Gene: Abca1

Name ATP-binding cassette, sub-family A (ABC1), member 1

Synonyms ABC1

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:99607   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Lethal

Phenotype associations for Abca1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Abca1 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Abca1tm1b(EUCOMM)Hmgu HET Male embryonic day 18.5 0.0
abnormal embryo size Abca1tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 18.5 0.0
preweaning lethality, complete penetrance Abca1tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
increased or absent threshold for auditory brainstem response Abca1tm1b(EUCOMM)Hmgu HET Female Male postnatal 8.15E-9

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No (5/393) (2/3)
Aorta 3 No (1/562) (3/3)
Bone 3 No (1/539) (3/3)
Brain 3 No (6/562) (3/3)
Brainstem 3 No (4/562) (3/3)
Brown adipose tissue 3 No (3/3)
Cartilage tissue 3 No (1/562) (3/3)
Cecum 3 No (1/355)
Cerebellum 3 No (4/562) (3/3)
Cerebral cortex 3 No (5/562) (3/3)
Esophagus 3 No (2/393)
Eye 3 No (1/562)
Gall bladder 3 No (3/3)
Heart 3 No (3/562) (3/3)
Hippocampus 3 No (5/562) (3/3)
Hypothalamus 3 No (4/562) (3/3)
Kidney 3 No (20/562) (3/3)
Large intestine 3 No (12/562)
Liver 3 No (3/3)
Lower urinary tract 3 No (3/562) (3/3)
Lung 3 No (3/562) (3/3)
Lymph node 3 No (1/562) (3/3)
Mammary gland 3 No
Olfactory lobe 3 No (4/393) (3/3)
Oral epithelium 3 No (3/3)
Ovary 3 No (1/562) (1/3)
Oviduct 3 No (2/562) (1/3)
Pancreas 3 No (6/562) (3/3)
Parathyroid gland 3 No (2/540)
Peripheral nervous system 3 No (3/562) (3/3)
Peyer's patch 3 No (1/393)
Pituitary gland 3 No (1/562) (3/3)
Prostate gland 3 No (5/562) (2/3)
Skeletal muscle 3 No (3/3)
Skin 3 No (1/562) (3/3)
Small intestine 3 No (11/562)
Spinal cord 3 No (3/562) (3/3)
Spleen 3 No (4/562)
Stomach 3 No (9/562) (3/3)
Striatum 3 No (4/562) (3/3)
Testis 3 No (4/562) (2/3)
Thymus 3 No
Thyroid gland 3 No (16/562) (3/3)
Trachea 3 No (3/562) (3/3)
Trigeminal V nerve 3 No (3/3)
Uterus 3 No (2/562) (1/3)
Vas deferens 3 No (1/360) (1/3)
Vascular system 3 No (1/393)
White adipose tissue 3 No (3/3)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system
    endocrine system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2 (1/3)
Axial skeleton 2 (1/5)
Brain 2 (6/440) (2/4)
Central nervous system ganglion 2 (1/5) (1/4)
Cranium 2 Image Only
Dorsal root ganglion 2 (1/3)
Ear 2 (1/440)
Embryo 2 (1/440) (2/4)
Outer ear 2
Eye 2 (1/440)
Femur pre-cartilage condensation 2 Image Only (2/4)
Foot 2 (2/4)
Forearm 2
Forebrain 2 (1/440) (2/4)
Forelimb 2 (1/440) (2/4)
Fronto-nasal process 2 (1/4) (2/4)
Gut 2 (1/4)
Hand 2 (2/4)
Head 2 (5/440) (2/4)
Head mesenchyme 2 (1/3) (2/4)
Heart 2 (1/440)
Heart ventricle 2 (1/3)
Hindbrain 2 (5/440) (2/4)
Hindlimb 2 (1/440) (2/4)
Humerus pre-cartilage condensation 2 Image Only
Inner ear 2 Image Only
Intestine 2
Liver 2 (1/440) (2/4)
Lower leg 2
Lung 2 (1/440)
Mandibular process 2 (1/440) (2/4)
Maxillary process 2 (1/440)
Mesonephros of female 2 Image Only
Mesonephros of male 2 Image Only
Metanephros 2 Image Only
Midbrain 2 (1/440) (2/4)
Nasal septum 2
Nose 2 (1/5)
Notochord 2
Oral cavity 2 (1/440) (2/4)
Outflow tract 2 (1/3)
Pancreas 2 Image Only
Pericardium 2 (1/2) (2/4)
Pharynx 2 Image Only
Radius-ulna pre-cartilage condensation 2 Image Only (2/4)
Rib pre-cartilage condensation 2 (1/2) (2/4)
Skeleton 2 (1/5)
Skin 2 (1/440)
Spinal cord 2 (1/4) (2/4)
Stomach 2 Image Only (2/4)
Tail 2 (1/440) (2/4)
Tail somite 2 (1/440) (2/4)
Thoracic vertebral cartilage condensation 2 (1/2) (2/4)
Tongue 2 Image Only (2/4)
Trachea 2 Image Only
Trunk mesenchyme 2 (1/3) (2/4)
Umbilical artery embryonic part 2
Umbilical vein embryonic part 2
Upper arm 2
Upper leg 2
Urinary system 2 Image Only
Vibrissa 2


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • X-ray: XRay Images Skull Lateral Orientation
    9 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • X-ray: XRay Images Forepaw
    9 Images
  • Adult LacZ: LacZ Images Wholemount
    35 Images
  • Embryo LacZ: LacZ images wholemount
    7 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Abca1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Abca1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Abca1tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Abca1tm398(L1L2_Bact_P)
Vector
Gene
Abca1tm398(L1L2_gt0)
Vector
Gene
Abca1tm398(L1L2_st0)
Vector
Gene