Definition
forward curvature of the spine, characterized by extensive flexion
Synonyms
humpback,
hunchback
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with kyphosis
Total number of significant genotype-phenotype associations: 24
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | kyphosis | Kyphosis X-ray |
WTSI IMPC |
2.71×10-10 | |
| Slc20a2 Slc20a2tm1a(EUCOMM)Wtsi |
HOM | Early adult | kyphosis | Kyphosis X-ray |
WTSI IMPC |
5.58×10-08 | |
| Fgf14 Fgf14em1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
2.11×10-07 | |
| Cer1 Cer1em1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
3.05×10-07 | |
| Calb1 Calb1em1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
2.35×10-06 | |
| Mfng Mfngem1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
2.35×10-06 | |
| Tram2 Tram2tm1a(KOMP)Wtsi |
HOM | Early adult | kyphosis | Kyphosis X-ray |
WTSI IMPC |
2.92×10-06 | |
| Bbip1 Bbip1em1(IMPC)Ccpcz |
HET | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
3.11×10-06 | |
| Bmp6 Bmp6em1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
3.11×10-06 | |
| Ak7 Ak7em1(IMPC)Ccpcz |
HET | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
3.90×10-06 | |
| Ropn1l Ropn1ltm1b(EUCOMM)Wtsi |
HOM | Early adult | kyphosis | Kyphosis X-ray |
WTSI IMPC |
7.53×10-06 | |
| Wdr37 Wdr37tm1a(KOMP)Wtsi |
HOM | Early adult | kyphosis | Kyphosis X-ray |
WTSI IMPC |
7.53×10-06 | |
| Prss54 Prss54em1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
9.72×10-06 | |
| Zc2hc1c Zc2hc1cem1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
1.16×10-05 | |
| Prss21 Prss21em1(IMPC)Ccpcz |
HET | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
1.43×10-05 | |
| Tpte Tpteem1(IMPC)Kmpc |
HOM | Early adult | kyphosis | Kyphosis X-ray |
KMPC IMPC |
1.51×10-05 | |
| Kcnv2 Kcnv2tm1Wtsi |
HOM | Early adult | kyphosis | Kyphosis X-ray |
WTSI IMPC |
1.79×10-05 | |
| Krt72 Krt72em1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
2.05×10-05 | |
| Rnf148 Rnf148em1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
2.05×10-05 | |
| Fam221a Fam221aem1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
3.04×10-05 | |
| Prss35 Prss35em1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
3.71×10-05 | |
| Arg2 Arg2em1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
7.66×10-05 | |
| Klhl1 Klhl1em1(IMPC)Ccpcz |
HOM | Early adult | kyphosis | Kyphosis X-ray |
CCP-IMG IMPC |
7.66×10-05 |