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Phenotype: decreased Ly6C-positive NK T cell number

Definition
reduction in the number of NK T cells expressing the memory marker Ly6C
Synonyms
reduced Ly6C-positive NK T cell number,  decreased Ly6C-positive natural killer T cell number
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased Ly6C-positive NK T cell number

Total number of significant genotype-phenotype associations: 5

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Pepd
Pepdtm1a(KOMP)Wtsi 		HOM   Early adult decreased Ly6C-positive NK T cell number Ly6C+ NKT cells - % of lymphocytes
Spleen Immunophenotyping		 WTSI
3i		 0.00
Nub1
Nub1tm1b(EUCOMM)Hmgu 		HOM Early adult decreased Ly6C-positive NK T cell number NKT Subsets (Q1)
Immunophenotyping		 CCP-IMG
IMPC		 2.09×10-11
Arb2a
Arb2aem2(IMPC)Ccpcz 		HOM Early adult decreased Ly6C-positive NK T cell number NKT Subsets (Q3)
Immunophenotyping		 CCP-IMG
IMPC		 3.09×10-07
Ube3c
Ube3ctm1b(EUCOMM)Hmgu 		HOM Early adult decreased Ly6C-positive NK T cell number NKT Subsets (Q1)
Immunophenotyping		 HMGU
IMPC		 7.45×10-06

Download data as:   TSV   XLS

 The way we measure

Procedure
Immunophenotyping
FACS
Spleen Immunophenotyping

 Phenotype associations stats

0.95% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased Ly6C-positive NK T cell number (4/422)

2.70% females (2/74) 2.70% males (2/74)

Select a parameter    



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