Phenotype: shortened PR interval

Definition decrease in the length of time between the beginning of atrial depolarization and the beginning of ventricular depolarization, measured by the interval from the beginning of the P wave to the beginning of the QRS complex

Synonyms
  • decreased PR interval
  • decreased PR interval
  • reduced PR interval
  • reduced PR interval

MP browserMP:0010511

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Phenotype associations stats

0.24% of tested genes with null mutations on a B6N genetic background have a phenotype association to shortened PR interval (6/2455)

0.16% females (4/2451) 0.24% males (6/2453)



Gene variants with shortened PR interval

Total number of significant genotype-phenotype associations: 10

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Kcng2
Kcng2em2Bay
HOM Female Male postnatal shortened PR interval Electrocardiogram (ECG) | PR BCM | IMPC 9.62E-13
Sorbs2
Sorbs2tm1.1(KOMP)Mbp
HOM Female Male postnatal shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 8.57E-8
Sycp3
Sycp3tm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 9.76E-6
Cldn19
Cldn19tm1.1(KOMP)Vlcg
HOM Female Male postnatal shortened PR interval Electrocardiogram (ECG) | PR JAX | IMPC 9.88E-6
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Male postnatal shortened PR interval Electrocardiogram (ECG) | PR MRC Harwell | IMPC 1.07E-5
Gpbp1
Gpbp1tm1b(EUCOMM)Wtsi
HET Male postnatal shortened PR interval Electrocardiogram (ECG) | PR HMGU | IMPC 5.53E-5

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