Definition
reduced number of a type of transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, and is located in the splenic B follicles
Synonyms
decreased transitional two stage B-cell number,
decreased transitional two stage B-lymphocyte number,
reduced T2 stage B cell number,
reduced transitional two stage B-lymphocyte number,
decreased T2 stage B cell number,
reduced transitional two stage B-cell number,
reduced transitional two stage B lymphocyte number,
decreased transitional two stage B lymphocyte number
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with decreased transitional stage T2 B cell number
Total number of significant genotype-phenotype associations: 3
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Arpc1b Arpc1btm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased transitional stage T2 B cell number | Transitional 2 B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased transitional stage T2 B cell number | Transitional 2 B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased transitional stage T2 B cell number | Transitional 2 B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 |