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Histopathology data for Rigi

Home Genes Rigi Histopathology

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #1 Gall bladder [MA:0000356]
HOM M #2 Thyroid
HOM M #1 Thyroid
HOM M #2 Gall bladder [MA:0000356]
HOM F #3 Brown adipose tissue [MA:0000057]
HOM F #4 Eye [MA:0000261]
HOM M #2 Salivary gland [MA:0000346]
HOM M #1 Nasal cavity [MA:0000284]
HOM M #2 Nasal cavity [MA:0000284]
HOM F #4 Large intestine [MA:0000333]
HOM M #2 Lymph node [MA:0000139] 1 0 Lymph node, mesenteric: Mild, paracortical lymphoid hyperplasia
HOM M #1 Lymph node [MA:0000139]
HOM F #3 Mammary gland [MA:0000145]
HOM F #3 Tibia [MA:0001361]
HOM F #3 Thymus [MA:0000142]
HOM F #3 Spinal cord [MA:0000216]
HOM F #3 Liver [MA:0000358] 1 0 Liver: Mild, focal, neutrophilic and mononuclear cellular infiltrate
HOM F #4 Sciatic nerve [MA:0001172]
HOM M #2 Trachea [MA:0000441]
HOM M #1 Trachea [MA:0000441] 1 0 Trachea: Mild, focal, submucosal glandular cyst
HOM M #2 Bone marrow [MA:0000134]
HOM F #3 Femur [MA:0001359]
HOM F #3 Pancreas [MA:0000120]
HOM M #2 Esophagus [MA:0000352]
HOM M #2 Tooth [MA:0000348]
HOM F #4 Spinal cord [MA:0000216]
HOM M #2 Knee joint [MA:0000471]
HOM M #1 Trigeminal V ganglion [MA:0001080]
HOM M #2 Sciatic nerve [MA:0001172]
HOM M #2 Eye [MA:0000261]
HOM F #4 Gall bladder [MA:0000356]
HOM F #4 Stomach [MA:0000353]
HOM F #4 Tongue [MA:0000347]
HOM F #3 Trigeminal V ganglion [MA:0001080]
HOM M #2 Bone [MA:0001459]
HOM F #4 Lung [MA:0000415]
HOM M #2 Testis [MA:0000411]
HOM M #1 Heart [MA:0000072]
HOM F #3 Adrenal gland [MA:0000116]
HOM F #3 Urinary bladder [MA:0000380]
HOM M #2 Lung [MA:0000415]
HOM M #1 Prostate gland [MA:0000404]
HOM F #3 Bone [MA:0001459]
HOM F #4 Sternum [MA:0001331]
HOM F #3 Salivary gland [MA:0000346]
HOM F #4 Kidney [MA:0000368]
HOM M #2 Ear [MA:0000236]
HOM M #1 Ear [MA:0000236]
HOM F #4 Esophagus [MA:0000352]
HOM F #4 Adrenal gland [MA:0000116]
HOM M #1 Tongue [MA:0000347]
HOM F #3 Spleen [MA:0000141] 1 0 Spleen: Extramedullary hematopoiesis, mild increase
HOM M #2 Stomach [MA:0000353]
HOM F #4 Trachea [MA:0000441]
HOM M #1 Large intestine [MA:0000333]
HOM M #1 Small intestine [MA:0000337]
HOM F #4 Lymph node [MA:0000139] 1 0 Lymph node, mesenteric: Mild, paracortical lymphoid hyperplasia
HOM M #1 Brain [MA:0000168]
HOM F #3 Ovary [MA:0000384]
HOM F #3 Kidney [MA:0000368]
HOM M #1 Esophagus [MA:0000352]
HOM M #1 Bone marrow [MA:0000134]
HOM F #4 Trigeminal V ganglion [MA:0001080]
HOM M #1 Urinary bladder [MA:0000380]
HOM M #2 Large intestine [MA:0000333]
HOM F #4 Heart [MA:0000072]
HOM M #1 Salivary gland [MA:0000346]
HOM M #1 Brown adipose tissue [MA:0000057]
HOM F #4 Thyroid
HOM M #1 Sciatic nerve [MA:0001172]
HOM F #3 Lymph node [MA:0000139] 1 0 Lymph node, mesenteric: Mild, paracortical and follicular lymphoid hyperplasia
HOM M #2 Liver [MA:0000358]
HOM M #1 Testis [MA:0000411]
HOM M #2 Heart [MA:0000072]
HOM M #1 Seminal vesicle [MA:0000410]
HOM M #1 Bone [MA:0001459]
HOM F #3 Small intestine [MA:0000337]
HOM F #4 Nasal cavity [MA:0000284]
HOM F #3 Brain [MA:0000168]
HOM F #4 Mammary gland [MA:0000145]
HOM M #1 Femur [MA:0001359]
HOM F #3 Skin [MA:0000151]
HOM F #4 Bone [MA:0001459]
HOM F #3 Uterus [MA:0000389]
HOM M #2 Femur [MA:0001359]
HOM F #3 Skeletal muscle [MA:0003148]
HOM F #4 Small intestine [MA:0000337]
HOM F #3 Sciatic nerve [MA:0001172]
HOM F #4 Tibia [MA:0001361]
HOM F #4 Ear [MA:0000236]
HOM F #3 Tongue [MA:0000347]
HOM F #3 Eye [MA:0000261]
HOM M #1 Adrenal gland [MA:0000116]
HOM F #3 Bone marrow [MA:0000134]
HOM M #2 Adrenal gland [MA:0000116]
HOM F #3 Esophagus [MA:0000352]
HOM F #3 Heart [MA:0000072]
HOM F #4 Uterus [MA:0000389]
HOM F #4 Skin [MA:0000151]
HOM F #4 Knee joint [MA:0000471]
HOM F #4 Ovary [MA:0000384]
HOM M #2 Sternum [MA:0001331]
HOM M #1 Kidney [MA:0000368]
HOM F #4 Brain [MA:0000168]
HOM M #2 Urinary bladder [MA:0000380]
HOM F #4 Skeletal muscle [MA:0003148]
HOM M #2 Brown adipose tissue [MA:0000057]
HOM M #2 Thymus [MA:0000142]
HOM F #3 Ear [MA:0000236]
HOM M #2 Epididymis [MA:0000397]
HOM M #1 Liver [MA:0000358]
HOM M #1 Tibia [MA:0001361]
HOM M #2 Spinal cord [MA:0000216]
HOM M #1 Spleen [MA:0000141]
HOM M #2 Seminal vesicle [MA:0000410]
HOM F #4 Thymus [MA:0000142]
HOM F #4 Bone marrow [MA:0000134]
HOM F #3 Gall bladder [MA:0000356]
HOM F #3 Thyroid
HOM F #3 Large intestine [MA:0000333]
HOM F #4 Tooth [MA:0000348]
HOM F #3 Knee joint [MA:0000471]
HOM M #1 Lung [MA:0000415]
HOM F #3 Tooth [MA:0000348]
HOM M #2 Prostate gland [MA:0000404]
HOM F #4 Pancreas [MA:0000120]
HOM F #4 Liver [MA:0000358]
HOM F #4 Urinary bladder [MA:0000380]
HOM M #2 Pancreas [MA:0000120]
HOM M #1 Pancreas [MA:0000120]
HOM M #2 Tongue [MA:0000347]
HOM M #2 Skin [MA:0000151]
HOM F #4 Brown adipose tissue [MA:0000057]
HOM M #2 Small intestine [MA:0000337]
HOM M #2 Skeletal muscle [MA:0003148]
HOM M #1 Skeletal muscle [MA:0003148]
HOM M #2 Brain [MA:0000168]
HOM F #4 Spleen [MA:0000141] 1 0 Spleen: Extramedullary hematopoiesis, minimal increase Splenic capsule: Mild, locally extensive, mononuclear capsulitis and mild intracellular hemosiderin
HOM M #1 Stomach [MA:0000353]
HOM F #3 Sternum [MA:0001331]
HOM F #3 Stomach [MA:0000353]
HOM M #2 Kidney [MA:0000368]
HOM F #3 Trachea [MA:0000441]
HOM M #2 Spleen [MA:0000141]
HOM M #1 Sternum [MA:0001331]
HOM F #3 Lung [MA:0000415]
HOM M #1 Tooth [MA:0000348]
HOM F #4 Femur [MA:0001359]
HOM M #2 Trigeminal V ganglion [MA:0001080]
HOM F #3 Nasal cavity [MA:0000284]
HOM M #1 Knee joint [MA:0000471]
HOM M #1 Epididymis [MA:0000397]
HOM M #1 Skin [MA:0000151]
HOM M #1 Eye [MA:0000261] 1 0 Eye, unilateral: Mild, focal retinal dysplasia
HOM M #2 Tibia [MA:0001361]
HOM F #4 Salivary gland [MA:0000346]
HOM M #1 Spinal cord [MA:0000216]
HOM M #1 Thymus [MA:0000142]

Associated histopathology images

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