Definition
fewer than normal T cell numbers
Synonyms
reduced T-lymphocyte number,
reduced T-cell count,
decreased T-cell number,
decreased T cell count,
reduced T cell number,
reduced T lymphocyte number,
decreased T-cell count,
reduced T-cell number
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with decreased T cell number
Total number of significant genotype-phenotype associations: 196
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Arhgef1 Arhgef1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker gamma-delta T cell number | Resting gd T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Arhgef1 Arhgef1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker CD4-positive NK T cell number | Resting CD4+ NKT cells - % of CD4+ NKT cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Arhgef1 Arhgef1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Arpc1b Arpc1btm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | CD4+ alpha beta T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased effector memory CD8-positive, alpha-beta T cell number | Resting CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased regulatory T cell number | CD4+ CD25+ alpha beta regulatory T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Brd2 Brd2em1(IMPC)Wtsi |
HET | Early adult | decreased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of ab T cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Cd28 Cd28tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased T cell number | CD25+ percentage of CD4+ T cells FACs Analysis |
MRC Harwell EuroPhenome |
0.00 | |
| Clpp Clpptm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker CD4-positive NK T cell number | Effector CD4+ NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Clpp Clpptm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Effector CD4- NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Clpp Clpptm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased effector memory CD8-positive, alpha-beta T cell number | Effector CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Clpp Clpptm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-positive NK T cell number | Total CD4+ NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Clpp Clpptm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased NK T cell number | Total NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Clpp Clpptm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased gamma-delta T cell number | Gamma delta T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased effector memory CD8-positive, alpha-beta T cell number | Resting CD8+ T cells - % of CD8+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker gamma-delta T cell number | Resting gd T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased NK T cell number | Total NKT cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T-helper cell number | CD4+ T helper cells - % of CD4+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker CD4-positive NK T cell number | Resting CD4+ NKT cells - % of CD4+ NKT cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Resting CD4- NKT cells - % of CD4- NKT cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-positive NK T cell number | Total CD4+ NKT cells - % of NKT cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased alpha-beta T cell number | Alpha beta T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T cell number | Total T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Cxcr2 Cxcr2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T cell number | T cells - % of CD45+ Bone marrow immunophenotyping |
WTSI 3i |
0.00 | |
| Cxcr2 Cxcr2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of ab T cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| D6Wsu163e D6Wsu163etm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | Total CD4+ T cells - % of ab T cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Dph6 Dph6tm1a(KOMP)Wtsi |
HOM | Early adult | decreased effector memory CD8-positive, alpha-beta T cell number | Resting CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Dph6 Dph6tm1a(KOMP)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of ab T cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Dph6 Dph6tm1a(KOMP)Wtsi |
HOM | Early adult | decreased NK T cell number | Total NKT cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Dph6 Dph6tm1a(KOMP)Wtsi |
HOM | Early adult | decreased T-helper cell number | CD4+ T helper cells - % of CD4+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | decreased memory-marker gamma-delta T cell number | Effector gd T cells - % of gd T cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Resting Treg cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of ab T cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gda Gdatm1a(KOMP)Wtsi |
HOM | Early adult | decreased T-helper cell number | CD4+ T helper cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Gimap6 Gimap6tm1a(KOMP)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Effector CD4- NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gimap6 Gimap6tm1a(KOMP)Wtsi |
HOM | Early adult | decreased CD4-negative NK T cell number | Total CD4- NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased KLRG1+ CD8 alpha-beta T cell number | KLRG1+ CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of ab T cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased T-helper cell number | CD4+ T helper cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased memory-marker CD4-positive NK T cell number | Effector CD4+ NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Effector Treg cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Resting CD4- NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased effector memory CD8-positive, alpha-beta T cell number | Resting CD8+ T cells - % of CD8+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased CD4-positive NK T cell number | Total CD4+ NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | Total CD4+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Total Treg cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased alpha-beta T cell number | Total ab T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased regulatory T cell number | CD4+ CD25+ alpha beta regulatory T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Hbs1l Hbs1ltm1a(KOMP)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Resting CD4- NKT cells - % of CD4- NKT cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Hbs1l Hbs1ltm1a(KOMP)Wtsi |
HOM | Early adult | decreased effector memory CD8-positive, alpha-beta T cell number | Resting CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Hbs1l Hbs1ltm1a(KOMP)Wtsi |
HOM | Early adult | decreased T-helper cell number | CD4+ T helper cells - % of CD4+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Il27 Il27tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta memory T cell number | CD4+ CD44+ CD62L- alpha beta effector T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Irf5 Irf5tm1e(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta memory T cell number | CD4+ CD44+ CD62L- alpha beta effector T cell number Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Mkrn2 Mkrn2tm1b(KOMP)Wtsi |
HOM | Early adult | decreased dendritic epidermal T cell number | DETC coverage Ear epidermis immunophenotyping |
WTSI 3i |
0.00 | |
| Ncf2 Ncf2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased alpha-beta T cell number | Alpha beta T cell number Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Ncf2 Ncf2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased regulatory T cell number | CD4+ CD25+ alpha beta regulatory T cell number Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Ncf2 Ncf2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased NK T cell number | NKT cell number Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Ncf2 Ncf2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T cell number | Total T cell number Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Nrbp1 Nrbp1tm3b(EUCOMM)Wtsi |
HET | Early adult | decreased CD4-positive, alpha-beta T cell number | Total CD4+ T cells - % of ab T cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Pclaf Pclaftm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T cell number | T cells - % of CD45+ Bone marrow immunophenotyping |
WTSI 3i |
0.00 | |
| Pclaf Pclaftm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased regulatory T cell number | CD4+ CD25+ alpha beta regulatory T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Pepd Pepdtm1a(KOMP)Wtsi |
HOM | Early adult | decreased Ly6C-positive NK T cell number | Ly6C+ NKT cells - % of lymphocytes Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Rwdd1 Rwdd1tm1b(KOMP)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of ab T cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Rwdd1 Rwdd1tm1b(KOMP)Wtsi |
HOM | Early adult | decreased regulatory T cell number | CD4+ CD25+ alpha beta regulatory T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Sgsm1 Sgsm1tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | Total CD4+ T cells - % of ab T cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased T-helper cell number | CD4+ T helper cells - % of CD4+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased CD5-positive gamma-delta T cell number | CD5+ gd T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased memory-marker CD4-positive NK T cell number | Effector CD4+ NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | Resting CD4- NKT cells - % of CD4- NKT cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased CD4-positive NK T cell number | Total CD4+ NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | Total CD4+ T cells - % of ab T cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased NK T cell number | Total NKT cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased gamma-delta T cell number | Total gd T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased alpha-beta T cell number | Alpha beta T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased regulatory T cell number | CD4+ CD25+ alpha beta regulatory T cell number Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased T cell number | Total T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Tmem126a Tmem126atm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T-helper cell number | CD4+ T helper cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Tmem126a Tmem126atm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | Total CD4+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Tmem126a Tmem126atm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased alpha-beta T cell number | Total ab T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Tmem127 Tmem127tm1(KOMP)Wtsi |
HOM | Early adult | decreased effector memory CD8-positive, alpha-beta T cell number | Resting CD8+ T cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Tmem127 Tmem127tm1(KOMP)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | Total CD4+ T cells - % of ab T cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Traf2 Traf2tm1a(EUCOMM)Wtsi |
HET | Early adult | decreased CD8-positive, alpha-beta T cell number | Total CD8+ T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Traf2 Traf2tm1a(EUCOMM)Wtsi |
HET | Early adult | decreased alpha-beta T cell number | Total ab T cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Trappc9 Trappc9tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased gamma-delta T cell number | Gamma delta T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Trim56 Trim56tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased regulatory T cell number | CD4+ CD25+ alpha beta regulatory T cell percentage Whole blood peripheral blood leukocyte immunophenotyping |
WTSI 3i |
0.00 | |
| Vps13a Vps13atm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased T-helper cell number | CD4+ T helper cells - % of CD4+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Card11 Card11em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Treg cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
3.18×10-36 | |
| Psmb11 Psmb11em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
8.65×10-21 | |
| Cd38 Cd38em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Treg cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
4.30×10-20 | |
| Elk4 Elk4tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | T cell CD4+ percentage FACs Analysis |
HMGU EuroPhenome |
2.71×10-16 | |
| Elk4 Elk4tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T cell number | T cell CD3+ percentage FACs Analysis |
HMGU EuroPhenome |
1.14×10-13 | |
| Tmem150b Tmem150bem1(IMPC)Ccpcz |
HOM | Early adult | decreased memory-marker CD4-positive NK T cell number | CD4 CD44+CD62L+ NKT cells Immunophenotyping |
CCP-IMG IMPC |
1.75×10-12 | |
| Nub1 Nub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased Ly6C-positive NK T cell number | NKT Subsets (Q1) Immunophenotyping |
CCP-IMG IMPC |
2.09×10-11 | |
| Nub1 Nub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased NK T cell number | NKT Cells (panel B) Immunophenotyping |
CCP-IMG IMPC |
1.33×10-10 | |
| Cd38 Cd38em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD4-positive NK T cell number | CD4+ NKT cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
1.57×10-10 | |
| Cd38 Cd38em1(IMPC)Ccpcz |
HOM | Early adult | decreased memory-marker CD4-positive NK T cell number | Effector CD4+ NKT cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
1.87×10-10 | |
| Elk4 Elk4tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
HMGU EuroPhenome |
6.47×10-10 | |
| Cd38 Cd38em1(IMPC)Ccpcz |
HOM | Early adult | decreased NK T cell number | NKT cells (panel A) - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
1.00×10-09 | |
| Card11 Card11em1(IMPC)Ccpcz |
HOM | Early adult | decreased effector memory CD8-positive, alpha-beta T cell number | Naïve CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
1.12×10-09 | |
| Ubd Ubdtm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker CD4-positive NK T cell number | CD4 CD44+CD62L+ NKT cells Immunophenotyping |
CCP-IMG IMPC |
1.59×10-09 | |
| Usp12 Usp12tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
HMGU EuroPhenome |
1.75×10-09 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-negative NK T cell number | DN NKT cells Immunophenotyping |
HMGU IMPC |
2.44×10-09 | |
| Nr1d2 Nr1d2tm1Dgen |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
ICS EuroPhenome |
4.92×10-09 | |
| Apbb1ip Apbb1ipem1(IMPC)Ccpcz |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
5.40×10-08 | |
| Nr1d2 Nr1d2tm1Dgen |
HOM | Early adult | decreased T cell number | T cell CD3+ percentage FACs Analysis |
ICS EuroPhenome |
8.21×10-08 | |
| Acp2 Acp2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T cell number | T cell CD3+ percentage FACs Analysis |
MRC Harwell EuroPhenome |
9.34×10-08 | |
| Acp2 Acp2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
MRC Harwell EuroPhenome |
1.26×10-07 | |
| Cd27 Cd27em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number | Treg cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
2.16×10-07 | |
| Arb2a Arb2aem2(IMPC)Ccpcz |
HOM | Early adult | decreased Ly6C-positive NK T cell number | NKT Subsets (Q3) Immunophenotyping |
CCP-IMG IMPC |
3.09×10-07 | |
| Parvb Parvbtm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T cell number | CD25+ percentage of CD4+ T cells FACs Analysis |
MRC Harwell EuroPhenome |
3.12×10-07 | |
| Fam234b Fam234btm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
HMGU EuroPhenome |
3.98×10-07 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased NK T cell number | NKT cells (panel A) Immunophenotyping |
HMGU IMPC |
5.91×10-07 | |
| Cpm Cpmem1(IMPC)Ccpcz |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
8.07×10-07 | |
| Nub1 Nub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | CD8 T cells Immunophenotyping |
CCP-IMG IMPC |
1.08×10-06 | |
| Abcg8 Abcg8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | CD4 T cells Immunophenotyping |
CCP-IMG IMPC |
1.76×10-06 | |
| Krtap8-1 Krtap8-1em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | CD4 T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
2.98×10-06 | |
| Gper1 Gper1tm1Dgen |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | T cell CD4+ percentage FACs Analysis |
HMGU EuroPhenome |
3.45×10-06 | |
| Gper1 Gper1tm1Dgen |
HOM | Early adult | decreased T cell number | T cell CD3+ percentage FACs Analysis |
HMGU EuroPhenome |
3.84×10-06 | |
| Tmprss6 Tmprss6tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | CD8 T cells Immunophenotyping |
ICS IMPC |
3.88×10-06 | |
| Abcg8 Abcg8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | DN CD44+CD62L- NKT cells Immunophenotyping |
CCP-IMG IMPC |
3.94×10-06 | |
| Krtap8-1 Krtap8-1em1(IMPC)Ccpcz |
HOM | Early adult | decreased T-helper cell number | CD4+ T helper cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
5.51×10-06 | |
| Abcg8 Abcg8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased CD4-negative NK T cell number | DN NKT cells Immunophenotyping |
CCP-IMG IMPC |
6.14×10-06 | |
| Nub1 Nub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased CD4-negative NK T cell number | DN NKT cells Immunophenotyping |
CCP-IMG IMPC |
6.17×10-06 | |
| Nub1 Nub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | CD4 T cells Immunophenotyping |
CCP-IMG IMPC |
6.63×10-06 | |
| Asb7 Asb7em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
7.21×10-06 | |
| Ube3c Ube3ctm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased Ly6C-positive NK T cell number | NKT Subsets (Q1) Immunophenotyping |
HMGU IMPC |
7.45×10-06 | |
| Aldh2 Aldh2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
MRC Harwell EuroPhenome |
7.68×10-06 | |
| Abcg8 Abcg8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased T cell number | T Cells (panel B) Immunophenotyping |
CCP-IMG IMPC |
7.77×10-06 | |
| Nub1 Nub1tm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | DN CD44+CD62L- NKT cells Immunophenotyping |
CCP-IMG IMPC |
1.22×10-05 | |
| Usp12 Usp12tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased T cell number | T cell CD3+ percentage FACs Analysis |
HMGU EuroPhenome |
1.43×10-05 | |
| Atad2b Atad2btm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased NK T cell number | NKT Cells (panel B) Immunophenotyping |
ICS IMPC |
1.44×10-05 | |
| Cd38 Cd38em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | CD4 T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
1.45×10-05 | |
| Abcg8 Abcg8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | CD8 T cells Immunophenotyping |
CCP-IMG IMPC |
1.71×10-05 | |
| Acp2 Acp2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | T cell CD4+ percentage FACs Analysis |
MRC Harwell EuroPhenome |
1.80×10-05 | |
| Bahd1 Bahd1tm2b(KOMP)Wtsi |
HET | Early adult | decreased effector memory CD8-positive, alpha-beta T cell number | CD8 CD44+CD62L+ T cells Immunophenotyping |
ICS IMPC |
1.91×10-05 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased memory-marker CD4-negative NK T cell number | DN CD44+CD62L- NKT cells Immunophenotyping |
HMGU IMPC |
2.16×10-05 | |
| Rnase10 Rnase10tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | T cell CD4+ percentage FACs Analysis |
ICS EuroPhenome |
2.19×10-05 | |
| Gpr83 Gpr83em1(IMPC)Ccpcz |
HOM | Early adult | decreased NK T cell number | NKT cells (panel A) - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
2.27×10-05 | |
| Serf1 Serf1tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
MRC Harwell EuroPhenome |
2.30×10-05 | |
| Arhgef4 Arhgef4tm1a(KOMP)Wtsi |
HOM | Early adult | decreased T cell number | CD25+ percentage of CD4+ T cells FACs Analysis |
HMGU EuroPhenome |
2.32×10-05 | |
| Tnfrsf1b Tnfrsf1btm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T cell number | T cell CD3+ percentage FACs Analysis |
ICS EuroPhenome |
2.88×10-05 | |
| Rnase10 Rnase10tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
ICS EuroPhenome |
3.07×10-05 | |
| Cd38 Cd38em1(IMPC)Ccpcz |
HOM | Early adult | decreased T-helper cell number | CD4+ T helper cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
3.33×10-05 | |
| Amelx Amelxem1(IMPC)Ccpcz |
HEM | Early adult | decreased CD4-positive NK T cell number | CD4+ NKT cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
3.43×10-05 | |
| Amelx Amelxem1(IMPC)Ccpcz |
HEM | Early adult | decreased memory-marker CD4-positive NK T cell number | Effector CD4+ NKT cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
3.53×10-05 | |
| Rcc1l Rcc1ltm1a(EUCOMM)Hmgu |
HET | Early adult | decreased T cell number | CD25+ percentage of CD4+ T cells FACs Analysis |
HMGU EuroPhenome |
3.72×10-05 | |
| Aldh2 Aldh2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T cell number | T cell CD3+ percentage FACs Analysis |
MRC Harwell EuroPhenome |
3.81×10-05 | |
| Amelx Amelxem1(IMPC)Ccpcz |
HEM | Early adult | decreased NK T cell number | NKT cells (panel A) - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
3.86×10-05 | |
| Prss50 Prss50tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
MRC Harwell EuroPhenome |
3.89×10-05 | |
| Gper1 Gper1tm1Dgen |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
HMGU EuroPhenome |
4.19×10-05 | |
| Prpsap2 Prpsap2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
ICS EuroPhenome |
4.23×10-05 | |
| Mfng Mfngem1(IMPC)Ccpcz |
HOM | Early adult | decreased NK T cell number | NKT cells (panel A) - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
4.47×10-05 | |
| Rc3h2 Rc3h2tm1a(KOMP)Wtsi |
HET | Early adult | decreased T cell number | T cell CD3+ percentage FACs Analysis |
HMGU EuroPhenome |
5.00×10-05 | |
| Rnf169 Rnf169tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | T cell CD8+ percentage FACs Analysis |
MRC Harwell EuroPhenome |
5.08×10-05 | |
| Aldh2 Aldh2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased CD4-positive, alpha-beta T cell number | T cell CD4+ percentage FACs Analysis |
MRC Harwell EuroPhenome |
5.16×10-05 | |
| Gpr83 Gpr83em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD4-positive NK T cell number | CD4+ NKT cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
5.99×10-05 | |
| Fam234b Fam234btm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased T cell number | T cell CD3+ percentage FACs Analysis |
HMGU EuroPhenome |
6.07×10-05 | |
| Pknox1 Pknox1Gt(EUCJ0079d10)Hmgu |
HET | Early adult | decreased T cell number | CD25+ percentage of CD4+ T cells FACs Analysis |
HMGU EuroPhenome |
6.13×10-05 | |
| Abcg8 Abcg8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased NK T cell number | NKT cells (panel A) Immunophenotyping |
CCP-IMG IMPC |
6.45×10-05 | |
| Dock10 Dock10tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased T cell number | CD25+ percentage of CD4+ T cells FACs Analysis |
HMGU EuroPhenome |
6.93×10-05 | |
| Gpr83 Gpr83em1(IMPC)Ccpcz |
HOM | Early adult | decreased memory-marker CD4-positive NK T cell number | Effector CD4+ NKT cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
8.28×10-05 | |
| Cimap1b Cimap1bem1(IMPC)Ccpcz |
HOM | Early adult | decreased NK T cell number | NKT cells (panel A) - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
8.36×10-05 | |
| Xbp1 Xbp1tm1a(EUCOMM)Wtsi |
HET | Early adult | decreased T cell number | CD25+ percentage of CD4+ T cells FACs Analysis |
HMGU EuroPhenome |
8.55×10-05 | |
| Pank2 Pank2em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD8-positive, alpha-beta T cell number | CD8+ T cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
8.60×10-05 | |
| Babam1 Babam1em1(IMPC)Ccpcz |
HOM | Early adult | decreased NK T cell number | NKT cells (panel A) - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
9.10×10-05 | |
| Ube3c Ube3ctm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased CD4-negative NK T cell number | DN NKT cells Immunophenotyping |
HMGU IMPC |
9.11×10-05 | |
| Prss57 Prss57em1(IMPC)Ccpcz |
HOM | Early adult | decreased NK T cell number | NKT cells (panel A) - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
9.20×10-05 | |
| Babam1 Babam1em1(IMPC)Ccpcz |
HOM | Early adult | decreased CD4-positive NK T cell number | CD4+ NKT cells - % of live leukocytes (Panel A) Immunophenotyping |
CCP-IMG IMPC |
9.48×10-05 | |
| Mmp11 Mmp11tm1a(EUCOMM)Hmgu |
HET | Early adult | decreased T cell number | CD25+ percentage of CD4+ T cells FACs Analysis |
HMGU EuroPhenome |
9.92×10-05 | |
| Pdia6 Pdia6tm1b(EUCOMM)Hmgu |
HET | Late adult | decreased CD4-positive NK T cell number | CD4 NKT cells Immunophenotyping |
HMGU IMPC |
0.000100 |