Gene: Acap1

Name ArfGAP with coiled-coil, ankyrin repeat and PH domains 1

Synonyms Centb1

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:2388270   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Acap1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Acap1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased circulating glucose level Acap1tm1.1(KOMP)Vlcg HOM Female Male postnatal 1.33E-6
decreased circulating iron level Acap1tm1.1(KOMP)Vlcg HOM Female postnatal 3.35E-5
decreased leukocyte cell number Acap1tm1.1(KOMP)Vlcg HOM Female Male postnatal 6.77E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562)
Bone 2 No (1/539) (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393) (2/2)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system set of connective tissues reproductive system adipose tissue musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/440)
Dorsal root ganglion 2 (1/3)
Ear 2 (1/440)
Embryo 2 (1/440)
Eye 2 (1/440)
Foot 2
Forebrain 2 (1/440)
Forelimb 2 (1/440)
Fronto-nasal process 2 (1/4)
Hand 2
Head 2 (5/440)
Heart 2 (1/440)
Hindbrain 2 (5/440)
Hindlimb 2 (1/440)
Liver 2 (1/440)
Lung 2 (1/440)
Mandibular process 2 (1/440)
Maxillary process 2 (1/440)
Midbrain 2 (1/440)
Nose 2 (1/5)
Oral cavity 2 (1/440)
Skin 2 (1/440)
Spinal cord 2 (1/4)
Tail 2 (1/440)
Tail somite 2 (1/440)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • X-ray: XRay Images Skull Lateral Orientation
    9 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images
  • X-ray: XRay Images Forepaw
    9 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • Sleep Wake: Wake state (bmp file)
    12 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Acap1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Acap1tm40074(L1L2_gt1)
Vector
Gene
Acap1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene