Phenotype: thin ventricular wall

Definition decreased depth of the cardiac wall of the heart ventricles

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Phenotype associations stats

1.26% of tested genes with null mutations on a B6N genetic background have a phenotype association to thin ventricular wall (15/1195)

1.18% females (14/1182) 1.31% males (12/913)

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Gene variants with thin ventricular wall

Total number of significant genotype-phenotype associations: 26

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Ints6l
Ints6lem1(IMPC)Marc
HEM Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 2.4E-9
Phf21b
Phf21bem1(IMPC)Marc
HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 9.88E-7
Nr1d1
Nr1d1tm1(KOMP)Vlcg
HOM Female Male postnatal thin ventricular wall Echo | LVAWs BCM | IMPC 2.6E-6
Wfdc11
Wfdc11em1(IMPC)Marc
HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 2.77E-6
Defb43
Defb43tm1b(KOMP)Wtsi
HOM Female postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 2.89E-6
Esr2
Esr2em1(IMPC)Marc
HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 5.75E-6
Fbxo22
Fbxo22tm1b(EUCOMM)Wtsi
HET Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 7.39E-6
Hilpda
Hilpdaem1(IMPC)Mhzh
HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 9.52E-6
Ints6l
Ints6lem1(IMPC)Marc
HOM Female postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 3.6E-5
Ins1
Ins1em1(IMPC)Marc
HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 4.29E-5
Acsm1
Acsm1em1(IMPC)Mhzh
HOM Female Male postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 6.91E-5
Vav2
Vav2em1(IMPC)Marc
HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 7.01E-5
Emc10
Emc10tm1b(EUCOMM)Wtsi
HOM Female postnatal thin ventricular wall Echo | LVPWd MRC Harwell | IMPC 8.66E-5
Ccdc83
Ccdc83em1(IMPC)Marc
HOM Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 8.91E-5
Trim37
Trim37em1(IMPC)Marc
HOM Female Male postnatal thin ventricular wall Echo | LVPWd MARC | IMPC 8.98E-5
Usp26
Usp26em1(IMPC)Marc
HOM Female postnatal thin ventricular wall Echo | LVAWs MARC | IMPC 9.26E-5

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