Histopathology data for Aplp2

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #3 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM F #4 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #3 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM M #1 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM M #2 Seminal vesicle [MA:0000410] normal [MPATH:458] 0 0
HOM F #3 Prostate Not applicable
HOM F #4 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #4 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #1 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM M #2 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #2 Prostate normal [MPATH:458] 0 0
HOM F #4 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #3 Seminal vesicle [MA:0000410] Not applicable
HOM F #4 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #1 Prostate normal [MPATH:458] 0 0
HOM M #1 Ovary [MA:0000384] Not applicable
HOM F #4 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #3 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM M #1 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #2 Uterus [MA:0000389] Not applicable
HOM M #1 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #2 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #3 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #4 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #1 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #3 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM M #1 Uterus [MA:0000389] Not applicable
HOM F #3 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM F #4 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #3 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #3 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #2 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM M #1 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #1 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #2 Femur [MA:0001359] normal [MPATH:458] 0 0
HOM F #4 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM M #1 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM M #1 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM F #3 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM M #2 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM F #4 Ovary [MA:0000384] normal [MPATH:458] 0 0
HOM M #2 Ovary [MA:0000384] Not applicable
HOM M #1 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM F #3 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM M #2 Eye with optic nerve normal [MPATH:458] 0 0
HOM F #4 Uterus [MA:0000389] normal [MPATH:458] 0 0
HOM F #3 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM M #2 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM F #3 Salivary gland [MA:0000346] normal [MPATH:458] 0 0
HOM M #1 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #3 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #1 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #1 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #3 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #1 Thyroid normal [MPATH:458] 0 0
HOM F #4 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #2 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM M #2 Gall bladder [MA:0000356] normal [MPATH:458] 0 0
HOM F #4 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #2 Mammary gland [MA:0000145] Not applicable
HOM F #4 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #2 Skin [MA:0000151] normal [MPATH:458] 0 0
HOM F #3 Sciatic nerve [MA:0001172] normal [MPATH:458] 0 0
HOM M #2 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #4 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM F #3 Mammary gland [MA:0000145] normal [MPATH:458] 0 0
HOM F #3 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #2 Urinary bladder [MA:0000380] normal [MPATH:458] 0 0
HOM F #4 Liver [MA:0000358] normal [MPATH:458] 0 0
HOM F #4 Seminal vesicle [MA:0000410] Not applicable
HOM M #1 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #4 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #2 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #1 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #4 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #1 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM F #3 Epididymis [MA:0000397] Not applicable
HOM F #3 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #4 Epididymis [MA:0000397] Not applicable
HOM F #4 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #3 Testes Not applicable
HOM F #4 Testes Not applicable
HOM F #3 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #4 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM M #2 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM F #3 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #1 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #2 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #3 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #3 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #2 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #4 Bone marrow [MA:0000134] normal [MPATH:458] 0 0
HOM M #1 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #4 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM M #1 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM M #2 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #2 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM M #2 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #1 Testes normal [MPATH:458] 0 0
HOM M #1 Small intestine [MA:0000337] normal [MPATH:458] 0 0
HOM F #3 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #3 Trachea [MA:0000441] normal [MPATH:458] 0 0
HOM F #3 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #2 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM M #2 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #4 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM M #1 Mammary gland [MA:0000145] Not applicable
HOM M #2 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #2 Thyroid normal [MPATH:458] 0 0
HOM F #4 Large intestine [MA:0000333] normal [MPATH:458] 0 0
HOM M #2 Brain [MA:0000168] normal [MPATH:458] 0 0
HOM F #4 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #3 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM F #3 Thyroid normal [MPATH:458] 0 0
HOM M #2 Kidney [MA:0000368] normal [MPATH:458] 0 0
HOM F #4 Skeletal muscle [MA:0003148] normal [MPATH:458] 0 0
HOM M #1 Stomach [MA:0000353] normal [MPATH:458] 0 0
HOM F #4 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM M #2 Heart [MA:0000072] normal [MPATH:458] 0 0
HOM M #1 Thymus [MA:0000142] normal [MPATH:458] 0 0
HOM M #1 Eye with optic nerve normal [MPATH:458] 0 0
HOM M #1 Epididymis [MA:0000397] normal [MPATH:458] 0 0
HOM M #2 Esophagus [MA:0000352] normal [MPATH:458] 0 0
HOM F #3 Lymph node [MA:0000139] normal [MPATH:458] 0 0
HOM F #3 Spleen [MA:0000141] normal [MPATH:458] 0 0
HOM F #4 Prostate Not applicable
HOM M #1 Spinal cord [MA:0000216] normal [MPATH:458] 0 0
HOM F #4 Thyroid normal [MPATH:458] 0 0
HOM F #4 Pancreas [MA:0000120] normal [MPATH:458] 0 0
HOM M #1 Lung [MA:0000415] normal [MPATH:458] 0 0
HOM M #1 Adrenal gland [MA:0000116] normal [MPATH:458] 0 0
HOM M #2 Testes normal [MPATH:458] 0 0

Associated histopathology images

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