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Phenotype: increased IgG level

Definition
greater than normal immunoglobulin class G level
Synonyms
hypergammaglobulinemia
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased IgG level

Total number of significant genotype-phenotype associations: 16

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Plcg2
Plcg2Ali14 		HET Early adult increased IgG1 level IgG1
Immunoglobulin		 HMGU
EuroPhenome		 3.25×10-15
Clk1
Clk1tm1a(EUCOMM)Wtsi 		HOM Early adult increased IgG2b level IgG2b
Immunoglobulin		 ICS
EuroPhenome		 1.43×10-08
Mysm1
Mysm1tm1a(KOMP)Wtsi 		HOM Early adult increased IgG2b level IgG2b
Immunoglobulin		 HMGU
EuroPhenome		 2.91×10-08
Nfya
NfyaGt(EUCJ0004f10)Hmgu 		HET Early adult increased IgG1 level IgG1
Immunoglobulin		 HMGU
EuroPhenome		 2.05×10-07
Gper1
Gper1tm1Dgen 		HOM Early adult increased IgG2b level IgG2b
Immunoglobulin		 HMGU
EuroPhenome		 2.78×10-07
Usp12
Usp12tm1a(EUCOMM)Hmgu 		HOM Early adult increased IgG3 level IgG3
Immunoglobulin		 HMGU
EuroPhenome		 2.85×10-07
Bspry
Bsprytm1a(EUCOMM)Wtsi 		HOM Early adult increased IgG1 level IgG1
Immunoglobulin		 ICS
EuroPhenome		 1.90×10-06
Aldh2
Aldh2tm1a(EUCOMM)Wtsi 		HOM Early adult increased IgG1 level IgG1
Immunoglobulin		 HMGU
EuroPhenome		 2.27×10-06
Plcg2
Plcg2Ali14 		HET Early adult increased IgG2b level IgG2b
Immunoglobulin		 HMGU
EuroPhenome		 2.48×10-06
Vmp1
Vmp1not yet available 		HET Early adult increased IgG2b level IgG2b
Immunoglobulin		 HMGU
EuroPhenome		 4.97×10-06
Bspry
Bsprytm1a(EUCOMM)Wtsi 		HOM   Early adult increased IgG2b level IgG2b
Immunoglobulin		 ICS
EuroPhenome		 7.70×10-06
Mysm1
Mysm1tm1a(KOMP)Wtsi 		HOM Early adult increased IgG3 level IgG3
Immunoglobulin		 HMGU
EuroPhenome		 1.09×10-05
Xiap
Xiaptm1a(EUCOMM)Hmgu 		HOM Early adult increased IgG1 level IgG1
Immunoglobulin		 ICS
EuroPhenome		 2.19×10-05
Rere
RereRere 		HET Early adult increased IgG2b level IgG2b
Immunoglobulin		 ICS
EuroPhenome		 2.47×10-05
Crtc1
Crtc1tm1a(EUCOMM)Wtsi 		HET Early adult increased IgG2b level IgG2b
Immunoglobulin		 ICS
EuroPhenome		 4.09×10-05
Rere
RereRere 		HET Early adult increased IgG1 level IgG1
Immunoglobulin		 ICS
EuroPhenome		 8.39×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Antigen Specific Immunoglobulin Assay
Immunoglobulin
Immunoglobulin concentration
Trichuris

 Phenotype associations stats

10.71% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased IgG level (12/112)

5.74% females (7/122) 5.04% males (6/119)

Select a parameter    



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