Histopathology data for Ralb

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #3 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM F #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #1 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM M #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #2 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM M #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #2 Eye with optic nerve developmental dysplasia [MPATH:64] 1 0 multi-localised Retinal dysplasia
HOM F #3 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM F #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #3 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #3 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM F #2 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #4 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM M #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #4 Testes normal [MPATH:458] 0 0
HOM M #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #3 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #1 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #4 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #2 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM F #2 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #4 Thyroid normal [MPATH:458] 0 0
HOM F #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #2 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #3 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #1 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #4 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #2 Lymph node [MA:0000139] hyperplasia [MPATH:134] 2 0 distributed Lymphoid hyperplasia
HOM M #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #4 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #1 Prostate normal [MPATH:458] 0 0
HOM F #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #4 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #4 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM F #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #4 Prostate normal [MPATH:458] 0 0
HOM F #3 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #4 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM F #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #1 Testes normal [MPATH:458] 0 0
HOM F #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #4 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM F #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #4 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM M #4 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #1 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #1 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM F #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #2 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #1 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM M #1 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #3 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM F #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #3 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #1 Brain [MA:0000168] process of degenerative change [MPATH:14] 3 0 hydrocephalus MPATH:639 distributed Dilation of the brain ventricles
HOM F #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #4 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #4 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM M #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #2 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM F #3 Thyroid normal [MPATH:458] 0 0
HOM F #3 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #2 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #3 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM M #1 Thyroid normal [MPATH:458] 0 0
HOM M #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #1 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM F #2 Thyroid normal [MPATH:458] 0 0
HOM M #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #2 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM F #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #4 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM F #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #1 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #1 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #3 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #4 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM F #2 Spleen [MA:0000141] normal [MPATH:458] 0 0

Associated histopathology images

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