Phenotype: increased heart weight

Definition greater than average weight of the heart compared to controls

Related
Synonyms
  • increased heart right ventricle weight
  • increased heart right ventricle weight
  • increased left ventricle weight
  • increased left ventricle weight
  • increased heart right atrium weight
  • increased heart left atrium weight
Show more

MP browserMP:0002833

Login to register interest

Phenotype associations stats

1.72% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased heart weight (67/3904)

1.17% females (45/3855) 1.50% males (58/3875)

Select a parameter    



Gene variants with increased heart weight

Total number of significant genotype-phenotype associations: 103

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Alpk3
Alpk3tm1b(EUCOMM)Hmgu
HOM Female postnatal increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 0.0
Mybpc3
Mybpc3tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 1.17E-19
Slc25a4
Slc25a4tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight WTSI | IMPC 2.44E-19
Ndufs3
Ndufs3tm1a(EUCOMM)Wtsi
HET Male postnatal increased heart weight Heart Dissection | Heart weight WTSI | EuroPhenome 8.31E-13
Gnas
Gnastm1Jop
HOM Female Male postnatal increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 2.14E-11
Sik1
Sik1tm1.1(KOMP)Vlcg
HOM Male postnatal increased heart weight Heart Weight | Heart weight UC Davis | IMPC 3.64E-11
Ric1
Ric1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | MGP 6.73E-11
Grm6
Grm6tm1b(EUCOMM)Wtsi
HOM Female postnatal increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 4.51E-9
Itch
Itchtm1b(EUCOMM)Hmgu
HOM Female postnatal increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 9.41E-9
Rab19
Rab19tm1b(EUCOMM)Hmgu
HOM Male postnatal increased heart weight Heart Weight | Heart weight ICS | IMPC 1.07E-8
Cidec
Cidectm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased heart weight Heart weight/tibia length | Heart weight HMGU | EuroPhenome 5.1E-8
Dynlrb2
Dynlrb2tm1a(KOMP)Wtsi
HET Male postnatal increased heart weight Heart Weight | Heart weight WTSI | IMPC 8.57E-8
Ash1l
Ash1ltm2b(EUCOMM)Hmgu
HET Male postnatal increased heart weight Heart Weight | Heart weight MARC | IMPC 1.17E-7
Lcn2
Lcn2tm1b(KOMP)Wtsi
HOM Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 1.58E-7
Smurf2
Smurf2tm1b(EUCOMM)Wtsi
HET Male postnatal increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 1.59E-7
Asns
Asnstm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | MGP 1.61E-7
Ttc39a
Ttc39atm1b(KOMP)Mbp
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight ICS | IMPC 2.01E-7
Dcp2
Dcp2tm1b(KOMP)Wtsi
HET Female Male postnatal increased heart weight Heart Weight | Heart weight ICS | IMPC 2.12E-7
Srcin1
Srcin1tm1.1(KOMP)Vlcg
HET Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 2.19E-7
Spns1
Spns1tm1e(EUCOMM)Wtsi
HET Male postnatal increased heart weight Heart weight/tibia length | Heart weight ICS | MGP 2.92E-7
2810408A11Rik
2810408A11Riktm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | MGP 3.77E-7
Mpdz
Mpdzem1(IMPC)J
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 5.53E-7
Gpld1
Gpld1tm1.1(KOMP)Vlcg
HOM Male postnatal increased heart weight Heart Weight | Heart weight UC Davis | IMPC 7.34E-7
Dcbld2
Dcbld2tm1a(KOMP)Wtsi
HOM Male postnatal increased heart weight Heart Weight | Heart weight WTSI | IMPC 7.43E-7
Gimap6
Gimap6tm1b(KOMP)Wtsi
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 8.86E-7
Acsl5
Acsl5tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight UC Davis | IMPC 9.13E-7
Exd1
Exd1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight ICS | IMPC 1.01E-6
Mtmr12
Mtmr12tm1b(KOMP)Wtsi
HOM Female postnatal increased heart weight Heart Weight | Heart weight ICS | IMPC 1.08E-6
Adgrf5
Adgrf5tm1b(KOMP)Wtsi
HOM Female postnatal increased heart weight Heart Weight | Heart weight TCP | IMPC 1.27E-6
Lama4
Lama4tm1.1(KOMP)Vlcg
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight UC Davis | IMPC 2.79E-6
Epb41l5
Epb41l5tm1a(EUCOMM)Hmgu
HET Male postnatal increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 3.14E-6
Rimklb
Rimklbtm1.1(KOMP)Vlcg
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 3.2E-6
Rnf10
Rnf10tm1b(KOMP)Wtsi
HET Male postnatal increased heart weight Heart Weight | Heart weight TCP | IMPC 3.8E-6
Pacsin2
Pacsin2tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 5.32E-6
Lrrc15
Lrrc15tm1b(KOMP)Wtsi
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 8.88E-6
Pabpc4
Pabpc4tm1a(KOMP)Wtsi
HOM Male postnatal increased heart weight Heart Weight | Heart weight WTSI | IMPC 9.25E-6
Tead1
Tead1tm1b(KOMP)Wtsi
HET Male postnatal increased heart weight Heart Weight | Heart weight BCM | IMPC 9.84E-6
Romo1
Romo1em1(IMPC)KMPC
HET Female postnatal increased heart weight Heart Weight | Heart weight KMPC | IMPC 1.08E-5
Stx8
Stx8tm2a(EUCOMM)Wtsi
HOM Female postnatal increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 1.35E-5
Lep
Leptm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight BCM | IMPC 1.48E-5
Nos1ap
Nos1aptm1b(KOMP)Wtsi
HOM Male postnatal increased heart weight Heart Weight | Heart weight BCM | IMPC 1.67E-5
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Male postnatal increased heart weight Heart Weight | Heart weight KMPC | IMPC 1.76E-5
Ide
Idetm1a(EUCOMM)Wtsi
HOM Male postnatal increased heart weight Heart Dissection | Heart weight WTSI | EuroPhenome 1.79E-5
Pink1
Pink1tm1b(EUCOMM)Wtsi
HOM Male postnatal increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.01E-5
Rcc2
Rcc2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 2.07E-5
Rab36
Rab36tm1b(KOMP)Wtsi
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 2.15E-5
Rpa1
Rpa1tm1b(KOMP)Wtsi
HET Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 2.15E-5
Tnfaip1
Tnfaip1tm1a(EUCOMM)Wtsi
HOM Male postnatal increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 2.46E-5
Tmem255b
Tmem255btm1a(EUCOMM)Hmgu
HOM Female Male postnatal increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | MGP 2.56E-5
Fbxo43
Fbxo43em1(IMPC)Marc
HOM Male postnatal increased heart weight Heart Weight | Heart weight MARC | IMPC 2.62E-5
Gsto2
Gsto2tm2a(KOMP)Wtsi
HOM Male postnatal increased heart weight Heart Weight | Heart weight WTSI | IMPC 3.15E-5
Sparc
Sparctm1a(EUCOMM)Wtsi
HOM Female postnatal increased heart weight Heart weight/tibia length | Heart weight WTSI | EuroPhenome 3.3E-5
Elk4
Elk4tm1a(EUCOMM)Wtsi
HOM Female Male postnatal increased heart weight Heart weight/tibia length | Heart weight HMGU | EuroPhenome 4.49E-5
Dppa1
Dppa1tm1a(KOMP)Wtsi
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight WTSI | IMPC 4.61E-5
Nptn
Nptntm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 4.97E-5
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight TCP | IMPC 4.98E-5
H2-M5
H2-M5tm1(KOMP)Wtsi
HOM Female Male postnatal increased heart weight Heart Dissection | Heart weight WTSI | MGP 5.3E-5
Col1a2
Col1a2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight BCM | IMPC 5.45E-5
Xylb
Xylbtm1a(EUCOMM)Hmgu
HOM Male postnatal increased heart weight Heart weight/tibia length | Heart weight MRC Harwell | EuroPhenome 6.26E-5
Ptpn5
Ptpn5tm1b(KOMP)Wtsi
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 6.43E-5
Gorasp1
Gorasp1tm1b(KOMP)Wtsi
HET Female Male postnatal increased heart weight Heart Weight | Heart weight ICS | IMPC 7.03E-5
Myh1
Myh1tm1b(KOMP)Wtsi
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 7.49E-5
Nalcn
Nalcnem1(IMPC)Mbp
HET Female Male postnatal increased heart weight Heart Weight | Heart weight UC Davis | IMPC 8.35E-5
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Female Male postnatal increased heart weight Organ Weight | Heart weight MRC Harwell | IMPC 8.79E-5
Galnt12
Galnt12em1(IMPC)J
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 8.85E-5
Ttll10
Ttll10em1(IMPC)J
HOM Female Male postnatal increased heart weight Heart Weight | Heart weight JAX | IMPC 9.11E-5
Phex
Phexnot yet available
HOM Female postnatal increased heart weight Heart weight/tibia length | Heart weight HMGU | EuroPhenome 9.56E-5

Download data as: TSV XLS