Gene: Tox


Name thymocyte selection-associated high mobility group box

Synonyms 1700007F02Rik

Status ES CellsMice
phenotype data available

Links MGI:2181659    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Tox

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Tox data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased prepulse inhibition Toxtm1b(KOMP)Wtsi HOM Female Male postnatal 3.66E-15
absent startle reflex Toxtm1b(KOMP)Wtsi HOM Female Male postnatal 5.56E-13
decreased startle reflex Toxtm1b(KOMP)Wtsi HOM Female Male postnatal 5.38E-11
decreased bone mineral density Toxtm1b(KOMP)Wtsi HOM Female postnatal 6.33E-9
decreased bone mineral content Toxtm1b(KOMP)Wtsi HOM Female postnatal 1.28E-7
increased or absent threshold for auditory brainstem response Toxtm1b(KOMP)Wtsi HOM Female Male postnatal 1.2E-6
decreased lean body mass Toxtm1b(KOMP)Wtsi HOM Female postnatal 1.4E-6
decreased vertical activity Toxtm1b(KOMP)Wtsi HOM Male postnatal 2.95E-6

Download data as: TSV XLS


Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Toxtm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Toxtm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)