Spleen Immunophenotyping: Images associated with FACS analysis
WT Images
15 weeks old
Mature NK cells - % of NK cellls: 79.014
15 weeks old
Resting Treg cells - % of Treg: 58.223
15 weeks old
Conventional DC (cDC) - % of CD45+: 1.509
15 weeks old
Resting CD4- NKT cells - % of CD4- NKT cells: 65.42
15 weeks old
CD11b-low cDC - % of cDC: 44.004
15 weeks old
KLRG1+ CD4+ T helper cells - % of CD45+: 0.16
15 weeks old
Effector gd cells - % of CD45+: 0.504
15 weeks old
Immature NK cells - % of lymphocytes: 0.621
15 weeks old
Total CD4- NKT cells - % of CD45+: 0.33
15 weeks old
CD4+ T helper cells - % of CD4+: 88.702
15 weeks old
B1a cells - % of B cells: 1.383
15 weeks old
Germinal centre B cells - % of CD45+: 0.24
15 weeks old
Marginal zone B cells - % of B2 cells: 6.071
15 weeks old
CD11b-low cDC - % of CD45+: 0.664
15 weeks old
Macrophages - % of CD45+: 0.616
15 weeks old
Effector Treg cells - % of CD45+: 0.617
15 weeks old
Effector CD8+ T cells - % of CD8+: 6.136
15 weeks old
Ly6C+ NKT cells - % of lymphocytes: 0.53
15 weeks old
Mature NK cells - % of lymphocytes: 2.337
15 weeks old
Naive CD8+ T cells - % of CD45+: 5.623
15 weeks old
Plasma cells - % of CD45+: 0.106
15 weeks old
Effector NK cells - % of CD45+: 0.361
15 weeks old
B2 t1 + t2 cells - % of B2 cells: 9.78
15 weeks old
Resting CD4+ T helper cells - % of CD4+ T helper cells: 70.523
15 weeks old
KLRG1+ Treg cells - % of CD45+: 0.131
15 weeks old
CD5+ gd T cells - % of CD45+: 0.499
15 weeks old
Effector CD4- NKT cells - % of CD4- NKT cells: 34.58
15 weeks old
CD11b-high cDC - % of CD45+: 0.84
15 weeks old
KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells: 1.394
15 weeks old
Total ab T cells - % of CD45+: 22.716
15 weeks old
Effector CD8+ T cells - % of CD45+: 0.591
15 weeks old
Effector CD4+ T helper cells - % of CD45+: 3.361
15 weeks old
Total gd T cells - % of CD45+: 1.223
15 weeks old
Plasma cells - % of B2 cells: 0.169
15 weeks old
Resting CD4+ NKT cells - % of CD4+ NKT cells: 16.46
15 weeks old
Plasmacytoid DC - % of DC: 19.041
15 weeks old
Total CD4+ T cells - % of CD45+: 12.97
15 weeks old
Effector gd T cells - % of gd T cells: 41.226
15 weeks old
Resting CD8+ T cells - % of CD45+: 3.147
15 weeks old
Total CD8+ T cells - % of ab T cells: 42.423
15 weeks old
Effector CD4+ NKT cells - % of CD45+: 0.268
15 weeks old
Marginal zone precursor B cells - % of CD45+: 2.948
15 weeks old
CD103+ CD11b-low cDC - % of CD45+: 0.064
15 weeks old
Resting CD8+ T cells - % of CD8+: 32.653
15 weeks old
Total B2 cells - % of B cells: 98.617
15 weeks old
Resting NK cells - % of CD45+: 2.079
15 weeks old
Total CD4+ T cells - % of ab T cells: 57.099
15 weeks old
Total Treg cells - % of CD45+: 1.486
15 weeks old
Immature NK cells - % of NK cells: 20.986
15 weeks old
Ly6C+ immature NK cells - % of lymphocytes: 0.09
Mutant Images
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Resting Treg cells - % of CD45+: 0.623
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-low cDC - % of cDC: 52.008
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Total DC - % of CD45+: 0.685
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of CD45+: 0.309
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Conventional DC (cDC) - % of DC: 93.495
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-low cDC - % of cDC: 59.301
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of cDC: 40.462
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of cDC: 39.552
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Resting Treg cells - % of CD45+: 0.586
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of DC: 9.148
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of NK cells: 18.364
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Total DC - % of CD45+: 1.261
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of DC: 11.436
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of CD45+: 0.436
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Resting Treg cells - % of CD45+: 0.449
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Total DC - % of CD45+: 1.736
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Conventional DC (cDC) - % of DC: 85.991
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of lymphocytes: 0.564
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of DC: 8.483
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Conventional DC (cDC) - % of DC: 88.564
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-low cDC - % of cDC: 60.175
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of cDC: 36.818
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of DC: 14.009
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of lymphocytes: 0.538
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of lymphocytes: 0.694
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-low cDC - % of cDC: 56.099
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Mature NK cells - % of NK cellls: 84.947
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of cDC: 37.956
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of lymphocytes: 0.608
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of NK cells: 19.54
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Mature NK cells - % of NK cellls: 81.636
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.111
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of CD45+: 0.264
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of cDC: 47.786
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.1
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of NK cells: 19.763
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Resting Treg cells - % of CD45+: 0.662
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of CD45+: 0.616
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of DC: 13.42
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of cDC: 43.516
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.107
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Resting Treg cells - % of CD45+: 0.442
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of NK cells: 15.053
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of DC: 6.505
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Conventional DC (cDC) - % of DC: 90.852
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Total DC - % of CD45+: 0.75
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of NK cells: 17.099
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Total DC - % of CD45+: 0.748
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Conventional DC (cDC) - % of DC: 86.58
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of CD45+: 0.261
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Total DC - % of CD45+: 1.213
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.105
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Mature NK cells - % of NK cellls: 82.901
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of lymphocytes: 0.56
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-low cDC - % of cDC: 61.837
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-high cDC - % of CD45+: 0.425
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of NK cells: 18.065
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Mature NK cells - % of NK cellls: 81.935
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Conventional DC (cDC) - % of DC: 91.517
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.078
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Immature NK cells - % of lymphocytes: 0.469
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
CD11b-low cDC - % of cDC: 63.096
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.113
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Mature NK cells - % of NK cellls: 80.46
16 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Mature NK cells - % of NK cellls: 80.237
15 weeks old
Pclaftm1a(EUCOMM)Wtsi homozygote
Resting Treg cells - % of CD45+: 0.644
The IMPC Newsletter
Get highlights of the most important data releases, news and events, delivered straight to your email inbox
Subscribe to newsletter