Severity Score:
- 0 = Normal,
- 1 = Mild (observation barely perceptible and not believed to have clinical significance),
- 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
- 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
- 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)
Significance Score:
- 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
- 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.
Zyg | Sex | Mouse | Tissue | MPATH Process Term | Severity Score | Significance Score | MPATH Diagnostic | PATO Descriptor | Free Text | Images |
---|---|---|---|---|---|---|---|---|---|---|
HOM | M | #3 | Urinary bladder [MA:0000380] | |||||||
HOM | M | #1 | Epididymis [MA:0000397] | |||||||
HOM | M | #3 | Seminal vesicle [MA:0000410] | |||||||
HOM | M | #1 | Prostate gland [MA:0000404] | |||||||
HOM | M | #3 | Epididymis [MA:0000397] | |||||||
HOM | F | #2 | Lymph node [MA:0000139] | 1 | 0 | lymphoid follicular hyperplasia with medullary plasmacytosis | ||||
HOM | F | #4 | Kidney [MA:0000368] | 3 | 1 | unilateral | marked hydronephrosis with cortical atrophy, trigonal and proximal ureteral papillary urothelial hyperplasia, periuretereal lymphocytic infiltration and dysplasia and urothelial intracytoplasmic eosinophilic inclusions | |||
HOM | M | #1 | Liver [MA:0000358] | |||||||
HOM | M | #1 | Urinary bladder [MA:0000380] | |||||||
HOM | F | #2 | Urinary bladder [MA:0000380] | |||||||
HOM | F | #2 | Uterus [MA:0000389] | |||||||
HOM | F | #2 | Liver [MA:0000358] | |||||||
HOM | F | #2 | Ovary [MA:0000384] | |||||||
HOM | M | #3 | Testis [MA:0000411] | |||||||
HOM | M | #1 | Seminal vesicle [MA:0000410] | |||||||
HOM | F | #2 | Kidney [MA:0000368] | 3 | 1 | unilateral | marked hydronephrosis with cortical atrophy, lymphoplasmacytic nephritis, focal trigonal urothelial papillary hyperplasia and urothelial eosinophilic intracytoplasmic inclusions | |||
HOM | M | #3 | Prostate gland [MA:0000404] | |||||||
HOM | F | #4 | Ovary [MA:0000384] | |||||||
HOM | F | #4 | Uterus [MA:0000389] | |||||||
HOM | M | #1 | Testis [MA:0000411] | |||||||
HOM | F | #2 | Salivary gland [MA:0000346] | 1 | 0 | |||||
HOM | M | #1 | Kidney [MA:0000368] | 3 | 1 | unilateral | marked hydronephrosis with cortical atrophy | |||
HOM | F | #4 | Urinary bladder [MA:0000380] | |||||||
HOM | M | #1 | Spleen [MA:0000141] | |||||||
HOM | M | #3 | Kidney [MA:0000368] | 3 | 1 | unilateral | marked hydronephrosis with cortical atrophy, trigonal papillary urothelial hyperplasia and urothelial eosinophilic intracytoplasmic inclusions; proximal ureteral urothelial dysplasia (vs carcinoma) with periureteral lymphocytic infiltration |