Phenotype: increased plasma cell number

Definition
greater number of terminally differentiated, post-mitotic, short-lived cells of the B cell lineage devoted to producing large amounts of immunoglobulin
Synonyms
plasma cell hyperplasia
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased plasma cell number

Total number of significant genotype-phenotype associations: 4

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM   Early adult increased plasma cell number Plasma cells - % of B2 cells
Mesenteric Lymph Node Immunophenotyping
WTSI
3i
0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM   Early adult increased plasma cell number Plasma cells - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00
Cttnbp2
Cttnbp2tm1b(KOMP)Wtsi
HOM   Early adult increased plasma cell number Plasma cells - % of CD45+
Bone marrow immunophenotyping
WTSI
3i
0.00
Dph6
Dph6tm1a(KOMP)Wtsi
HOM   Early adult increased plasma cell number Plasma cells - % of CD45+
Spleen Immunophenotyping
WTSI
3i
0.00

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

1.08% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased plasma cell number (4/370)

0.00% females (0/4) 0.00% males (0/4)

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