Gene: Brd4

Order

Name bromodomain containing 4

Synonyms
  • MCAP
  • HUNK1
  • WI-11513

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1888520    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Brd4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Brd4 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Brd4tm1b(EUCOMM)Wtsi HOM Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Brd4tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (2/2)
Bone 2 No (1/539) (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No (1/2)
Cartilage tissue 2 No (1/562) (2/2)
Cecum 2 No (1/355) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562)
Gall bladder 2 No (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562)
Mammary gland 2 No
Mesenteric lymph node 2 No
Olfactory lobe 2 No (4/393) (2/2)
Oral epithelium 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Parathyroid gland 2 No (2/540) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393) (1/2)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562) (1/2)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Testis 2 No (4/562) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Trigeminal V nerve 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vas deferens 2 No (1/360) (1/2)
Vascular system 2 No (1/393)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    4 Images
  • Eye Morphology: VIP of left fundus
    2 Images
  • X-ray: XRay Images Dorso Ventral
    4 Images
  • X-ray: XRay Images Forepaw
    4 Images
  • Adult LacZ: LacZ Images Wholemount
    14 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    4 Images
  • X-ray: XRay Images Skull Lateral Orientation
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Brd4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Brd4tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Brd4tm48673(L1L2_gt0)
Vector
Gene