Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity, difficult to focus. Some dysplasia; LEFT EYE: Slight lens opacity. Early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight dysplasia, very slight molten patches; LEFT EYE: Some lens opacity, Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Crystallized debris, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8 ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Crystallized debris, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging ; RIGHT EYE: Early blood vessel branching; LEFT EYE: Slightly early blood vessel branching, uneven blood vessels thickness,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia; RIGHT EYE: Hyaloid present ; LEFT EYE: Crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia. ; LEFT EYE: Small hyaloid, small crystallized debris, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia.

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Early blood vessel branching, slight hemorhaging.and some lens opacity.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Some crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging ; RIGHT EYE: Early blood vessel branching; LEFT EYE: Slightly early blood vessel branching, uneven blood vessels thickness,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight dysplasia, very slight molten patches; LEFT EYE: Some lens opacity, Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Early blood vessel branching, slight hemorhaging.and some lens opacity.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity, difficult to focus. Some dysplasia; LEFT EYE: Slight lens opacity. Early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Some crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity, difficult to focus. Some dysplasia; LEFT EYE: Slight lens opacity. Early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, crystallized debris; RIGHT EYE: Corneal opacity, some lens opacity, early blood vessel branching, slight hemorrhage, slight dysplasia; LEFT EYE: Hyaloid present, slight lens opacity, slightly early blod vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, crystallized debris

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching ; RIGHT EYE: Some dysplasia ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Early blood vessel branching, slight hemorhaging.and some lens opacity.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging; RIGHT EYE: Early vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, crystallized debris; RIGHT EYE: Corneal opacity, some lens opacity, early blood vessel branching, slight hemorrhage, slight dysplasia; LEFT EYE: Hyaloid present, slight lens opacity, slightly early blod vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, crystallized debris

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some dysplasia, very slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8 ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight dysplasia, very slight molten patches; LEFT EYE: Some lens opacity, Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Early blood vessel branching, slight hemorhaging.and some lens opacity.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching. ; RIGHT EYE: Slight lens opacity, some dysplasia, crystallized debris ; LEFT EYE: Some lens opacity (difficult to focus), slight dysplasia, slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching.

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia. ; LEFT EYE: Small hyaloid, small crystallized debris, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia.

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, crystallized debris; RIGHT EYE: Corneal opacity, some lens opacity, early blood vessel branching, slight hemorrhage, slight dysplasia; LEFT EYE: Hyaloid present, slight lens opacity, slightly early blod vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, crystallized debris

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching. ; RIGHT EYE: Slight lens opacity, some dysplasia, crystallized debris ; LEFT EYE: Some lens opacity (difficult to focus), slight dysplasia, slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching.

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Crystallized debris, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia ; LEFT EYE: Small hyaloid, crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging; RIGHT EYE: Early vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching. ; RIGHT EYE: Slight lens opacity, some dysplasia, crystallized debris ; LEFT EYE: Some lens opacity (difficult to focus), slight dysplasia, slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching.

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Early blood vessel branching, slight hemorhaging.and some lens opacity.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging; RIGHT EYE: Early vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight dysplasia, very slight molten patches; LEFT EYE: Some lens opacity, Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity, difficult to focus. Some dysplasia; LEFT EYE: Slight lens opacity. Early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Crystallized debris, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Some crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, crystallized debris; RIGHT EYE: Corneal opacity, some lens opacity, early blood vessel branching, slight hemorrhage, slight dysplasia; LEFT EYE: Hyaloid present, slight lens opacity, slightly early blod vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, crystallized debris

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some dysplasia, very slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia. ; LEFT EYE: Small hyaloid, small crystallized debris, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia.

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity, difficult to focus. Some dysplasia; LEFT EYE: Slight lens opacity. Early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging ; RIGHT EYE: Early blood vessel branching; LEFT EYE: Slightly early blood vessel branching, uneven blood vessels thickness,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia ; LEFT EYE: Small hyaloid, crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Crystallized debris, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8 ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Some lens opacity, difficult to focus. Some dysplasia; LEFT EYE: Slight lens opacity. Early blood vessel branching, slight dysplasia,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some dysplasia, very slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching. ; RIGHT EYE: Slight lens opacity, some dysplasia, crystallized debris ; LEFT EYE: Some lens opacity (difficult to focus), slight dysplasia, slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching.

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia. ; LEFT EYE: Small hyaloid, small crystallized debris, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia.

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging ; RIGHT EYE: Early blood vessel branching; LEFT EYE: Slightly early blood vessel branching, uneven blood vessels thickness,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia; RIGHT EYE: Hyaloid present ; LEFT EYE: Crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Some crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching. ; RIGHT EYE: Slight lens opacity, some dysplasia, crystallized debris ; LEFT EYE: Some lens opacity (difficult to focus), slight dysplasia, slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching.

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia; RIGHT EYE: Hyaloid present ; LEFT EYE: Crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Crystallized debris, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia ; LEFT EYE: Small hyaloid, crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging; RIGHT EYE: Early vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia; RIGHT EYE: Hyaloid present ; LEFT EYE: Crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, crystallized debris; RIGHT EYE: Corneal opacity, some lens opacity, early blood vessel branching, slight hemorrhage, slight dysplasia; LEFT EYE: Hyaloid present, slight lens opacity, slightly early blod vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, crystallized debris

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia; RIGHT EYE: Hyaloid present ; LEFT EYE: Crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging; RIGHT EYE: Early vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8 ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching ; RIGHT EYE: Some dysplasia ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Some crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Crystallized debris, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia ; LEFT EYE: Small hyaloid, crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia ; LEFT EYE: Small hyaloid, crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging ; RIGHT EYE: Early blood vessel branching; LEFT EYE: Slightly early blood vessel branching, uneven blood vessels thickness,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching ; RIGHT EYE: Some dysplasia ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some dysplasia, very slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia ; LEFT EYE: Small hyaloid, crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Crystallized debris, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes hyaloid present, slight lens opacity, some rd8, some dysplasia, slight hemorrhage

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia; RIGHT EYE: Hyaloid present ; LEFT EYE: Crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia. ; LEFT EYE: Small hyaloid, small crystallized debris, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia.

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight dysplasia, very slight molten patches; LEFT EYE: Some lens opacity, Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia. ; LEFT EYE: Small hyaloid, small crystallized debris, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia.

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, crystallized debris; RIGHT EYE: Corneal opacity, some lens opacity, early blood vessel branching, slight hemorrhage, slight dysplasia; LEFT EYE: Hyaloid present, slight lens opacity, slightly early blod vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, crystallized debris

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching ; RIGHT EYE: Some dysplasia ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some dysplasia, very slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging; RIGHT EYE: Early vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, molten patches, slight dysplasia, some rd8 and slight hemorrhaging

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia; RIGHT EYE: Early blood vessel branching, slight hemorhaging.and some lens opacity.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching ; RIGHT EYE: Some dysplasia ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8 ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Slight lens opacity, slight dysplasia, very slight molten patches; LEFT EYE: Some lens opacity, Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching ; RIGHT EYE: Some dysplasia ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhaging, early blood vessel branching

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging ; RIGHT EYE: Early blood vessel branching; LEFT EYE: Slightly early blood vessel branching, uneven blood vessels thickness,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, slight dysplasia, slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia. ; LEFT EYE: Small hyaloid, small crystallized debris, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia.

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 ; RIGHT EYE: Some dysplasia, very slight hemorrhage ; LEFT EYE: Slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8 ; RIGHT EYE: Some lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, some dysplasia, slight hemorrhage, slightly early blood vessel branching,
Ophthalmoscope Observation: Seizure post anti sedan injection. Both eyes some rd8

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, crystallized debris; RIGHT EYE: Corneal opacity, some lens opacity, early blood vessel branching, slight hemorrhage, slight dysplasia; LEFT EYE: Hyaloid present, slight lens opacity, slightly early blod vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, crystallized debris

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching. ; RIGHT EYE: Slight lens opacity, some dysplasia, crystallized debris ; LEFT EYE: Some lens opacity (difficult to focus), slight dysplasia, slight hemorrhaging,
Ophthalmoscope Observation: Both eyes some rd8, slightly early blood vessel branching.

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage ; RIGHT EYE: Some crystallized debris,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some dysplasia, slight hemorrhage

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging; RIGHT EYE: Early blood vessel branching ; LEFT EYE: Slightly early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia, slight hemorrhaging

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, crystallized debris; RIGHT EYE: Corneal opacity, some lens opacity, early blood vessel branching, slight hemorrhage, slight dysplasia; LEFT EYE: Hyaloid present, slight lens opacity, slightly early blod vessel branching,
Ophthalmoscope Observation: Both eyes some rd8, crystallized debris

14 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia; RIGHT EYE: Hyaloid present ; LEFT EYE: Crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight molten patches, some rd8, some dysplasia

15 weeks old

Nosipem1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia ; LEFT EYE: Small hyaloid, crystallized debris, early blood vessel branching,
Ophthalmoscope Observation: Both eyes some lens opacity, some rd8, some dysplasia

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