MP:0013426 (decreased memory-marker NK cell number) | IMPC Phenotype Information | International Mouse Phenotyping Consortium

Phenotype: decreased memory-marker NK cell number

Definition

reduction in the number of memory-marker NK cells with a CD44+ CD62L- phenotype

Synonyms

reduced memory-marker NK cell number

of tested genes

significant genes

tested genes

Total number of significant genotype-phenotype associations: 6

Gene / Allele	Zygosity	Life Stage	Phenotype	Parameter	Phenotyping Center
Adap1 Adap1^{tm1a(EUCOMM)Wtsi}	HOM	Early adult	decreased memory-marker NK cell number	Resting NK cells - % of CD45+ Spleen Immunophenotyping	WTSI 3i
Bach2 Bach2^{tm1a(EUCOMM)Wtsi}	HOM	Early adult	decreased memory-marker NK cell number	Resting NK cells - % of CD45+ Spleen Immunophenotyping	WTSI 3i
Cog6 Cog6^{tm1a(EUCOMM)Wtsi}	HOM	Early adult	decreased memory-marker NK cell number	Effector NK cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping	WTSI 3i
D6Wsu163e D6Wsu163e^{tm1b(EUCOMM)Wtsi}	HOM	Early adult	decreased memory-marker NK cell number	Resting NK cells - % of NK cells Mesenteric Lymph Node Immunophenotyping	WTSI 3i
Fbxw26 Fbxw26^{tm1b(KOMP)Wtsi}	HOM	Early adult	decreased memory-marker NK cell number	Resting NK cells - % of CD45+ Spleen Immunophenotyping	WTSI 3i
Tmem127 Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	decreased memory-marker NK cell number	Effector NK cells - % of CD45+ Spleen Immunophenotyping	WTSI 3i

Download data as: TSV XLS

Procedure
Mesenteric Lymph Node Immunophenotyping
Spleen Immunophenotyping

1.30% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased memory-marker NK cell number (6/463)

0.00% females (0/8) 0.00% males (0/8)

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