Histopathology data for Carmil1

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #3 Bone marrow [MA:0000134] metaplasia [MPATH:160] 1 0 multi-localised lymphoid metaplasia
HOM M #2 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM F #1 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM F #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #2 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #1 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM F #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #2 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #3 Brain [MA:0000168] process of degenerative change [MPATH:14] 1 0 hydrocephalus MPATH:639 hydrocephalus, third ventricle
HOM M #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #3 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #3 Testes normal [MPATH:458] 0 0
HOM M #2 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #3 Thyroid normal [MPATH:458] 0 0
HOM M #3 Lymph node [MA:0000139] hyperplasia [MPATH:134] 2 0 subacute distributed Lymphoid hyperplasia.
HOM F #1 Tibia [MA:0001361] normal [MPATH:458] 0 0
HOM M #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #2 Thymus [MA:0000142] developmental and structural abnormality [MPATH:55] 1 0 localized Focal epithelial inclusion cyst
HOM M #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #2 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #2 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM M #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #1 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM M #2 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #2 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM F #1 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM M #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #1 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM F #1 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #2 Liver [MA:0000358] lipid deposition [MPATH:42] 2 0 multi-localised Hepatic lipidosis.
HOM F #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #3 Sternum [MA:0001331] normal [MPATH:458] 0 0
HOM M #3 Brown adipose tissue [MA:0000057] normal [MPATH:458] 0 0
HOM F #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #3 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM M #3 Prostate normal [MPATH:458] 0 0
HOM F #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #1 Liver [MA:0000358] lipid deposition [MPATH:42] 2 0 multi-localised Hepatic lipidosis.
HOM M #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #3 Liver [MA:0000358] lipid deposition [MPATH:42] 2 0 distributed Hepatic lipidosis
HOM M #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #1 Thyroid normal [MPATH:458] 0 0
HOM M #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #3 Knee joint [MA:0000471] normal [MPATH:458] 0 0
HOM M #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #2 Testes normal [MPATH:458] 0 0
HOM F #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #3 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM M #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #2 Brown adipose tissue [MA:0000057] inflammation [MPATH:212] 1 0 localized Mild lymphocytic steatitis
HOM F #1 Trigeminal V nerve [MA:0001100] normal [MPATH:458] 0 0
HOM M #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM F #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #2 Thyroid normal [MPATH:458] 0 0
HOM F #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #2 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #3 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #3 Stomach [MA:0000353] inflammation [MPATH:212] 1 0 multi-localised subacute Gastritis, suppurative
HOM M #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM F #1 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #2 Prostate normal [MPATH:458] 0 0
HOM F #1 Stomach [MA:0000353] inflammation [MPATH:212] 2 0 multi-localised subacute Gastritis, suppurative
HOM M #3 Epididymis [MA:0000397] normal [MPATH:458] 0 0

Associated histopathology images

Carmil1
homozygote
Carmil1tm1a(KOMP)Wtsi
experimental
Carmil1
homozygote
Carmil1tm1a(KOMP)Wtsi
experimental
Carmil1
homozygote
Carmil1tm1a(KOMP)Wtsi
experimental
Carmil1
homozygote
Carmil1tm1a(KOMP)Wtsi
experimental
Carmil1
homozygote
Carmil1tm1a(KOMP)Wtsi
experimental
Carmil1
homozygote
Carmil1tm1a(KOMP)Wtsi
experimental

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