Phenotype: abnormal liver morphology

Definition any structural anomaly of the bile-secreting organ that is important for detoxification, for fat, carbohydrate, and protein metabolism, and for glycogen storage

Synonyms
  • liver dysplasia
  • liver dysplasia
  • abnormal hepatic morphology
  • abnormal hepatic morphology
  • abnormal liver
Show more
Related
Synonyms
  • Copper accumulation in liver
  • Copper accumulation in liver
  • Elevated hepatic iron concentration
  • Elevated hepatic iron concentration
  • Increased hepatic glycogen content
  • Increased iron concentration in liver
  • Increased liver glycogen content
  • Increased liver iron level
  • Intrahepatic atresia of biliary duct
  • Intrahepatic bile duct cysts
  • Intrahepatic biliary atresia
  • Liver copper accumulation
  • abnormal biliary ductule morphology
  • abnormal canal of Hering
  • abnormal cannalicular ductule morphology
  • abnormal classic lobule
  • abnormal classical lobule
  • abnormal ductuli biliferi
  • abnormal hepatic cholesterol level
  • abnormal hepatic copper content
  • abnormal hepatic cord morphology
  • abnormal hepatic glycogen level
  • abnormal hepatic iron level
  • abnormal hepatic iron load
  • abnormal hepatic lamina morphology
  • abnormal hepatic laminae
  • abnormal hepatic lobule morphology
  • abnormal hepatic parenchyma morphology
  • abnormal hepatic regeneration
  • abnormal hepatic sinusoid morphology
  • abnormal hepatic triglyceride level
  • abnormal hepatic vasculature morphology
  • abnormal hepatic vein morphology
  • abnormal interlobular bile duct morphology
  • abnormal interlobular ductule morphology
  • abnormal intrahepatic bile duct morphology
  • abnormal intrahepatic bile ductule morphology
  • abnormal intrahepatic biliary system morphology
  • abnormal intralobular bile duct morphology
  • abnormal lamina hepatica morphology
  • abnormal liver cell plate morphology
  • abnormal liver cholesterol level
  • abnormal liver copper concentration
  • abnormal liver copper level
  • abnormal liver glycogen level
  • abnormal liver iron level
  • abnormal liver iron load
  • abnormal liver lobule morphology
  • abnormal liver parenchyma morphology
  • abnormal liver regeneration
  • abnormal liver sinusoid morphology
  • abnormal liver triglyceride level
  • abnormal liver vasculature morphology
  • abnormal liver zinc level
  • abnormal portal lobule morphology
  • congested liver vasculature
  • decreased hepatic cholesterol level
  • decreased hepatic copper content
  • decreased hepatic free fatty acids level
  • decreased hepatic glycogen level
  • decreased hepatic iron level
  • decreased hepatic iron load
  • decreased hepatic regeneration
  • decreased hepatic triglyceride level
  • decreased liver cholesterol level
  • decreased liver copper level
  • decreased liver free fatty acids level
  • decreased liver glycogen level
  • decreased liver iron level
  • decreased liver iron load
  • decreased liver regeneration
  • decreased liver triglyceride level
  • decreased susceptibility to fatty liver development
  • decreased susceptibility to hepatic steatosis
  • diffuse hepatic necrosis
  • diffuse liver necrosis
  • enhanced liver regeneration
  • fatty liver
  • focal hepatic necrosis
  • focal liver necrosis
  • hepatic arteriovenous fistula
  • hepatic arteriovenous malformation
  • hepatic cysts
  • hepatic degeneration
  • hepatic herniation
  • hepatic lipidosis
  • hepatic necrosis
  • hepatic peliosis
  • hepatic peliotic cavities
  • hepatic steatosis
  • hepatic vascular congestion
  • hepatic vasculature dysplasia
  • hepatosteatosis
  • herniated liver
  • increased hepatic cholesterol level
  • increased hepatic copper content
  • increased hepatic free fatty acids level
  • increased hepatic glycogen level
  • increased hepatic iron level
  • increased hepatic iron load
  • increased hepatic regeneration
  • increased hepatic triglyceride level
  • increased liver cholesterol level
  • increased liver copper level
  • increased liver free fatty acids level
  • increased liver glycogen level
  • increased liver iron level
  • increased liver iron load
  • increased liver regeneration
  • increased liver triglyceride level
  • increased resistance to fatty liver development
  • increased resistance to hepatic steatosis
  • liver adiposis
  • liver arteriovenous fisutla
  • liver arteriovenous malformation
  • liver cysts
  • liver degeneration
  • liver hemorrhage
  • liver hernia
  • liver iron deposits
  • liver necrosis
  • liver peliosis
  • liver steatosis
  • liver vascular congestion
  • liver vasculature dysplasia
  • multifocal hepatic necrosis
  • multifocal liver necrosis
  • reduced hepatic cholesterol level
  • reduced hepatic copper content
  • reduced hepatic free fatty acids level
  • reduced hepatic glycogen level
  • reduced hepatic iron level
  • reduced hepatic regeneration
  • reduced hepatic triglyceride level
  • reduced liver cholesterol level
  • reduced liver copper level
  • reduced liver free fatty acids level
  • reduced liver glycogen level
  • reduced liver iron level
  • reduced liver regeneration
  • reduced liver triglyceride level
Show more

MP browserMP:0000598

Login to register interest

Phenotype associations stats

1.51% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal liver morphology (36/2377)

0.72% females (17/2366) 1.15% males (27/2357)

Gene variants with abnormal liver morphology

Total number of significant genotype-phenotype associations: 48

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Adnp2
Adnp2em1Tcp
HOM Female postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver TCP | IMPC 0.0
Aif1l
Aif1ltm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver BCM | IMPC 0.0
Akap10
Akap10tm1.1(KOMP)Vlcg
HET Male embryonic day 12.5 abnormal liver size Gross Morphology Embryo E12.5 | Liver Size TCP | IMPC 0.0
Bcl2l12
Bcl2l12tm1.1(KOMP)Vlcg
HOM Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver UC Davis | IMPC 0.0
Bloc1s2
Bloc1s2tm1.1(KOMP)Mbp
HOM Male embryonic day 12.5 pale liver Gross Morphology Embryo E12.5 | Pale Liver JAX | IMPC 0.0
Cacna1i
Cacna1itm1b(KOMP)Wtsi
HOM Female postnatal small liver Gross Pathology and Tissue Collection | Liver BCM | IMPC 0.0
Ccdc124
Ccdc124tm1b(KOMP)Wtsi
HOM Female Male postnatal small liver Gross Pathology and Tissue Collection | Liver MARC | IMPC 0.0
Cox5b
Cox5btm2b(EUCOMM)Hmgu
HOM Male embryonic day 12.5 abnormal liver size Gross Morphology Embryo E12.5 | Liver Size BCM | IMPC 0.0
Cox5b
Cox5btm2b(EUCOMM)Hmgu
HOM Male embryonic day 12.5 pale liver Gross Morphology Embryo E12.5 | Pale Liver BCM | IMPC 0.0
Cpe
Cpetm1b(EUCOMM)Hmgu
HOM Female Male postnatal enlarged liver Gross Pathology and Tissue Collection | Liver HMGU | IMPC 0.0
Dagla
Daglatm1a(EUCOMM)Wtsi
HOM Male postnatal small liver Gross Pathology and Tissue Collection | Liver MARC | IMPC 0.0
Emb
Embtm1b(KOMP)Wtsi
HET Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver UC Davis | IMPC 0.0
Fbxo38
Fbxo38em2Marc
HOM Female postnatal small liver Gross Pathology and Tissue Collection | Liver MARC | IMPC 0.0
Fstl3
Fstl3tm1.1(KOMP)Vlcg
HOM Female postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver UC Davis | IMPC 0.0
Gjb4
Gjb4tm1.1(KOMP)Vlcg
HOM Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver UC Davis | IMPC 0.0
Gprc5b
Gprc5btm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver UC Davis | IMPC 0.0
Gps1
Gps1tm1b(KOMP)Wtsi
HET Female Male embryonic day 12.5 abnormal liver size Gross Morphology Embryo E12.5 | Liver Size TCP | IMPC 0.0
Hddc3
Hddc3tm1.1(KOMP)Vlcg
HOM Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver UC Davis | IMPC 0.0
Hectd3
Hectd3tm1(NCOM)Cmhd
HOM Female Male postnatal small liver Gross Pathology and Tissue Collection | Liver MARC | IMPC 0.0
Kdm1a
Kdm1atm1(NCOM)Mfgc
HET Female postnatal small liver Gross Pathology and Tissue Collection | Liver MARC | IMPC 0.0
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Female Male postnatal enlarged liver Gross Pathology and Tissue Collection | Liver MRC Harwell | IMPC 0.0
Lhcgr
Lhcgrtm1(KOMP)Vlcg
HOM Male postnatal small liver Gross Pathology and Tissue Collection | Liver MARC | IMPC 0.0
Med16
Med16tm1b(KOMP)Wtsi
HOM Male embryonic day 12.5 pale liver Gross Morphology Embryo E12.5 | Pale Liver TCP | IMPC 0.0
Myo18a
Myo18atm1b(KOMP)Wtsi
HOM Female Male embryonic day 12.5 pale liver Gross Morphology Embryo E12.5 | Pale Liver TCP | IMPC 0.0
Nab2
Nab2tm1b(EUCOMM)Hmgu
HOM Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver ICS | IMPC 0.0
Pstpip2
Pstpip2em2Tcp
HOM Female postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver TCP | IMPC 0.0
Rxfp2
Rxfp2tm1b(EUCOMM)Wtsi
HOM Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver HMGU | IMPC 0.0
Sec24d
Sec24dem1Rbrc
HET Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver RBRC | IMPC 0.0
St14
St14tm1.1(KOMP)Vlcg
HOM Female Male embryonic day 12.5 abnormal liver size Gross Morphology Embryo E12.5 | Liver Size TCP | IMPC 0.0
St14
St14tm1.1(KOMP)Vlcg
HOM Female Male embryonic day 12.5 pale liver Gross Morphology Embryo E12.5 | Pale Liver TCP | IMPC 0.0
Sufu
Sufutm1b(KOMP)Wtsi
HOM Male embryonic day 12.5 abnormal liver size Gross Morphology Embryo E12.5 | Liver Size TCP | IMPC 0.0
Sufu
Sufutm1b(KOMP)Wtsi
HOM Male embryonic day 12.5 pale liver Gross Morphology Embryo E12.5 | Pale Liver TCP | IMPC 0.0
Supt4a
Supt4atm1b(EUCOMM)Hmgu
HET Female embryonic day 12.5 pale liver Gross Morphology Embryo E12.5 | Pale Liver TCP | IMPC 0.0
Thbs1
Thbs1tm1.1(KOMP)Vlcg
HOM Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver UC Davis | IMPC 0.0
Trmt1
Trmt1tm1b(EUCOMM)Hmgu
HET Female postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver ICS | IMPC 0.0
Ube2g1
Ube2g1tm1b(EUCOMM)Hmgu
HOM Male postnatal small liver Gross Pathology and Tissue Collection | Liver RBRC | IMPC 0.0
Ubr2
Ubr2tm1e.1(KOMP)Mbp
HET Female postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver UC Davis | IMPC 0.0
Unc119
Unc119tm1.1(KOMP)Vlcg
HOM Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver UC Davis | IMPC 0.0
Zc3hav1l
Zc3hav1ltm1b(EUCOMM)Wtsi
HOM Female Male postnatal abnormal liver morphology Gross Pathology and Tissue Collection | Liver UC Davis | IMPC 0.0

Download data as: TSV XLS