Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; LEFT EYE: Difficult to focus,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; LEFT EYE: Difficult to focus,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight debris and hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; LEFT EYE: Difficult to focus,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight debris and hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Abnormal pigmentation near optic disc,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Abnormal pigmentation near optic disc,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Abnormal pigmentation near optic disc,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Abnormal pigmentation near optic disc,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; LEFT EYE: Difficult to focus,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight debris and hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Abnormal pigmentation near optic disc,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Abnormal pigmentation near optic disc,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight debris and hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight debris and hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; LEFT EYE: Difficult to focus,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; RIGHT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and dysplasia ; RIGHT EYE: Very slight molten patches

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE: Crystallized debris, some dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Slight dysplasia

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia.; RIGHT EYE: Very large hyaloid present (some retinal obstruction) and some crystallized debris (difficult to image).

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Abnormal pigmentation near optic disc,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Abnormal pigmentation near optic disc,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; RIGHT EYE: Slight debris and hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and lens opacity ; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; LEFT EYE: Some lens opacity, some rd8,
Ophthalmoscope Observation: Both eyes slight dysplasia, slight hemorrhage; RIGHT EYE: Slight lens opacity, blood vessel early branching, slight rd8

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes moderate dysplasia and some rd8. Slight hemorrhaging and lens opacity (difficult to focus).; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity ; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some lens opacity (difficult to focus). Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Very small hyaloid present and slight lens opacity

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Abnormal pigmentation near optic disc,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Abnormal pigmentation near optic disc,
Ophthalmoscope Observation: Both eyes slight corneal opacity. Hyaloid and crystallized debris (obstruct part of retina, difficult to focus and image). Some lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; RIGHT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and lens opacity; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; LEFT EYE: Difficult to focus,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia ; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

15 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Multiple Hyaloids (large and small) present (obstructing the retina, connecting to multiple vessels), slight hemorrhage

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight dysplasia; RIGHT EYE: Slight hemorrhage

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, tiny hyaloid, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE:

14 weeks old

Dop1aem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; LEFT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris, some rd8, slight dysplasia, slight hemorrhage; RIGHT EYE: Large hyaloid present (obstructing the optic disc and retina), blood vessel slightly early branching

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