Definition
greater number of a cells of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with increased dendritic cell number
Total number of significant genotype-phenotype associations: 17
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Arhgef1 Arhgef1tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased plasmacytoid dendritic cell number | Plasmacytoid DC - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Arpc1b Arpc1btm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD103-positive CD11b-low dendritic cell number | CD103+ CD11b-low cDC - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD103-positive CD11b-low dendritic cell number | CD103+ CD11b-low cDC - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD11b-low dendritic cell number | CD11b-low cDC - % of cDC Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Cxcr2 Cxcr2tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD103-positive CD11b-low dendritic cell number | CD103+ CD11b-low cDC - % of CD11b-low cDC Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Dph6 Dph6tm1a(KOMP)Wtsi |
HOM | Early adult | increased dendritic cell number | Total DC - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Dph6 Dph6tm1a(KOMP)Wtsi |
HOM | Early adult | increased CD11b-low dendritic cell number | CD11b-low cDC - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Dph6 Dph6tm1a(KOMP)Wtsi |
HOM | Early adult | increased plasmacytoid dendritic cell number | Plasmacytoid DC - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | increased plasmacytoid dendritic cell number | Plasmacytoid DC - % of DC Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Pclaf Pclaftm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD11b-low dendritic cell number | CD11b-low cDC - % of cDC Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Pclaf Pclaftm1a(EUCOMM)Wtsi |
HOM | Early adult | increased dendritic cell number | Conventional DC (cDC) - % of DC Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | increased plasmacytoid dendritic cell number | Plasmacytoid DC - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Trappc9 Trappc9tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased CD11b-high dendritic cell number | CD11b-high cDC - % of cDC Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Lgr5 Lgr5em1(IMPC)Kmpc |
HET | Early adult | increased CD11b-high dendritic cell number | cDCs CD11b Type Immunophenotyping |
KMPC IMPC |
7.90×10-06 | |
| Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased CD11b-high dendritic cell number | cDCs CD11b Type Immunophenotyping |
ICS IMPC |
1.97×10-05 | |
| Asb2 Asb2tm2b(KOMP)Wtsi |
HET | Early adult | increased dendritic cell number | cDCs Immunophenotyping |
KMPC IMPC |
4.92×10-05 | |
| Alkbh1 Alkbh1tm1b(EUCOMM)Hmgu |
HET | Late adult | increased plasmacytoid dendritic cell number | pDCs Immunophenotyping |
HMGU IMPC |
9.18×10-05 |