Phenotype: decreased heart left ventricle size

Definition less than average size of the left ventricle compared to the average for a particular population

Synonyms
  • reduced left ventricle size
  • reduced left ventricle size
  • decreased left ventricle size
  • decreased left ventricle size
Related
Synonyms
  • LV hypoplasia
  • LV hypoplasia
  • decreased heart left ventricle weight
  • decreased heart left ventricle weight
  • decreased left ventricle weight
  • heart left ventricle hypoplasia
  • hypoplastic LV
  • reduced left ventricle weight
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MP browserMP:0010580

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Phenotype associations stats

2.71% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased heart left ventricle size (30/1108)

2.64% females (29/1099) 3.47% males (29/835)

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Gene variants with decreased heart left ventricle size

Total number of significant genotype-phenotype associations: 64

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Map3k10
Map3k10tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 1.32E-17
Pcx
Pcxtm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 1.39E-12
Dbn1
Dbn1tm1b(KOMP)Wtsi
HET Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 5.88E-12
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 3.23E-9
Fyb
Fybtm1b(EUCOMM)Hmgu
HOM Female postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 1.17E-8
Suv39h2
Suv39h2em1Marc
HOM Male postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 2.45E-8
Ints6l
Ints6lem1Marc
HEM Male postnatal decreased heart left ventricle size Echo | LVPWs MARC | IMPC 4.08E-8
Ints6l
Ints6lem1Marc
HOM Female postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 3.83E-7
Phf21b
Phf21bem1Marc
HOM Female Male postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 4.04E-7
Dnajc17
Dnajc17tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 6.68E-7
Entpd1
Entpd1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 7.2E-7
Lsm1
Lsm1tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 1.56E-6
Gad2
Gad2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 3.81E-6
Abcb11
Abcb11tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 5.71E-6
Abcb11
Abcb11tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 5.71E-6
Ube2z
Ube2zem1Marc
HET Female Male postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 6.25E-6
Prmt6
Prmt6em1Marc
HOM Female Male postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 6.28E-6
Btbd9
Btbd9tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 8.81E-6
Vav2
Vav2em1Marc
HOM Female Male postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 1.01E-5
Kdm2b
Kdm2bem1Marc
HET Female Male postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 1.19E-5
Rest
Resttm2b(EUCOMM)Wtsi
HET Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 1.22E-5
Ccdc83
Ccdc83em1Marc
HOM Female Male postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 1.74E-5
Cenpe
Cenpetm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 2.57E-5
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 2.71E-5
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
HOM Female Male postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 2.71E-5
Gbp2
Gbp2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 2.82E-5
Siva1
Siva1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 3.1E-5
Gsdmd
Gsdmdem1Marc
HOM Female Male postnatal decreased heart left ventricle size Echo | LVPWs MARC | IMPC 3.36E-5
Esr2
Esr2em1Marc
HOM Female Male postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 3.36E-5
Hilpda
Hilpdaem1Mhzh
HOM Female Male postnatal decreased heart left ventricle size Echo | LVPWs MARC | IMPC 6.0E-5
Nfatc3
Nfatc3tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 6.46E-5
Trim37
Trim37em1Marc
HOM Female Male postnatal decreased heart left ventricle size Echo | LVPWs MARC | IMPC 6.49E-5
Ppp2r5e
Ppp2r5eem1Marc
HOM Female Male postnatal decreased heart left ventricle size Echo | LVAWd MARC | IMPC 7.97E-5
Entpd1
Entpd1tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased heart left ventricle size Echo | LVPWs HMGU | IMPC 9.36E-5

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