IMPC Gene variants with decreased Ly6C-positive mature NK cell number
Total number of significant genotype-phenotype associations: 9
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
---|---|---|---|---|---|---|---|
Arpc1b Arpc1btm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased Ly6C-positive mature NK cell number | Ly6C+ mature NK cells - % of lymphocytes Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased Ly6C-positive mature NK cell number | Ly6C+ mature NK cells - % of mature NK cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Dph6 Dph6tm1a(KOMP)Wtsi |
HOM | Early adult | decreased Ly6C-positive mature NK cell number | Ly6C+ mature NK cells - % of mature NK cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased Ly6C-positive mature NK cell number | Ly6C+ mature NK cells - % of lymphocytes Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Rwdd1 Rwdd1tm1b(KOMP)Wtsi |
HOM | Early adult | decreased Ly6C-positive mature NK cell number | Ly6C+ mature NK cells - % of mature NK cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased Ly6C-positive mature NK cell number | Ly6C+ mature NK cells - % of lymphocytes Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Prkab1 Prkab1tm1b(KOMP)Wtsi |
HET | Early adult | decreased Ly6C-positive mature NK cell number | NK Subsets (Q4) Immunophenotyping |
CCP-IMG IMPC |
5.05×10-09 | |
Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased Ly6C-positive mature NK cell number | NK Subsets (Q2) Immunophenotyping |
HMGU IMPC |
3.12×10-06 | |
Tent5a Tent5aem1(IMPC)Ccpcz |
HOM | Early adult | decreased Ly6C-positive mature NK cell number | NK Subsets (Q2) Immunophenotyping |
CCP-IMG IMPC |
2.92×10-05 |