Eye Morphology: Images Ophthalmoscopy

WT Images

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: LEFT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia ; LEFT EYE: A little bit of Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia; LEFT EYE: Slight opacity on lens, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Severe Rd8; LEFT EYE: Slight lens opacity, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

Mutant Images

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present. ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present.

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; RIGHT EYE: Crystallized debris.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; LEFT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left); LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left)

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; RIGHT EYE: Crystallized debris.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; LEFT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia ; LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left); LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left)

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; LEFT EYE: Tiny crystallized debris, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia ; LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left); LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left)

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia ; LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present ; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia ; LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia ; LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some debris (difficult to focus). Severe rd8; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present ; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia ; LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), some dysplasia,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left); LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left)

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left); LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left)

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left); LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity. Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE: Some lens opacity/debris (difficult to focus). Blood vessel early branching (mid left)

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present ; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; LEFT EYE: Tiny crystallized debris, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small debris,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Some lens opacity (difficult to image and focus).

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present ; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; LEFT EYE: Tiny crystallized debris, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; LEFT EYE: Tiny crystallized debris, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; LEFT EYE: Tiny crystallized debris, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present ; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present. ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present.

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; RIGHT EYE: Crystallized debris.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; LEFT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present. ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present.

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; LEFT EYE: Tiny crystallized debris, small lesion,
Ophthalmoscope Observation: Both eyes slight lens opacity, severe rd8 ; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present. ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present.

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, moderate rd8, moderate dysplasia; RIGHT EYE: Crystallized debris

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; LEFT EYE: Severe rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity; RIGHT EYE: Hyaloid present, slight corneal opacity, severe dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8 ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; LEFT EYE: Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity ; RIGHT EYE: Severe rd8

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; RIGHT EYE: Crystallized debris.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; LEFT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present. ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present.

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8.; RIGHT EYE: Tiny hyaloid present. Blood vessel slightly early branching

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; RIGHT EYE: Crystallized debris.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; LEFT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; LEFT EYE: Small hyaloid and crystallized debris present. Some rd8, slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes slight dysplasia and lens opacity (difficult to focus).; RIGHT EYE: Some debris.

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present. ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present.

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present ; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; LEFT EYE: Small cataract, some corneal opacity (difficult to focus). Blood vessel slightly early branching,
Ophthalmoscope Observation: Both eyes some dysplasia, slight hemorrhage; RIGHT EYE: Some lens opacity, small lesion present

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; LEFT EYE: Crystallized debris. Blood vessel early branching. Moderate rd8,
Ophthalmoscope Observation: Both eyes slight lens opacity, some dysplasia; RIGHT EYE: Blood vessel slightly early branching. Some rd8

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; RIGHT EYE: Slight hemorrhaging,
Ophthalmoscope Observation: Both eyes slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE: Some lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE: Slight lens opacity, some dysplasia

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; RIGHT EYE: Crystallized debris.,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight rd8 ; LEFT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia; LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus), severe rd8,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity, moderate rd8, slight dysplasia

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present. ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity (difficult to focus).; RIGHT EYE: Hyaloid present.

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; LEFT EYE: Some lens opacity, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some dysplasia; RIGHT EYE: Slight lens opacity

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; LEFT EYE: Very slight rd8.,
Ophthalmoscope Observation: Both eyes slight dysplasia and opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; LEFT EYE: Small hyaloid present,
Ophthalmoscope Observation: Both eyes some rd8 and lens opacity/debris (difficult to focus). Blood vessel early branching; RIGHT EYE:

57 weeks old

Phrf1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging ; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; LEFT EYE: Blood vessel early branching,
Ophthalmoscope Observation: Both eyes slight lens opacity. Slight dysplasia.; RIGHT EYE: Some rd8 and slight hemorrhaging

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter