Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity, slightly early blood braching; LEFT EYE: Slight lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching; RIGHT EYE: Slight debris, some dysplasia; LEFT EYE: Blood vessel crossing, moderate/severe dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage; RIGHT EYE: Early blood vessel branching; LEFT EYE: Small hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity and debris (difficult to focus), small lesion?, slight early blood vessel branching; LEFT EYE: Small hyaloid, some dysplasia, early blood vessel branching, Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia; RIGHT EYE: Difficult to focus, some lens opacity; LEFT EYE: Blood vessel crossing and slightly early branching, slight lens opacity,
Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.; RIGHT EYE: Vessel crossing at optic nerve, slight debris (difficult to focus), slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), tiny crystallized debris, slight dysplasia, very slight molten patches ; LEFT EYE: Slight lens opacity, some debris, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging; RIGHT EYE: Some lens opacity, slight debris, slight dysplasia; LEFT EYE: Blood vessel slightly early branching, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity; RIGHT EYE: Blood vessel crossing, slight debris,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity; RIGHT EYE: Slight debris, bood vessel crossing and slightly early branching; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching; RIGHT EYE: Slight debris, some dysplasia; LEFT EYE: Blood vessel crossing, moderate/severe dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity; RIGHT EYE: Blood vessel crossing, slight debris,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching; RIGHT EYE: Slight debris, some dysplasia; LEFT EYE: Blood vessel crossing, moderate/severe dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight debris, slight dysplasia ; LEFT EYE: Some dysplasia, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,; RIGHT EYE: Slight lens opacity, small lesion present, early blood vessel branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, some dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity, slightly early blood braching; LEFT EYE: Slight lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage; RIGHT EYE: Early blood vessel branching; LEFT EYE: Small hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present, early blood vessel branching, slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity; RIGHT EYE: Blood vessel crossing, slight debris,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity and debris (difficult to focus), small lesion?, slight early blood vessel branching; LEFT EYE: Small hyaloid, some dysplasia, early blood vessel branching, Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching; RIGHT EYE: Slight debris, some dysplasia; LEFT EYE: Blood vessel crossing, moderate/severe dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.; RIGHT EYE: Hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity; RIGHT EYE: Slight debris, bood vessel crossing and slightly early branching; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight debris, slight dysplasia ; LEFT EYE: Some dysplasia, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.; RIGHT EYE: Vessel crossing at optic nerve, slight debris (difficult to focus), slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage; RIGHT EYE: Early blood vessel branching; LEFT EYE: Small hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight debris, slight dysplasia ; LEFT EYE: Some dysplasia, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,; RIGHT EYE: Slight lens opacity, small lesion present, early blood vessel branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), tiny crystallized debris, slight dysplasia, very slight molten patches ; LEFT EYE: Slight lens opacity, some debris, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching; RIGHT EYE: Slight debris, some dysplasia; LEFT EYE: Blood vessel crossing, moderate/severe dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present, early blood vessel branching, slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,; RIGHT EYE: Slight lens opacity, small lesion present, early blood vessel branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, some dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, some dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity, slightly early blood braching; LEFT EYE: Slight lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present, early blood vessel branching, slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.; RIGHT EYE: Vessel crossing at optic nerve, slight debris (difficult to focus), slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight debris, slight dysplasia ; LEFT EYE: Some dysplasia, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia; RIGHT EYE: Difficult to focus, some lens opacity; LEFT EYE: Blood vessel crossing and slightly early branching, slight lens opacity,
Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.; RIGHT EYE: Vessel crossing at optic nerve, slight debris (difficult to focus), slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present, early blood vessel branching, slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity and debris (difficult to focus), small lesion?, slight early blood vessel branching; LEFT EYE: Small hyaloid, some dysplasia, early blood vessel branching, Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.; RIGHT EYE: Hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.; RIGHT EYE: Hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight debris, slight dysplasia ; LEFT EYE: Some dysplasia, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.; RIGHT EYE: Hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity; RIGHT EYE: Slight debris, bood vessel crossing and slightly early branching; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.; RIGHT EYE: Vessel crossing at optic nerve, slight debris (difficult to focus), slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), tiny crystallized debris, slight dysplasia, very slight molten patches ; LEFT EYE: Slight lens opacity, some debris, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Slight debris, slight dysplasia ; LEFT EYE: Some dysplasia, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity and debris (difficult to focus), small lesion?, slight early blood vessel branching; LEFT EYE: Small hyaloid, some dysplasia, early blood vessel branching, Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity and debris (difficult to focus), small lesion?, slight early blood vessel branching; LEFT EYE: Small hyaloid, some dysplasia, early blood vessel branching, Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity and debris (difficult to focus), small lesion?, slight early blood vessel branching; LEFT EYE: Small hyaloid, some dysplasia, early blood vessel branching, Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity, slightly early blood braching; LEFT EYE: Slight lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity; RIGHT EYE: Blood vessel crossing, slight debris,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), tiny crystallized debris, slight dysplasia, very slight molten patches ; LEFT EYE: Slight lens opacity, some debris, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity; RIGHT EYE: Slight debris, bood vessel crossing and slightly early branching; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.; RIGHT EYE: Hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,; RIGHT EYE: Slight lens opacity, small lesion present, early blood vessel branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.; RIGHT EYE: Hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage; RIGHT EYE: Early blood vessel branching; LEFT EYE: Small hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia; RIGHT EYE: Difficult to focus, some lens opacity; LEFT EYE: Blood vessel crossing and slightly early branching, slight lens opacity,
Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, some dysplasia

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage; RIGHT EYE: Early blood vessel branching; LEFT EYE: Small hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity; RIGHT EYE: Slight debris, bood vessel crossing and slightly early branching; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), tiny crystallized debris, slight dysplasia, very slight molten patches ; LEFT EYE: Slight lens opacity, some debris, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia; RIGHT EYE: Difficult to focus, some lens opacity; LEFT EYE: Blood vessel crossing and slightly early branching, slight lens opacity,
Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, some dysplasia

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity; RIGHT EYE: Blood vessel crossing, slight debris,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity; RIGHT EYE: Blood vessel crossing, slight debris,
Ophthalmoscope Observation: Both eyes some rd8, some dysplasia, some hemorrhaging and slight lens opacity

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage; RIGHT EYE: Early blood vessel branching; LEFT EYE: Small hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage; RIGHT EYE: Early blood vessel branching; LEFT EYE: Small hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some lens opacity, some dysplasia, some rd8, some hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,; RIGHT EYE: Slight lens opacity, small lesion present, early blood vessel branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,; RIGHT EYE: Slight lens opacity, small lesion present, early blood vessel branching; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia,

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging; RIGHT EYE: Some lens opacity, slight debris, slight dysplasia; LEFT EYE: Blood vessel slightly early branching, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present, early blood vessel branching, slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present, early blood vessel branching, slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity; RIGHT EYE: Slight debris, bood vessel crossing and slightly early branching; LEFT EYE: Early blood vessel branching,
Ophthalmoscope Observation: Both eyes eyes some rd8, slight dysplasia, slight hemorrhaging, slight lens opacity

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging; RIGHT EYE: Some lens opacity, slight debris, slight dysplasia; LEFT EYE: Blood vessel slightly early branching, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, some dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching; RIGHT EYE: Slight debris, some dysplasia; LEFT EYE: Blood vessel crossing, moderate/severe dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage, early blood vessel branching

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity (difficult to focus), tiny crystallized debris, slight dysplasia, very slight molten patches ; LEFT EYE: Slight lens opacity, some debris, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia; RIGHT EYE: Difficult to focus, some lens opacity; LEFT EYE: Blood vessel crossing and slightly early branching, slight lens opacity,
Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia; RIGHT EYE: Difficult to focus, some lens opacity; LEFT EYE: Blood vessel crossing and slightly early branching, slight lens opacity,
Ophthalmoscope Observation: Both eyes some bright hemorrhage, some rd8, slight dysplasia

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity and debris (difficult to focus), small lesion?, slight early blood vessel branching; LEFT EYE: Small hyaloid, some dysplasia, early blood vessel branching, Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE: Hyaloid present, early blood vessel branching, slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.; RIGHT EYE: Vessel crossing at optic nerve, slight debris (difficult to focus), slight dysplasia; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes early blood vessel branching, some hemorrhaging, some rd8, slight lens opacity.

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging; RIGHT EYE: Some lens opacity, slight debris, slight dysplasia; LEFT EYE: Blood vessel slightly early branching, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia ; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Restless mouse. Both eyes slight debris, some rd8, early blood vessel branching, slight hemorrhage, slight dysplasia

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging; RIGHT EYE: Some lens opacity, slight debris, slight dysplasia; LEFT EYE: Blood vessel slightly early branching, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity, slightly early blood braching; LEFT EYE: Slight lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

14 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging; RIGHT EYE: Some lens opacity, slight debris, slight dysplasia; LEFT EYE: Blood vessel slightly early branching, some dysplasia, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage ; RIGHT EYE: Some lens opacity, slightly early blood braching; LEFT EYE: Slight lens opacity, blood vessel crossing,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, slight hemorrhage

15 weeks old

Gnb1lem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.; RIGHT EYE: Hyaloid present, blood vessel crossing,
Ophthalmoscope Observation: Both eyes early vessel branching, some rd8, some dysplasia, slight hemorrhaging, slight lens opacity.

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter