Phenotype Allele Zygosity Sex Life Stage Procedure Parameter Phenotyping Center Source P Value Data abnormal heart morphology Tox homozygote female Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2181659/IMPC_PAT_006_002 enlarged heart Tox homozygote female Early adult Gross Pathology and Tissue Collection Heart UC Davis IMPC 0.0 //www.mousephenotype.org/data/grosspath/MGI:2181659/IMPC_PAT_006_002 abnormal startle reflex Tox homozygote male Early adult Combined SHIRPA and Dysmorphology Startle response UC Davis IMPC 5.73E-13 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_CSD_036_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_036_001&phenotyping_center=UC Davis decreased prepulse inhibition Tox homozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI3 UC Davis IMPC 2.1E-12 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_ACS_035_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_035_001&phenotyping_center=UC Davis decreased bone mineral density Tox homozygote female Early adult Body Composition (DEXA lean/fat) Bone Mineral Density (excluding skull) UC Davis IMPC 1.51E-11 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_DXA_004_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_004_001&phenotyping_center=UC Davis increased spleen weight Tox homozygote male Early adult Organ Weight Spleen weight UC Davis IMPC 6.59E-11 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=UCD_OWT_003_001&pipeline_stable_id=UCD_001&procedure_stable_id=UCD_OWT_001¶meter_stable_id=UCD_OWT_003_001&phenotyping_center=UC Davis decreased prepulse inhibition Tox homozygote male Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 UC Davis IMPC 8.23E-9 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_ACS_034_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_034_001&phenotyping_center=UC Davis decreased prepulse inhibition Tox homozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - Global UC Davis IMPC 3.83E-8 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_ACS_037_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_037_001&phenotyping_center=UC Davis decreased bone mineral content Tox homozygote female Early adult Body Composition (DEXA lean/fat) Bone Mineral Content (excluding skull) UC Davis IMPC 8.98E-8 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_DXA_005_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_DXA_001¶meter_stable_id=IMPC_DXA_005_001&phenotyping_center=UC Davis decreased prepulse inhibition Tox homozygote male Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - Global UC Davis IMPC 6.69E-7 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_ACS_037_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_037_001&phenotyping_center=UC Davis decreased prepulse inhibition Tox homozygote female Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI2 UC Davis IMPC 1.59E-6 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_ACS_034_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_034_001&phenotyping_center=UC Davis decreased prepulse inhibition Tox homozygote male Early adult Acoustic Startle and Pre-pulse Inhibition (PPI) % Pre-pulse inhibition - PPI3 UC Davis IMPC 9.85E-6 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_ACS_035_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ACS_003¶meter_stable_id=IMPC_ACS_035_001&phenotyping_center=UC Davis decreased circulating cholesterol level Tox homozygote male Early adult Clinical Chemistry Total cholesterol UC Davis IMPC 1.4E-5 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_CBC_015_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_015_001&phenotyping_center=UC Davis increased circulating alkaline phosphatase level Tox homozygote female Early adult Clinical Chemistry Alkaline phosphatase UC Davis IMPC 1.84E-5 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_CBC_014_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CBC_003¶meter_stable_id=IMPC_CBC_014_001&phenotyping_center=UC Davis abnormal startle reflex Tox homozygote female Early adult Combined SHIRPA and Dysmorphology Startle response UC Davis IMPC 2.2E-5 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_CSD_036_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_CSD_003¶meter_stable_id=IMPC_CSD_036_001&phenotyping_center=UC Davis abnormal auditory brainstem response Tox homozygote not_considered Early adult Auditory Brain Stem Response 12kHz-evoked ABR Threshold UC Davis IMPC 5.22E-5 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_ABR_006_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ABR_002¶meter_stable_id=IMPC_ABR_006_001&phenotyping_center=UC Davis abnormal auditory brainstem response Tox homozygote not_considered Early adult Auditory Brain Stem Response 6kHz-evoked ABR Threshold UC Davis IMPC 6.42E-5 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_ABR_004_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ABR_002¶meter_stable_id=IMPC_ABR_004_001&phenotyping_center=UC Davis abnormal auditory brainstem response Tox homozygote not_considered Early adult Auditory Brain Stem Response 18kHz-evoked ABR Threshold UC Davis IMPC 6.42E-5 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_ABR_008_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ABR_002¶meter_stable_id=IMPC_ABR_008_001&phenotyping_center=UC Davis abnormal auditory brainstem response Tox homozygote not_considered Early adult Auditory Brain Stem Response Click-evoked ABR threshold UC Davis IMPC 7.8E-5 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_ABR_002_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ABR_002¶meter_stable_id=IMPC_ABR_002_001&phenotyping_center=UC Davis prolonged RR interval Tox homozygote not_considered Early adult Electrocardiogram (ECG) RR UC Davis IMPC 8.87E-5 //www.mousephenotype.org/data/charts?accession=MGI:2181659&allele_accession_id=MGI:5605811&zygosity=homozygote¶meter_stable_id=IMPC_ECG_004_001&pipeline_stable_id=UCD_001&procedure_stable_id=IMPC_ECG_003¶meter_stable_id=IMPC_ECG_004_001&phenotyping_center=UC Davis