Phenotype: thin ventricular wall

Definition decreased depth of the cardiac wall of the heart ventricles

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Phenotype associations stats

2.53% of tested genes with null mutations on a B6N genetic background have a phenotype association to thin ventricular wall (28/1108)

2.36% females (26/1100) 2.87% males (24/835)

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Gene variants with thin ventricular wall

Total number of significant genotype-phenotype associations: 54

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Pcx
Pcxtm1b(EUCOMM)Wtsi
HET Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 1.39E-29
Map3k10
Map3k10tm1b(EUCOMM)Hmgu
HOM Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 5.08E-19
Dbn1
Dbn1tm1b(KOMP)Wtsi
HET Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 5.05E-9
Entpd1
Entpd1tm1b(EUCOMM)Wtsi
HOM Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 7.34E-9
Dnajc17
Dnajc17tm1b(EUCOMM)Hmgu
HET Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 9.76E-9
Ints6l
Ints6lem1Marc
HEM Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 1.77E-8
Fyb
Fybtm1b(EUCOMM)Hmgu
HOM Female postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 4.08E-8
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 4.22E-8
Abcb11
Abcb11tm1b(EUCOMM)Hmgu
HET Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 1.77E-7
Abcb11
Abcb11tm1b(EUCOMM)Hmgu
HOM Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 1.77E-7
Phf21b
Phf21bem1Marc
HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 9.88E-7
Nr1d1
Nr1d1tm1(KOMP)Vlcg
HOM Female Male postnatal thin ventricular wall Echo | LVAWs BCM | IMPC 1.98E-6
Esr2
Esr2em1Marc
HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 2.85E-6
Lsm1
Lsm1tm1b(EUCOMM)Hmgu
HET Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 3.87E-6
Hilpda
Hilpdaem1Mhzh
HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 4.19E-6
Wfdc11
Wfdc11em1Marc
HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 5.12E-6
Pfkfb2
Pfkfb2tm1b(KOMP)Wtsi
HOM Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 6.63E-6
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
HET Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 9.02E-6
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 9.02E-6
Rest
Resttm2b(EUCOMM)Wtsi
HET Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 1.93E-5
Trim37
Trim37em1Marc
HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 2.34E-5
Usp26
Usp26em1Marc
HOM Female postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 2.98E-5
Ints6l
Ints6lem1Marc
HOM Female postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 3.3E-5
Ccdc83
Ccdc83em1Marc
HOM Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 3.46E-5
Defb43
Defb43tm1b(KOMP)Wtsi
HOM Female postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 3.51E-5
Vav2
Vav2em1Marc
HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 4.01E-5
Gad2
Gad2tm1b(EUCOMM)Wtsi
HOM Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 4.15E-5
Fam216a
Fam216atm1b(EUCOMM)Hmgu
HOM Female Male postnatal thin ventricular wall Echo | LVPWd HMGU | IMPC 4.16E-5
Acsm1
Acsm1em1Mhzh
HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 4.78E-5
Ins1
Ins1em1Marc
HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 7.1E-5
Emc10
Emc10tm1b(EUCOMM)Wtsi
HOM Female postnatal thin ventricular wall Echo | LVPWd MRC Harwell | IMPC 7.34E-5

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