE: Some lens opacity, white lesions on retina, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE: Some crystallized debris (difficult to focus), slightly early blood vessel branching; LEFT EYE: Vessel connecting to crystal debris, slight hemorrhage, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage; RIGHT EYE: Slight corneal opacity, some lens opacity, crystallized debris, early blood vessel branching; LEFT EYE: Slight lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some hemorrhage

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8 ; RIGHT EYE: Tiny hyaloid, slight lens opacity, some hemorrhage; LEFT EYE: Some lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, slight lens opacity, very slight hemorrhage ; LEFT EYE: Small hyaloid present, some lens opacity,
Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8 ; RIGHT EYE: Tiny hyaloid, slight lens opacity, some hemorrhage; LEFT EYE: Some lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity; RIGHT EYE: Small hyaloid present, some dysplasia, slight hemorrhage; LEFT EYE: Multiple hyaloid different lens layer, slight dysplasia, slight molten patches,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching, slight lens opacity. ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, slight lens opacity, very slight hemorrhage ; LEFT EYE: Small hyaloid present, some lens opacity,
Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, slight lens opacity, very slight hemorrhage ; LEFT EYE: Small hyaloid present, some lens opacity,
Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Small lesions, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8 ; RIGHT EYE: Tiny hyaloid, slight lens opacity, some hemorrhage; LEFT EYE: Some lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage; RIGHT EYE: Slight corneal opacity, some lens opacity, crystallized debris, early blood vessel branching; LEFT EYE: Slight lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, some rd8, slight dysplasia; LEFT EYE: Multiple bright dysplasia patches, bright crystallized, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Small lesions, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, slight lens opacity, very slight hemorrhage ; LEFT EYE: Small hyaloid present, some lens opacity,
Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, some rd8, slight dysplasia; LEFT EYE: Multiple bright dysplasia patches, bright crystallized, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity; RIGHT EYE: Small hyaloid present, some dysplasia, slight hemorrhage; LEFT EYE: Multiple hyaloid different lens layer, slight dysplasia, slight molten patches,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching, slight lens opacity. ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some bright white patches on retina; RIGHT EYE: Slight lens opacity, slight hemorrhage ; LEFT EYE: Some lens opacity, very slight hemorrhage,
Ophthalmoscope Observation: Both eyes some bright white patches on retina

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE: Some crystallized debris (difficult to focus), slightly early blood vessel branching; LEFT EYE: Vessel connecting to crystal debris, slight hemorrhage, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE: Some crystallized debris (difficult to focus), slightly early blood vessel branching; LEFT EYE: Vessel connecting to crystal debris, slight hemorrhage, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight corneal opacity, hyaloid present, large crystallized debris (difficult to focus), some lens opacity; LEFT EYE: Slight lens opacity, slight dysplasia, blood vessel crossing and early branching,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8 ; RIGHT EYE: Tiny hyaloid, very slight hemorrhage ; LEFT EYE: Some opacity (difficult to focus), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Small lesions, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia and hemorrhaging.

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8 ; RIGHT EYE: Tiny hyaloid, very slight hemorrhage ; LEFT EYE: Some opacity (difficult to focus), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage; RIGHT EYE: Slight corneal opacity, some lens opacity, crystallized debris, early blood vessel branching; LEFT EYE: Slight lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching; LEFT EYE: Slight dysplasia, crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, blood vessel crossing and early branching

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8 ; RIGHT EYE: Tiny hyaloid, slight lens opacity, some hemorrhage; LEFT EYE: Some lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight hemorrhage, small lesions on retina; LEFT EYE: Some lens opacity, white lesions on retina, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8 ; RIGHT EYE: Tiny hyaloid, very slight hemorrhage ; LEFT EYE: Some opacity (difficult to focus), slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, slightly early blood vessel branching, some rd8

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity; RIGHT EYE: Small hyaloid present, some dysplasia, slight hemorrhage; LEFT EYE: Multiple hyaloid different lens layer, slight dysplasia, slight molten patches,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some rd8, slight lens opacity

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches ; RIGHT EYE: Early blood vessel branching, lesion present; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches ; RIGHT EYE: Early blood vessel branching, lesion present; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, some bright dysplasia patches

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, some rd8, slight dysplasia; LEFT EYE: Multiple bright dysplasia patches, bright crystallized, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight lesions present on retina, some rd8, slight hemorrhage

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching, slight lens opacity. ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage; RIGHT EYE: Slight corneal opacity, some lens opacity, crystallized debris, early blood vessel branching; LEFT EYE: Slight lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some hemorrhage

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, slight lens opacity, very slight hemorrhage ; LEFT EYE: Small hyaloid present, some lens opacity,
Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight hemorrhage, small lesions on retina; LEFT EYE: Some lens opacity, white lesions on retina, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE: Some crystallized debris (difficult to focus), slightly early blood vessel branching; LEFT EYE: Vessel connecting to crystal debris, slight hemorrhage, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, some rd8, slight dysplasia; LEFT EYE: Multiple bright dysplasia patches, bright crystallized, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity

14 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia ; RIGHT EYE: Hyaloid present, slight lens opacity, very slight hemorrhage ; LEFT EYE: Small hyaloid present, some lens opacity,
Ophthalmoscope Observation: Both eyes early blood vessel, some rd8, slight dysplasia

15 weeks old

Ubr7em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8 ; RIGHT EYE: Tiny hyaloid, slight lens opacity, some hemorrhage; LEFT EYE: Some lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes eyes some lesions present, some rd8

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