Gene: Ampd1

Name adenosine monophosphate deaminase 1

Synonyms Ampd-1

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:88015   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Subviable

Phenotype associations for Ampd1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ampd1 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
enlarged lymph nodes Ampd1tm1b(KOMP)Wtsi HOM Female postnatal 0.0
preweaning lethality, incomplete penetrance Ampd1tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
increased mean platelet volume Ampd1tm1b(KOMP)Wtsi HET Female postnatal 1.0E-6
decreased neutrophil cell number Ampd1tm1b(KOMP)Wtsi HET Female Male postnatal 2.05E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (1/2)
Large intestine 2 No (12/562) (1/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Olfactory lobe 2 No (4/393)
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562) (1/2)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562) (1/2)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562)
Thymus 2 No
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    digestive system reproductive system exocrine system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    18 Images
  • X-ray: XRay Images Hind Leg and Hip
    18 Images
  • X-ray: XRay Images Dorso Ventral
    18 Images
  • X-ray: XRay Images Lateral Orientation
    36 Images
  • Gross Pathology and Tissue Collection
    12 Images
  • Eye Morphology: Images Ophthalmoscopy
    14 Images
  • Adult LacZ: LacZ Images Section
    4 Images
  • Eye Morphology: Images Slit Lamp
    7 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ampd1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ampd1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene