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Histopathology data for Thbs2

Home Genes Thbs2 Histopathology

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #4 Stomach [MA:0000353]
HOM F #2 Thymus [MA:0000142]
HOM F #1 Trachea [MA:0000441]
HOM F #1 Lymph node [MA:0000139] 1 0 Lymph node, mesenteric: Mild, paracortical lymphoid hyperplasia
HOM F #2 Small intestine [MA:0000337]
HOM F #1 Gall bladder [MA:0000356]
HOM F #2 Liver [MA:0000358] 1 0 Liver: Minimal, multifocal mixed inflammatory hepatitis
HOM M #3 Adrenal gland [MA:0000116]
HOM M #3 Seminal vesicle [MA:0000410]
HOM F #2 Tibia [MA:0001361]
HOM M #4 Sternum [MA:0001331]
HOM F #2 Mammary gland [MA:0000145]
HOM F #1 Nasal cavity [MA:0000284]
HOM M #4 Large intestine [MA:0000333]
HOM M #4 Tongue [MA:0000347]
HOM F #1 Eye [MA:0000261]
HOM F #1 Esophagus [MA:0000352]
HOM F #1 Bone marrow [MA:0000134]
HOM F #1 Sciatic nerve [MA:0001172]
HOM M #4 Lung [MA:0000415]
HOM M #3 Urinary bladder [MA:0000380]
HOM M #4 Adrenal gland [MA:0000116]
HOM M #4 Epididymis [MA:0000397]
HOM F #2 Spinal cord [MA:0000216]
HOM F #1 Bone [MA:0001459]
HOM M #3 Spleen [MA:0000141]
HOM F #1 Tooth [MA:0000348]
HOM M #4 Skin [MA:0000151]
HOM M #4 Seminal vesicle [MA:0000410]
HOM M #4 Urinary bladder [MA:0000380]
HOM M #4 Brain [MA:0000168]
HOM M #3 Stomach [MA:0000353]
HOM M #4 Esophagus [MA:0000352]
HOM F #1 Uterus [MA:0000389]
HOM M #3 Kidney [MA:0000368]
HOM F #1 Brain [MA:0000168]
HOM M #3 Lung [MA:0000415]
HOM M #4 Prostate gland [MA:0000404]
HOM F #2 Femur [MA:0001359]
HOM F #2 Pancreas [MA:0000120]
HOM F #1 Salivary gland [MA:0000346]
HOM M #3 Tongue [MA:0000347]
HOM F #2 Brown adipose tissue [MA:0000057]
HOM F #1 Knee joint [MA:0000471]
HOM M #4 Lymph node [MA:0000139] 2 0 Lymph node, mandibular, mesenteric: Mild to moderate, paracortical and follicular lymphoid hyperplasia
HOM M #3 Liver [MA:0000358]
HOM M #4 Spinal cord [MA:0000216]
HOM M #3 Ear [MA:0000236]
HOM M #3 Brain [MA:0000168]
HOM F #2 Adrenal gland [MA:0000116]
HOM M #3 Heart [MA:0000072]
HOM F #2 Salivary gland [MA:0000346]
HOM F #2 Ovary [MA:0000384]
HOM M #4 Femur [MA:0001359]
HOM M #4 Eye [MA:0000261]
HOM F #2 Bone [MA:0001459]
HOM F #1 Sternum [MA:0001331]
HOM M #3 Prostate gland [MA:0000404]
HOM F #1 Tongue [MA:0000347]
HOM M #4 Gall bladder [MA:0000356]
HOM F #2 Spleen [MA:0000141] 2 0 Spleen: Moderate, follicular lymphoid hyperplasia with mild increase in extramedullary hematopoiesis
HOM F #2 Trigeminal V ganglion [MA:0001080]
HOM M #4 Thyroid
HOM M #3 Small intestine [MA:0000337]
HOM F #1 Kidney [MA:0000368]
HOM F #1 Pancreas [MA:0000120]
HOM M #4 Skeletal muscle [MA:0003148]
HOM F #2 Urinary bladder [MA:0000380]
HOM M #3 Large intestine [MA:0000333]
HOM M #3 Sciatic nerve [MA:0001172]
HOM M #3 Testis [MA:0000411]
HOM F #1 Skeletal muscle [MA:0003148]
HOM F #2 Lymph node [MA:0000139] 2 0 Lymph node, mandibular, peripancreatic, mesenteric: Mild to moderate, follicular and paracortical lymphoid hyperplasia
HOM F #1 Skin [MA:0000151]
HOM M #4 Tibia [MA:0001361]
HOM F #1 Tibia [MA:0001361]
HOM M #4 Kidney [MA:0000368]
HOM F #1 Spleen [MA:0000141] 1 0 Spleen: Mild, follicular lymphoid hyperplasia
HOM M #3 Brown adipose tissue [MA:0000057]
HOM F #2 Kidney [MA:0000368]
HOM M #3 Esophagus [MA:0000352]
HOM F #1 Thyroid
HOM F #2 Tongue [MA:0000347]
HOM M #4 Spleen [MA:0000141]
HOM M #3 Bone marrow [MA:0000134]
HOM F #1 Trigeminal V ganglion [MA:0001080]
HOM F #2 Skin [MA:0000151]
HOM F #1 Spinal cord [MA:0000216]
HOM F #2 Uterus [MA:0000389]
HOM M #3 Bone [MA:0001459]
HOM M #4 Pancreas [MA:0000120]
HOM F #2 Heart [MA:0000072]
HOM M #3 Thyroid
HOM F #2 Brain [MA:0000168]
HOM F #2 Esophagus [MA:0000352]
HOM M #4 Trigeminal V ganglion [MA:0001080]
HOM M #3 Gall bladder [MA:0000356]
HOM M #3 Tooth [MA:0000348]
HOM F #2 Ear [MA:0000236]
HOM M #3 Salivary gland [MA:0000346]
HOM M #3 Trigeminal V ganglion [MA:0001080]
HOM M #3 Knee joint [MA:0000471]
HOM F #1 Femur [MA:0001359]
HOM F #1 Ovary [MA:0000384]
HOM M #4 Bone [MA:0001459]
HOM M #4 Salivary gland [MA:0000346]
HOM F #1 Urinary bladder [MA:0000380]
HOM M #3 Nasal cavity [MA:0000284]
HOM F #2 Eye [MA:0000261]
HOM M #4 Thymus [MA:0000142]
HOM F #2 Large intestine [MA:0000333]
HOM M #3 Lymph node [MA:0000139] 1 0 Lymph node, mesenteric: Mild, lymphoid hyperplasia
HOM F #1 Mammary gland [MA:0000145]
HOM F #1 Thymus [MA:0000142]
HOM M #4 Knee joint [MA:0000471]
HOM M #3 Trachea [MA:0000441]
HOM F #2 Thyroid
HOM F #2 Gall bladder [MA:0000356]
HOM M #4 Small intestine [MA:0000337]
HOM F #1 Adrenal gland [MA:0000116]
HOM F #2 Bone marrow [MA:0000134]
HOM F #2 Sternum [MA:0001331]
HOM M #4 Tooth [MA:0000348]
HOM F #2 Skeletal muscle [MA:0003148]
HOM F #1 Small intestine [MA:0000337]
HOM F #2 Sciatic nerve [MA:0001172]
HOM M #4 Testis [MA:0000411]
HOM M #3 Tibia [MA:0001361]
HOM M #4 Trachea [MA:0000441]
HOM M #4 Sciatic nerve [MA:0001172]
HOM F #2 Knee joint [MA:0000471]
HOM F #1 Lung [MA:0000415]
HOM F #1 Stomach [MA:0000353] 2 0 Stomach, glandular: Moderate, regionally extensive, pyogranulomatous gastritis with intralesional hair shaft
HOM M #3 Thymus [MA:0000142]
HOM F #1 Heart [MA:0000072]
HOM M #4 Bone marrow [MA:0000134]
HOM F #1 Liver [MA:0000358]
HOM M #4 Brown adipose tissue [MA:0000057]
HOM F #2 Tooth [MA:0000348]
HOM M #4 Nasal cavity [MA:0000284]
HOM F #2 Stomach [MA:0000353]
HOM F #2 Nasal cavity [MA:0000284]
HOM F #1 Brown adipose tissue [MA:0000057]
HOM M #4 Heart [MA:0000072]
HOM M #4 Liver [MA:0000358] 1 0 Liver: Minimal, focal hepatitis
HOM F #2 Trachea [MA:0000441]
HOM M #4 Ear [MA:0000236]
HOM M #3 Femur [MA:0001359]
HOM M #3 Pancreas [MA:0000120]
HOM F #1 Ear [MA:0000236]
HOM M #3 Skeletal muscle [MA:0003148]
HOM F #2 Lung [MA:0000415]
HOM M #3 Epididymis [MA:0000397]
HOM M #3 Spinal cord [MA:0000216]
HOM M #3 Skin [MA:0000151]
HOM M #3 Sternum [MA:0001331]
HOM F #1 Large intestine [MA:0000333]
HOM M #3 Eye [MA:0000261]

Associated histopathology images

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