Histopathology data for Plbd1

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #3 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM F #2 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #1 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM F #1 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #1 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #1 Liver [MA:0000358] lipid deposition [MPATH:42] 2 0 multi-localised Hepatic lipidosis.
HOM F #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #3 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM F #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #3 Testes normal [MPATH:458] 0 0
HOM M #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #3 Thyroid normal [MPATH:458] 0 0
HOM F #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #2 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #3 Lymph node [MA:0000139] neoplasm [MPATH:218] Not applicable 0 multi-localised Lymphoma
HOM M #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #2 Liver [MA:0000358] lipid deposition [MPATH:42] 2 0 multi-localised Hepatic lipidosis.
HOM F #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #2 Stomach [MA:0000353] inflammation [MPATH:212] 2 0 subacute multi-localised Gastritis, suppurative
HOM F #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #3 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #1 Thyroid normal [MPATH:458] 0 0
HOM M #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #2 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM F #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #2 Adrenal gland [MA:0000116] process of degenerative change [MPATH:14] 1 0 distributed Vacuolar degeneration of X-zone of the adenal gland with cytoplasmic ceroid accumulation (X-zone involution).
HOM M #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #2 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM F #1 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM F #1 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM F #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #2 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM F #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #1 Stomach [MA:0000353] inflammation [MPATH:212] 1 0 subacute multi-localised Gastritis, suppurative
HOM M #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #3 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #3 Liver [MA:0000358] lipid deposition [MPATH:42] 3 0 distributed Hepatic lipisosis
HOM F #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #2 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM M #3 Prostate normal [MPATH:458] 0 0
HOM F #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #1 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #3 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM F #1 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM F #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #3 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM F #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #2 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #2 Thyroid normal [MPATH:458] 0 0
HOM M #3 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM F #2 Lymph node [MA:0000139] hyperplasia [MPATH:134] 1 0 subacute distributed Lymphoid hyperplasia.
HOM M #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #2 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM F #2 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #3 Stomach [MA:0000353] inflammation [MPATH:212] 2 0 subacute multi-localised Gastritis, suppurative
HOM F #1 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM M #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #3 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #3 Brain [MA:0000168] process of degenerative change [MPATH:14] 1 0 hydrocephalus MPATH:639 hydrocephalus, lateral ventricle
HOM F #1 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM F #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0

Associated histopathology images

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