Phenotype: abnormal head shape

Definition any anomaly in the characteristic surface outline or contour of a head of an organism

Related
Synonyms
  • midface hypoplasia
  • midface hypoplasia
  • Hemifacial hypoplasia
  • Hemifacial hypoplasia
  • Acrobrachycephaly
  • Hemifacial atrophy
  • shortened head
  • Hemifacial hypoplasia
  • broad head
  • Skull asymmetry
  • otocephaly
  • Proboscis
  • hemifacial hypoplasia
  • proboscis
  • Brachyturricephaly
  • Brachycephaly
  • hemifacial hypoplasia
  • hemifacial hypoplasia
  • Posterior plagiocephaly
  • Hemifacial hypoplasia
  • Hemifacial hypertrophy
  • Hemifacial hypertrophy
  • Anterior plagiocephaly
  • round head
  • Acrobrachycephaly
  • Anterior plagiocephaly
  • Asymmetric crying face
  • craniofacial asymmetry
  • facial asymmetry
  • Hemifacial hypertrophy
  • trigonocephaly
  • Asymmetry of the maxilla
  • midface retrusion
  • Asymmetric crying face
  • Hemifacial atrophy
  • Hemifacial hypoplasia
  • Hemifacial atrophy
  • Asymmetric crying face
  • Midface retrusion
  • narrow head
  • Craniofacial asymmetry
  • flat head
  • Hemifacial hypertrophy
  • Plagiocephaly
  • Asymmetry of the mandible
  • Hemifacial atrophy
  • Facial asymmetry
  • Trigonocephaly
  • Posterior plagiocephaly
  • hemifacial hypoplasia
  • Brachyturricephaly
  • Asymmetric crying face
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MP browserMP:0011495

Phenotype associations stats

2.63% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal head shape (12/456)

2.51% females (11/438) 1.79% males (8/447)

Gene variants with abnormal head shape

Total number of significant genotype-phenotype associations: 23

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Anapc15
Anapc15tm1.1(KOMP)Vlcg
HOM Female embryonic day 15.5 abnormal head shape Gross Morphology Embryo E14.5-E15.5 | Head shape JAX | IMPC 0.0
Axin2
Axin2tm1b(KOMP)Wtsi
HET Female embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape BCM | IMPC 0.0
Axin2
Axin2tm1b(KOMP)Wtsi
HOM Female Male embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape BCM | IMPC 0.0
Eya1
Eya1tm1b(EUCOMM)Hmgu
HOM Female Male embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape BCM | IMPC 0.0
Kcnj13
Kcnj13tm1b(KOMP)Wtsi
HOM Female Male embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape BCM | IMPC 0.0
Kif1b
Kif1btm1b(KOMP)Wtsi
HOM Female Male embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape JAX | IMPC 0.0
Nxn
Nxnem1(IMPC)Bay
HOM Female Male embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape BCM | IMPC 0.0
Nxn
Nxntm1b(EUCOMM)Wtsi
HOM Female Male embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape BCM | IMPC 0.0
Slc35d1
Slc35d1tm2b(EUCOMM)Hmgu
HOM Female Male embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape BCM | IMPC 0.0
Snx3
Snx3tm1.1(KOMP)Vlcg
HOM Female Male embryonic day 15.5 abnormal head shape Gross Morphology Embryo E14.5-E15.5 | Head shape JAX | IMPC 0.0
Snx3
Snx3tm1.1(KOMP)Vlcg
HOM Female embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape JAX | IMPC 0.0
Tmem132a
Tmem132atm1b(KOMP)Wtsi
HOM Male embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape BCM | IMPC 0.0
Trib1
Trib1tm1b(KOMP)Wtsi
HOM Female embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape BCM | IMPC 0.0
Usf3
Usf3tm2b(EUCOMM)Wtsi
HOM Female embryonic day 18.5 abnormal head shape Gross Morphology Embryo E18.5 | Head shape BCM | IMPC 0.0
Wdr59
Wdr59tm1b(EUCOMM)Wtsi
HOM Female embryonic day 15.5 abnormal head shape Gross Morphology Embryo E14.5-E15.5 | Head shape BCM | IMPC 0.0

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Images

  • Prmt3tm1a(EUCOMM)Wtsi
    abnormal snout morphology, abnormal head shape, HOM, Male, WTSI
  • Pthlhtm1a(KOMP)Wtsi
    abnormal head shape, HET, Female, WTSI
  • Pthlhtm1a(KOMP)Wtsi
    abnormal head shape, HET, Female, WTSI
  • Pthlhtm1a(KOMP)Wtsi
    abnormal head shape, HET, Female, WTSI
  • Zfp879tm2b(KOMP)Wtsi
    HEAD, abnormal head shape, HOM, Male, WTSI