Gene: Dhx40

Order

Name DEAH (Asp-Glu-Ala-His) box polypeptide 40

Synonyms
  • ARG147
  • DDX40
  • 2410016C14Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1914737    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Dhx40

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Dhx40 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased bone mineral density Dhx40tm1(NCOM)Cmhd HOM Male postnatal 2.9E-6
abnormal bone structure Dhx40tm1(NCOM)Cmhd HOM Male postnatal 6.13E-6
abnormal bone mineralization Dhx40tm1(NCOM)Cmhd HOM Male postnatal 7.8E-6
abnormal behavior Dhx40tm1(NCOM)Cmhd HOM Female postnatal 1.51E-5
abnormal retinal vasculature morphology Dhx40tm1b(KOMP)Wtsi HOM Female Male postnatal 1.66E-5
abnormal cornea morphology Dhx40tm1b(KOMP)Wtsi HOM Male postnatal 6.58E-5
decreased circulating cholesterol level Dhx40tm1(NCOM)Cmhd HOM Female Male postnatal 9.29E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Bone 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cecum 2 No (12/383)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No (2/2)
Oral epithelium 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (1/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No (2/2)
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No (2/2)
Trigeminal V nerve 2 No (2/2)
Uterus 2 No (1/2)
Vas deferens 2 No (15/388)
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    respiratory system
    digestive system
    cardiovascular system
    nervous system
    set of connective tissues
    reproductive system
    musculoskeletal system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Wholemount
    13 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Dhx40tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Dhx40tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Dhx40tm1(NCOM)Cmhd Reporter-tagged deletion allele (with selection cassette)
Vector
Gene