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Phenotype: increased CD4-negative NK T cell number

Definition
increase in the number of CD4-negative NK T cells
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased CD4-negative NK T cell number

Total number of significant genotype-phenotype associations: 19

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi 		HOM   Early adult increased memory-marker CD4-negative NK T cell number Effector CD4- NKT cells - % of CD4- NKT cells
Mesenteric Lymph Node Immunophenotyping		 WTSI
3i		 0.00
Bach2
Bach2tm1a(EUCOMM)Wtsi 		HOM   Early adult increased memory-marker CD4-negative NK T cell number Effector CD4- NKT cells - % of CD4- NKT cells
Spleen Immunophenotyping		 WTSI
3i		 0.00
Bach2
Bach2tm1a(EUCOMM)Wtsi 		HOM   Early adult increased KLRG1-positive CD4-negative NK T cell number KLRG1+ CD4- NKT cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi 		HOM   Early adult increased CD4-negative NK T cell number Total CD4- NKT cells - % of NKT cells
Spleen Immunophenotyping		 WTSI
3i		 0.00
Dph6
Dph6tm1a(KOMP)Wtsi 		HOM   Early adult increased memory-marker CD4-negative NK T cell number Resting CD4- NKT cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Gimap6
Gimap6tm1a(KOMP)Wtsi 		HOM   Early adult increased memory-marker CD4-negative NK T cell number Resting CD4- NKT cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Gmds
Gmdstm1a(KOMP)Wtsi 		HOM   Early adult increased CD4-negative NK T cell number Total CD4- NKT cells - % of NKT cells
Spleen Immunophenotyping		 WTSI
3i		 0.00
Pepd
Pepdtm1a(KOMP)Wtsi 		HOM   Early adult increased memory-marker CD4-negative NK T cell number Resting CD4- NKT cells - % of CD45+
Mesenteric Lymph Node Immunophenotyping		 WTSI
3i		 0.00
Prkab1
Prkab1tm1b(KOMP)Wtsi 		HOM   Early adult increased memory-marker CD4-negative NK T cell number Effector CD4- NKT cells - % of CD45+
Spleen Immunophenotyping		 WTSI
3i		 0.00
Sik3
Sik3tm1a(EUCOMM)Hmgu 		HOM   Early adult increased KLRG1-positive CD4-negative NK T cell number KLRG1+ CD4- NKT cells - % of CD45+
Mesenteric Lymph Node Immunophenotyping		 WTSI
3i		 0.00
Sik3
Sik3tm1a(EUCOMM)Hmgu 		HOM   Early adult increased CD4-negative NK T cell number Total CD4- NKT cells - % of NKT cells
Spleen Immunophenotyping		 WTSI
3i		 0.00
Bach2
Bach2tm1b(EUCOMM)Wtsi 		HOM Early adult increased memory-marker CD4-negative NK T cell number DN CD44+CD62L+ NKT cells
Immunophenotyping		 HMGU
IMPC		 7.36×10-11
Bahd1
Bahd1tm2b(KOMP)Wtsi 		HET Early adult increased CD4-negative NK T cell number DN NKT cells
Immunophenotyping		 ICS
IMPC		 1.63×10-06
Bahd1
Bahd1tm2b(KOMP)Wtsi 		HET Early adult increased memory-marker CD4-negative NK T cell number DN CD44+CD62L- NKT cells
Immunophenotyping		 ICS
IMPC		 6.66×10-06
Lgr5
Lgr5em1(IMPC)Kmpc 		HET   Early adult increased CD4-negative, CD25-positive NK T cell number DN CD25+ NKT cells
Immunophenotyping		 KMPC
IMPC		 5.38×10-05
Pip4p1
Pip4p1em1(IMPC)Ccpcz 		HOM   Early adult increased CD4-negative, CD25-positive NK T cell number DN CD25+ NKT cells
Immunophenotyping		 CCP-IMG
IMPC		 8.23×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Immunophenotyping
FACS
Mesenteric Lymph Node Immunophenotyping
Spleen Immunophenotyping

 Phenotype associations stats

2.23% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased CD4-negative NK T cell number (12/538)

2.25% females (2/89) 2.33% males (2/86)

Select a parameter    



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