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Histopathology data for Pdlim7

Home Genes Pdlim7 Histopathology

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #2 Small intestine [MA:0000337]
HOM M #4 Bone marrow [MA:0000134]
HOM M #1 Spinal cord [MA:0000216]
HOM F #2 Brain [MA:0000168]
HOM F #2 Uterus [MA:0000389]
HOM F #3 Spleen [MA:0000141]
HOM M #4 Spleen [MA:0000141] 1 0 Spleen: Extramedullary hematopoiesis, mild increase
HOM M #4 Trachea [MA:0000441]
HOM M #4 Kidney [MA:0000368]
HOM F #2 Mammary gland [MA:0000145]
HOM M #1 Heart [MA:0000072]
HOM F #2 Femur [MA:0001359]
HOM M #4 Skeletal muscle [MA:0003148]
HOM F #3 Thyroid
HOM M #1 Trigeminal V ganglion [MA:0001080]
HOM F #2 Tibia [MA:0001361]
HOM M #1 Nasal cavity [MA:0000284]
HOM F #3 Gall bladder [MA:0000356]
HOM M #1 Esophagus [MA:0000352]
HOM F #2 Salivary gland [MA:0000346]
HOM M #4 Prostate gland [MA:0000404]
HOM F #3 Tongue [MA:0000347]
HOM F #3 Lung [MA:0000415]
HOM M #4 Gall bladder [MA:0000356]
HOM F #3 Skeletal muscle [MA:0003148]
HOM F #3 Lymph node [MA:0000139]
HOM M #1 Urinary bladder [MA:0000380]
HOM M #1 Eye [MA:0000261] 1 0 Eye, unilateral: Mild, multifocal retinal dysplasia
HOM M #1 Large intestine [MA:0000333]
HOM M #4 Sciatic nerve [MA:0001172]
HOM M #4 Thymus [MA:0000142]
HOM M #4 Testis [MA:0000411] 2 1 Testes, bilateral: Increased multinucleated giant cells, moderate increase with multifocal atypical residual bodies, apoptotic bodies, and rare, late pachytene mitoses
HOM F #3 Sciatic nerve [MA:0001172]
HOM M #4 Knee joint [MA:0000471]
HOM M #4 Lymph node [MA:0000139] 1 0 Lymph node, mesenteric: Mild, paracortical lymphoid hyperplasia
HOM F #2 Bone [MA:0001459]
HOM F #3 Bone marrow [MA:0000134]
HOM M #4 Lung [MA:0000415]
HOM M #1 Liver [MA:0000358]
HOM M #4 Tongue [MA:0000347]
HOM F #3 Kidney [MA:0000368]
HOM F #3 Knee joint [MA:0000471]
HOM F #3 Trachea [MA:0000441]
HOM F #3 Nasal cavity [MA:0000284]
HOM F #2 Skeletal muscle [MA:0003148]
HOM F #2 Trachea [MA:0000441]
HOM M #1 Femur [MA:0001359]
HOM F #3 Bone [MA:0001459]
HOM M #1 Testis [MA:0000411] 2 1 Testes, bilateral: Increased multinucleated giant cells, moderate increase with multifocal atypical residual bodies, apoptotic bodies, and rare, late pachytene mitoses
HOM F #2 Urinary bladder [MA:0000380]
HOM M #1 Gall bladder [MA:0000356]
HOM M #4 Large intestine [MA:0000333]
HOM F #3 Eye [MA:0000261]
HOM F #2 Knee joint [MA:0000471]
HOM M #4 Brain [MA:0000168]
HOM F #2 Spleen [MA:0000141] 1 0 Spleen: Extramedullary hematopoiesis, mild increase
HOM F #2 Kidney [MA:0000368]
HOM M #1 Salivary gland [MA:0000346]
HOM F #2 Spinal cord [MA:0000216]
HOM F #2 Lymph node [MA:0000139] 1 0 Lymph node, mesenteric: Mild, paracortical and follicular lymphoid hyperplasia
HOM F #2 Ear [MA:0000236]
HOM M #4 Small intestine [MA:0000337]
HOM M #1 Tooth [MA:0000348]
HOM M #4 Femur [MA:0001359]
HOM M #1 Bone marrow [MA:0000134]
HOM M #1 Epididymis [MA:0000397] 1 0 Epididymis: Increased luminal cell debris, mild
HOM F #3 Trigeminal V ganglion [MA:0001080]
HOM F #2 Liver [MA:0000358] 1 0 Liver: Mild, focal, neutrophilic and mononuclear, hepatitis
HOM M #4 Ear [MA:0000236]
HOM M #1 Stomach [MA:0000353]
HOM F #3 Sternum [MA:0001331]
HOM F #2 Skin [MA:0000151]
HOM M #1 Brown adipose tissue [MA:0000057]
HOM F #3 Esophagus [MA:0000352]
HOM F #3 Tibia [MA:0001361]
HOM F #3 Heart [MA:0000072]
HOM F #2 Pancreas [MA:0000120]
HOM F #2 Thymus [MA:0000142]
HOM M #1 Sciatic nerve [MA:0001172]
HOM M #4 Salivary gland [MA:0000346]
HOM F #2 Ovary [MA:0000384]
HOM F #3 Adrenal gland [MA:0000116]
HOM F #2 Tongue [MA:0000347]
HOM F #2 Lung [MA:0000415]
HOM M #1 Thymus [MA:0000142]
HOM F #3 Salivary gland [MA:0000346]
HOM F #3 Brown adipose tissue [MA:0000057]
HOM M #1 Ear [MA:0000236]
HOM M #4 Pancreas [MA:0000120]
HOM F #3 Tooth [MA:0000348]
HOM M #1 Knee joint [MA:0000471]
HOM M #1 Skeletal muscle [MA:0003148]
HOM F #3 Urinary bladder [MA:0000380]
HOM F #3 Liver [MA:0000358]
HOM F #3 Pancreas [MA:0000120]
HOM M #4 Liver [MA:0000358]
HOM F #2 Sciatic nerve [MA:0001172]
HOM F #3 Skin [MA:0000151]
HOM F #3 Brain [MA:0000168]
HOM M #4 Urinary bladder [MA:0000380]
HOM F #2 Large intestine [MA:0000333]
HOM F #2 Adrenal gland [MA:0000116]
HOM F #2 Nasal cavity [MA:0000284]
HOM M #1 Sternum [MA:0001331]
HOM M #4 Tooth [MA:0000348]
HOM M #1 Tibia [MA:0001361]
HOM M #4 Skin [MA:0000151]
HOM M #4 Spinal cord [MA:0000216]
HOM M #1 Brain [MA:0000168]
HOM M #4 Brown adipose tissue [MA:0000057]
HOM F #2 Sternum [MA:0001331]
HOM M #1 Spleen [MA:0000141]
HOM F #3 Spinal cord [MA:0000216]
HOM F #2 Thyroid
HOM M #1 Small intestine [MA:0000337]
HOM M #4 Stomach [MA:0000353]
HOM M #4 Epididymis [MA:0000397] 1 0 Epididymis: Increased luminal cell debris, mild
HOM F #3 Stomach [MA:0000353]
HOM M #4 Eye [MA:0000261] 1 0 Eye, unilateral: Minimal, multifocal, retinal dysplasia
HOM F #2 Stomach [MA:0000353]
HOM F #3 Ear [MA:0000236]
HOM F #2 Esophagus [MA:0000352]
HOM M #4 Seminal vesicle [MA:0000410]
HOM M #1 Adrenal gland [MA:0000116]
HOM M #4 Tibia [MA:0001361]
HOM F #2 Heart [MA:0000072]
HOM F #3 Thymus [MA:0000142]
HOM M #1 Skin [MA:0000151] 1 0 Haired skin: Mild, focal, mononuclear dermatitis with mild acanthosis, orthokeratotic hyperkeratosis and focal serocellular crust
HOM M #1 Thyroid
HOM F #2 Trigeminal V ganglion [MA:0001080]
HOM F #3 Ovary [MA:0000384]
HOM F #3 Mammary gland [MA:0000145]
HOM M #1 Pancreas [MA:0000120]
HOM M #4 Bone [MA:0001459]
HOM F #3 Small intestine [MA:0000337]
HOM F #2 Brown adipose tissue [MA:0000057]
HOM M #4 Thyroid
HOM M #1 Lung [MA:0000415]
HOM M #1 Trachea [MA:0000441]
HOM M #1 Seminal vesicle [MA:0000410]
HOM F #3 Uterus [MA:0000389] 1 0 Uterus: Mild stromal edema
HOM M #1 Tongue [MA:0000347]
HOM M #4 Nasal cavity [MA:0000284]
HOM M #4 Adrenal gland [MA:0000116]
HOM M #1 Bone [MA:0001459]
HOM F #2 Bone marrow [MA:0000134]
HOM M #4 Heart [MA:0000072]
HOM F #3 Femur [MA:0001359]
HOM F #3 Large intestine [MA:0000333]
HOM M #1 Kidney [MA:0000368]
HOM M #1 Lymph node [MA:0000139] 1 0 Lymph node, mesenteric: Mild, paracortical lymphoid hyperplasia
HOM F #2 Gall bladder [MA:0000356]
HOM F #2 Tooth [MA:0000348]
HOM M #4 Trigeminal V ganglion [MA:0001080]
HOM M #4 Esophagus [MA:0000352]
HOM M #1 Prostate gland [MA:0000404]
HOM F #2 Eye [MA:0000261]
HOM M #4 Sternum [MA:0001331]

Associated histopathology images

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