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Phenotype: decreased KLRG1-positive T-helper cell number

Definition
reduction in the number of CD4-positive alpha-beta T-helper cells expressing KLRG1, a marker associated with activation
Synonyms
reduced KLRG1-positive T-helper cell number
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased KLRG1-positive T-helper cell number

Total number of significant genotype-phenotype associations: 2

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Sik3
Sik3tm1a(EUCOMM)Hmgu 		HOM   Early adult decreased KLRG1-positive T-helper cell number KLRG1+ CD4+ T helper cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Tmem127
Tmem127tm1(KOMP)Wtsi 		HOM   Early adult decreased KLRG1-positive T-helper cell number KLRG1+ CD4+ T helper cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00

Download data as:   TSV   XLS

 The way we measure

Procedure
Mesenteric Lymph Node Immunophenotyping
Spleen Immunophenotyping

 Phenotype associations stats

0.43% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased KLRG1-positive T-helper cell number (2/463)

0.00% females (0/4) 0.00% males (0/4)

Select a parameter    



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