Gene: Agpat1

Name 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)

Synonyms
  • Lpaat-alpha
  • 1-AGP

Status ES CellsMice
tm1.1
Mice
tm1
phenotype data available

Links MGI:1932075   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Subviable

Phenotype associations for Agpat1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Agpat1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Agpat1tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
decreased circulating glucose level Agpat1tm1.1(KOMP)Vlcg HET Female Male postnatal 3.32E-6
decreased circulating calcium level Agpat1tm1.1(KOMP)Vlcg HET Female Male postnatal 4.64E-6
increased heart rate variability Agpat1tm1.1(KOMP)Vlcg HET Male postnatal 1.3E-5
cardiovascular system phenotype Agpat1tm1.1(KOMP)Vlcg HET Female Male postnatal 1.57E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (2/2)
Bone marrow 2 No (2/2)
Brain 2 No (5/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (19/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393) (2/2)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No (2/2)
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (3/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (5/439) (2/3)
Dorsal root ganglion 1 Image Only
Ear 2 (1/3)
Embryo 2 (2/3)
Eye 2 (1/3)
Foot 2 (2/3)
Forebrain 2 (2/3)
Forelimb 2 (2/3)
Fronto-nasal process 1 Image Only
Hand 2 (2/3)
Head 2 (4/439) (2/3)
Heart 2 (2/3)
Hindbrain 2 (5/439) (2/3)
Hindlimb 2 (2/3)
Liver 2 (2/3)
Lung 2 Image Only
Mandibular process 2 (2/3)
Maxillary process 2 (2/3)
Midbrain 2 (2/3)
Nose 1 Image Only (1/1)
Oral cavity 2 (1/3)
Skin 2 (2/3)
Spinal cord 1 Image Only (1/1)
Tail 2 (2/3)
Tail somite 2 (2/3)


Associated Images

Associated Images
  • X-ray: XRay Images Skull Lateral Orientation
    12 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    12 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • Electroretinography 2: Rod and cone PDF
    3 Images
  • X-ray: XRay Images Dorso Ventral
    12 Images
  • X-ray: XRay Images Forepaw
    12 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Agpat1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Agpat1tm213685(L1L2_Bact_P)
Vector
Gene
Agpat1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene