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Phenotype: decreased memory-marker CD4-positive NK T cell number

Definition
reduction in the number of memory-marker CD4-positive NK T cells with a CD44+ CD62L- phenotype
Synonyms
reduced memory-marker CD4-positive NK T cell number
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased memory-marker CD4-positive NK T cell number

Total number of significant genotype-phenotype associations: 11

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Arhgef1
Arhgef1tm1a(EUCOMM)Wtsi 		HOM   Early adult decreased memory-marker CD4-positive NK T cell number Resting CD4+ NKT cells - % of CD4+ NKT cells
Spleen Immunophenotyping		 WTSI
3i		 0.00
Clpp
Clpptm1a(EUCOMM)Wtsi 		HOM   Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi 		HOM   Early adult decreased memory-marker CD4-positive NK T cell number Resting CD4+ NKT cells - % of CD4+ NKT cells
Spleen Immunophenotyping		 WTSI
3i		 0.00
Gmds
Gmdstm1a(KOMP)Wtsi 		HOM   Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Sik3
Sik3tm1a(EUCOMM)Hmgu 		HOM   Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Tmem150b
Tmem150bem1(IMPC)Ccpcz 		HOM Early adult decreased memory-marker CD4-positive NK T cell number CD4 CD44+CD62L+ NKT cells
Immunophenotyping		 CCP-IMG
IMPC		 1.75×10-12
Cd38
Cd38em1(IMPC)Ccpcz 		HOM Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of live leukocytes (Panel A)
Immunophenotyping		 CCP-IMG
IMPC		 1.87×10-10
Ubd
Ubdtm1b(EUCOMM)Wtsi 		HOM Early adult decreased memory-marker CD4-positive NK T cell number CD4 CD44+CD62L+ NKT cells
Immunophenotyping		 CCP-IMG
IMPC		 1.59×10-09
Amelx
Amelxem1(IMPC)Ccpcz 		HEM Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of live leukocytes (Panel A)
Immunophenotyping		 CCP-IMG
IMPC		 3.53×10-05
Gpr83
Gpr83em1(IMPC)Ccpcz 		HOM Early adult decreased memory-marker CD4-positive NK T cell number Effector CD4+ NKT cells - % of live leukocytes (Panel A)
Immunophenotyping		 CCP-IMG
IMPC		 8.28×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Immunophenotyping
FACS
Mesenteric Lymph Node Immunophenotyping
Spleen Immunophenotyping

 Phenotype associations stats

1.29% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased memory-marker CD4-positive NK T cell number (10/778)

1.24% females (4/322) 0.63% males (2/319)

Select a parameter    



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